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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1985 1
1987 1
1990 2
1991 1
1992 4
1993 5
1995 1
1996 4
1997 6
1998 8
1999 11
2000 9
2001 19
2002 22
2003 33
2004 49
2005 49
2006 63
2007 85
2008 81
2009 98
2010 108
2011 113
2012 162
2013 175
2014 192
2015 214
2016 247
2017 242
2018 259
2019 326
2020 329
2021 348
2022 409
2023 471
2024 208

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3,855 results

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Page 1
Regulation of SIRT1 and Its Roles in Inflammation.
Yang Y, Liu Y, Wang Y, Chao Y, Zhang J, Jia Y, Tie J, Hu D. Yang Y, et al. Front Immunol. 2022 Mar 11;13:831168. doi: 10.3389/fimmu.2022.831168. eCollection 2022. Front Immunol. 2022. PMID: 35359990 Free PMC article. Review.
SIRT1 affects multiple biological processes by deacetylating a variety of proteins including histones and non-histone proteins. Recent studies have revealed intimate links between SIRT1 and inflammation, while alterations to SIRT1 expression and activity have been linke …
SIRT1 affects multiple biological processes by deacetylating a variety of proteins including histones and non-histone proteins. Recent studi …
Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis.
Jia W, Xie G, Jia W. Jia W, et al. Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):111-128. doi: 10.1038/nrgastro.2017.119. Epub 2017 Oct 11. Nat Rev Gastroenterol Hepatol. 2018. PMID: 29018272 Free PMC article. Review.
An examination of recent research progress in this area is urgently needed. In this Review, we discuss the mechanistic links between bile acids and gastrointestinal carcinogenesis in CRC and HCC, which involve two major bile acid-sensing receptors, farnesoid X receptor (FX …
An examination of recent research progress in this area is urgently needed. In this Review, we discuss the mechanistic links between …
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention.
Liu R, Hong J, Xu X, Feng Q, Zhang D, Gu Y, Shi J, Zhao S, Liu W, Wang X, Xia H, Liu Z, Cui B, Liang P, Xi L, Jin J, Ying X, Wang X, Zhao X, Li W, Jia H, Lan Z, Li F, Wang R, Sun Y, Yang M, Shen Y, Jie Z, Li J, Chen X, Zhong H, Xie H, Zhang Y, Gu W, Deng X, Shen B, Xu X, Yang H, Xu G, Bi Y, Lai S, Wang J, Qi L, Madsen L, Wang J, Ning G, Kristiansen K, Wang W. Liu R, et al. Nat Med. 2017 Jul;23(7):859-868. doi: 10.1038/nm.4358. Epub 2017 Jun 19. Nat Med. 2017. PMID: 28628112
Emerging evidence has linked the gut microbiome to human obesity. We performed a metagenome-wide association study and serum metabolomics profiling in a cohort of lean and obese, young, Chinese individuals. We identified obesity-associated gut microbial species linked …
Emerging evidence has linked the gut microbiome to human obesity. We performed a metagenome-wide association study and serum metabolo …
Interfacial Bioorthogonal Cross-Linking.
Zhang H, Dicker KT, Xu X, Jia X, Fox JM. Zhang H, et al. ACS Macro Lett. 2014 Aug 19;3(8):727-731. doi: 10.1021/mz5002993. Epub 2014 Jul 14. ACS Macro Lett. 2014. PMID: 25177528 Free PMC article.
Described herein is interfacial bioorthogonal cross-linking, the use of bioorthogonal chemistry to create and pattern biomaterials through diffusion-controlled gelation at the liquid-gel interface. ...Syringe delivery of Tz-functionalized hyaluronic acid (HA-Tz) to a bath …
Described herein is interfacial bioorthogonal cross-linking, the use of bioorthogonal chemistry to create and pattern biomaterials th …
Cardiolipin remodeling by ALCAT1 links hypoxia to coronary artery disease by promoting mitochondrial dysfunction.
Jia D, Zhang J, Nie J, Andersen JP, Rendon S, Zheng Y, Liu X, Tian Z, Shi Y. Jia D, et al. Mol Ther. 2021 Dec 1;29(12):3498-3511. doi: 10.1016/j.ymthe.2021.06.007. Epub 2021 Jun 8. Mol Ther. 2021. PMID: 34111561 Free PMC article.
