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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 4
1982 6
1983 8
1984 7
1985 8
1986 12
1987 10
1988 18
1989 24
1990 38
1991 53
1992 49
1993 71
1994 97
1995 107
1996 120
1997 133
1998 159
1999 187
2000 212
2001 245
2002 322
2003 414
2004 566
2005 690
2006 762
2007 934
2008 1235
2009 1452
2010 1620
2011 1808
2012 2096
2013 2280
2014 2597
2015 2938
2016 3005
2017 3154
2018 3636
2019 4033
2020 4484
2021 5091
2022 5878
2023 6484
2024 3399

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53,776 results

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Page 1
Alginate hydrogel dressings for advanced wound management.
Zhang M, Zhao X. Zhang M, et al. Int J Biol Macromol. 2020 Nov 1;162:1414-1428. doi: 10.1016/j.ijbiomac.2020.07.311. Epub 2020 Aug 7. Int J Biol Macromol. 2020. PMID: 32777428 Review.
Alginate is a natural linear polysaccharide derived from brown algae or bacteria, consisting of repeating units of beta-1,4-linked D-mannuronic acid (M) and L-guluronic acid (G) in different ratios. ...
Alginate is a natural linear polysaccharide derived from brown algae or bacteria, consisting of repeating units of beta-1,4-linked D- …
Interfacial Bioorthogonal Cross-Linking.
Zhang H, Dicker KT, Xu X, Jia X, Fox JM. Zhang H, et al. ACS Macro Lett. 2014 Aug 19;3(8):727-731. doi: 10.1021/mz5002993. Epub 2014 Jul 14. ACS Macro Lett. 2014. PMID: 25177528 Free PMC article.
Described herein is interfacial bioorthogonal cross-linking, the use of bioorthogonal chemistry to create and pattern biomaterials through diffusion-controlled gelation at the liquid-gel interface. ...Syringe delivery of Tz-functionalized hyaluronic acid (HA-Tz) to a bath …
Described herein is interfacial bioorthogonal cross-linking, the use of bioorthogonal chemistry to create and pattern biomaterials th …
Hybrid Cross-Linking to Construct Functional Elastomers.
Zhang L, Chen S, You Z. Zhang L, et al. Acc Chem Res. 2023 Nov 7;56(21):2907-2920. doi: 10.1021/acs.accounts.3c00391. Epub 2023 Oct 11. Acc Chem Res. 2023. PMID: 37819099
Inspired by the simultaneous existence of multiple cross-linked structures in proteins, researchers have employed a hybrid cross-linking strategy to construct elastomers. ...First, we provide a brief introduction of the basic concept of functional elastomers and out …
Inspired by the simultaneous existence of multiple cross-linked structures in proteins, researchers have employed a hybrid cross-l
Applications and Recent Developments of Hydrogels in Ophthalmology.
Wang X, Li F, Liu X, Zhang H. Wang X, et al. ACS Biomater Sci Eng. 2023 Nov 13;9(11):5968-5984. doi: 10.1021/acsbiomaterials.3c00672. Epub 2023 Oct 31. ACS Biomater Sci Eng. 2023. PMID: 37906698 Review.
Hydrogels are a type of functional polymer material with a three-dimensional network structure composed of physically or chemically cross-linked polymers. All hydrogels have two common features: first, their structure contains a large number of hydrophilic groups; therefor …
Hydrogels are a type of functional polymer material with a three-dimensional network structure composed of physically or chemically cross- …
Linking Periodontitis with Inflammatory Bowel Disease through the Oral-Gut Axis: The Potential Role of Porphyromonas gingivalis.
Huang X, Li Y, Zhang J, Feng Q. Huang X, et al. Biomedicines. 2024 Mar 19;12(3):685. doi: 10.3390/biomedicines12030685. Biomedicines. 2024. PMID: 38540299 Free PMC article. Review.
