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Identification of a novel slow-muscle-fiber enhancer binding protein, MusTRD1.
O'Mahoney JV, Guven KL, Lin J, Joya JE, Robinson CS, Wade RP, Hardeman EC. O'Mahoney JV, et al. Mol Cell Biol. 1998 Nov;18(11):6641-52. doi: 10.1128/MCB.18.11.6641. Mol Cell Biol. 1998. PMID: 9774679 Free PMC article.
The molecular mechanisms which are responsible for restricting skeletal muscle gene expression to specific fiber types, either slow or fast twitch, are unknown. As a first step toward defining the components which direct slow-fiber-specific gene expression, we ident …
The molecular mechanisms which are responsible for restricting skeletal muscle gene expression to specific fiber types, either slow o …
Temperature-dependent growth contributes to long-term cold sensing.
Zhao Y, Antoniou-Kourounioti RL, Calder G, Dean C, Howard M. Zhao Y, et al. Nature. 2020 Jul;583(7818):825-829. doi: 10.1038/s41586-020-2485-4. Epub 2020 Jul 15. Nature. 2020. PMID: 32669706 Free PMC article.
Here, by a forward genetic screen, we identify two dominant mutations of the transcription factor NTL8 that constitutively activate VIN3 expression and alter the slow VIN3 cold induction profile. In the wild type, the NTL8 protein accumulates slowly in the cold, and direct …
Here, by a forward genetic screen, we identify two dominant mutations of the transcription factor NTL8 that constitutively activate VIN3 exp …
Scanning mutagenesis of Mcm1: residues required for DNA binding, DNA bending, and transcriptional activation by a MADS-box protein.
Acton TB, Mead J, Steiner AM, Vershon AK. Acton TB, et al. Mol Cell Biol. 2000 Jan;20(1):1-11. doi: 10.1128/MCB.20.1.1-11.2000. Mol Cell Biol. 2000. PMID: 10594003 Free PMC article.
Our results indicate which residues of Mcm1 are important for viability, transcriptional activation, and DNA binding and bending. Substitution of residues in Mcm1 which are highly conserved among the MADS-box proteins are lethal to the cell and abolish DNA bindin …
Our results indicate which residues of Mcm1 are important for viability, transcriptional activation, and DNA binding and bending. Sub …
Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis.
Timchenko NA, Patel R, Iakova P, Cai ZJ, Quan L, Timchenko LT. Timchenko NA, et al. J Biol Chem. 2004 Mar 26;279(13):13129-39. doi: 10.1074/jbc.M312923200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722059 Free article.
Accumulation of RNA CUG repeats in myotonic dystrophy type 1 (DM1) patients leads to the induction of a CUG-binding protein, CUGBP1, which increases translation of several proteins that are required for myogenesis. ...Immunohistological analysis showed that the skeletal mu …
Accumulation of RNA CUG repeats in myotonic dystrophy type 1 (DM1) patients leads to the induction of a CUG-binding protein, CUGBP1, …
Covalent and ionic nature of the dative bond and account of accurate ammonia borane binding enthalpies.
Plumley JA, Evanseck JD. Plumley JA, et al. J Phys Chem A. 2007 Dec 27;111(51):13472-83. doi: 10.1021/jp074937z. Epub 2007 Dec 5. J Phys Chem A. 2007. PMID: 18052261
HF, B3LYP, MPW1K, MP2, QCISD, and QCISD(T) have been utilized with a wide range of Pople and correlation-consistent basis sets, totaling 336 levels of theory. MPW1K, B3LYP, and HF result in less BSSE and converge to binding enthalpies with fewer basis functions than post-S …
HF, B3LYP, MPW1K, MP2, QCISD, and QCISD(T) have been utilized with a wide range of Pople and correlation-consistent basis sets, totaling 336 …
A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion.
Kenar H, Kose GT, Toner M, Kaplan DL, Hasirci V. Kenar H, et al. Biomaterials. 2011 Aug;32(23):5320-9. doi: 10.1016/j.biomaterials.2011.04.025. Epub 2011 May 12. Biomaterials. 2011. PMID: 21570112 Free PMC article.
The goal of this study was to design and develop a myocardial patch to use in the repair of myocardial infarctions or to slow down tissue damage and improve long-term heart function. The basic 3D construct design involved two biodegradable macroporous tubes, to allow trans …
The goal of this study was to design and develop a myocardial patch to use in the repair of myocardial infarctions or to slow down ti …