In support of a causative role of ALCAT1 in CHD, we showed that ALCAT1 expression was potently upregulated by MI, linking myocardial hypoxia to oxidative stress, TLCL depletion, and mitochondrial dysfunction. ...
In support of a causative role of ALCAT1 in CHD, we showed that ALCAT1 expression was potently upregulated by MI, linking myocardial …
Uveitis Associated with Juvenile Idiopathic Arthritis.
van Meerwijk C, Kuiper J, van Straalen J, Ayuso VK, Wennink R, Haasnoot AM, Kouwenberg C, de Boer J. van Meerwijk C, et al. Ocul Immunol Inflamm. 2023 Dec;31(10):1906-1914. doi: 10.1080/09273948.2023.2278060. Epub 2023 Dec 14. Ocul Immunol Inflamm. 2023. PMID: 37966463 Review.
The purpose of this mini-review is to summarize the screening strategies and clinical management for JIA-associated uveitis (JIA-U) as well as the current state of molecular markers linked to this condition. Because glaucoma is one of the most common causes o …
The purpose of this mini-review is to summarize the screening strategies and clinical management for JIA-associated uveitis (JIA …
Xylan Plastic.
Jia S, Lv Z, Rao J, Lü B, Chen G, Bian J, Li M, Peng F. Jia S, et al. ACS Nano. 2023 Jul 25;17(14):13627-13637. doi: 10.1021/acsnano.3c02327. Epub 2023 Jul 13. ACS Nano. 2023. PMID: 37439501
Here, xylan plastic (XP) was fabricated by a strategy of double cross-linking through etherification combined with hot pressing. The mechanical properties, particularly the toughness of XP, were significantly enhanced by the incorporation of chemical and physical cross- …
Here, xylan plastic (XP) was fabricated by a strategy of double cross-linking through etherification combined with hot pressing. The …
Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction.
Jia D, Tian Z, Wang R. Jia D, et al. Ageing Res Rev. 2023 Nov;91:102087. doi: 10.1016/j.arr.2023.102087. Epub 2023 Oct 11. Ageing Res Rev. 2023. PMID: 37832607 Review.
This review comprehensive summarizes the benefits of exercise in metabolic diseases, linking mitochondrial dysfunction to the onset of age-related diseases. ...
This review comprehensive summarizes the benefits of exercise in metabolic diseases, linking mitochondrial dysfunction to the onset o …
Genetics of Juvenile Idiopathic Arthritis.
Hersh AO, Prahalad S. Hersh AO, et al. Rheum Dis Clin North Am. 2017 Aug;43(3):435-448. doi: 10.1016/j.rdc.2017.04.007. Rheum Dis Clin North Am. 2017. PMID: 28711144 Review.
Juvenile idiopathic arthritis (JIA) affects approximately 1 in 1000 US children. The cause of JIA is most likely multifactorial and due to an interplay of genetics and environmental factors. ...A brief discussion regarding pharmacogenomics and studies to data lin …
Juvenile idiopathic arthritis (JIA) affects approximately 1 in 1000 US children. The cause of JIA is most likely multifactoria …
PRMT5 links lipid metabolism to contractile function of skeletal muscles.
Kim KH, Jia Z, Snyder M, Chen J, Qiu J, Oprescu SN, Chen X, Syed SA, Yue F, Roseguini BT, Imbalzano AN, Hu C, Kuang S. Kim KH, et al. EMBO Rep. 2023 Aug 3;24(8):e57306. doi: 10.15252/embr.202357306. Epub 2023 Jun 19. EMBO Rep. 2023. PMID: 37334900 Free PMC article.
Skeletal muscle plays a key role in systemic energy homeostasis besides its contractile function, but what links these functions is poorly defined. Protein Arginine Methyl Transferase 5 (PRMT5) is a well-known oncoprotein but also expressed in healthy tissues with unclear …
Skeletal muscle plays a key role in systemic energy homeostasis besides its contractile function, but what links these functions is p …
3,855 results