Further, we summarize the possible routes by which P. gingivalis links periodontitis and IBD through the oral-gut axis, as well as the underlying mechanisms of its involvement in the pathogenesis of IBD. ...
Further, we summarize the possible routes by which P. gingivalis links periodontitis and IBD through the oral-gut axis, as well as th …
Genetically proxied intestinal microbiota and risk of erectile dysfunction.
Zhang F, Xiong Y, Zhang Y, Wu K, Zhang B. Zhang F, et al. Andrology. 2024 May;12(4):793-800. doi: 10.1111/andr.13534. Epub 2023 Sep 19. Andrology. 2024. PMID: 37724714
Six methods including inverse variance weighting (IVW), MR-Egger, weighted median, maximum likelihood, MR robust adjusted profile score, and MR pleiotropy residual sum and outlier were used to investigate the causal links between intestinal microbiota and ED. Furthermore, …
Six methods including inverse variance weighting (IVW), MR-Egger, weighted median, maximum likelihood, MR robust adjusted profile score, and …
Improved Cross-Linking Coverage for Protein Complexes Containing Low Levels of Lysine by Using an Enrichable Photo-Cross-Linker.
Zhang B, Gao H, Gong Z, Zhao L, Zhong B, Sui Z, Liang Z, Zhang Y, Zhao Q, Zhang L. Zhang B, et al. Anal Chem. 2023 Jun 27;95(25):9445-9452. doi: 10.1021/acs.analchem.2c05020. Epub 2023 Jun 11. Anal Chem. 2023. PMID: 37303169
Chemical cross-linking coupled with mass spectrometry (XL-MS) is an important technique for the structural analysis of protein complexes where the coverage of amino acids and the identification of cross-linked sites are crucial. Photo-cross-linking has multis …
Chemical cross-linking coupled with mass spectrometry (XL-MS) is an important technique for the structural analysis of protein comple …
Robust Reversible Cross-Linking Strategy for Intracellular Protein Delivery with Excellent Serum Tolerance.
Zhang S, Tan E, Wang R, Gao P, Wang H, Cheng Y. Zhang S, et al. Nano Lett. 2022 Oct 26;22(20):8233-8240. doi: 10.1021/acs.nanolett.2c02948. Epub 2022 Sep 29. Nano Lett. 2022. PMID: 36173109
However, current delivery systems usually have poor serum stability due to the competitive binding of serum proteins to the polymers during delivery. Here, we report a reversible cross-linking strategy to improve the serum stability of polymers for robust intracellular pro …
However, current delivery systems usually have poor serum stability due to the competitive binding of serum proteins to the polymers during …
Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner.
Zhang G, He Y, Liu Y, Du Y, Yang C, Gao F. Zhang G, et al. Cell Death Dis. 2021 Jun 7;12(6):586. doi: 10.1038/s41419-021-03875-6. Cell Death Dis. 2021. PMID: 34099638 Free PMC article.
Our study aimed to clarify the role of HA cross-linking in breast cancer malignancy. Compared to normal mammary gland tissues, cross-linked HA levels were significantly decreased in breast cancer and associated with tumor malignancy. ...Collectively, our study found …
Our study aimed to clarify the role of HA cross-linking in breast cancer malignancy. Compared to normal mammary gland tissues, cross- …
Increased alpha-HB links colorectal cancer and diabetes by potentiating NF-kappaB signaling.
Lv X, Ding P, Li L, Li L, Zhou D, Wang X, Chen J, Zhang W, Wang Q, Liao T, Wen W, Zhou D, Ji QH, He X, Lei QY, Hu W. Lv X, et al. Mol Metab. 2023 Sep;75:101766. doi: 10.1016/j.molmet.2023.101766. Epub 2023 Jul 4. Mol Metab. 2023. PMID: 37406987 Free PMC article.
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. alpha-Hydroxybutyrate (alpha-HB), a byproduct metabolite increased in diabetes and cancer, including colorectal …
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanism …
53,776 results
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