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2011 1
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2014 1
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2016 5
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2024 3

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38 results

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Page 1
Normal-Weight Central Obesity: Implications for Total and Cardiovascular Mortality.
Sahakyan KR, Somers VK, Rodriguez-Escudero JP, Hodge DO, Carter RE, Sochor O, Coutinho T, Jensen MD, Roger VL, Singh P, Lopez-Jimenez F. Sahakyan KR, et al. Ann Intern Med. 2015 Dec 1;163(11):827-35. doi: 10.7326/M14-2525. Epub 2015 Nov 10. Ann Intern Med. 2015. PMID: 26551006 Free PMC article.
Expected survival estimates were consistently lower for those with central obesity when age and BMI were controlled for. LIMITATIONS: Body fat distribution was assessed based on anthropometric indicators alone. ...
Expected survival estimates were consistently lower for those with central obesity when age and BMI were controlled for. LIMITATIONS: …
Learning Curves of Minimally Invasive Distal Pancreatectomy in Experienced Pancreatic Centers.
Lof S, Claassen L, Hannink G, Al-Sarireh B, Björnsson B, Boggi U, Burdio F, Butturini G, Capretti G, Casadei R, Dokmak S, Edwin B, Esposito A, Fabre JM, Ferrari G, Fretland AA, Ftériche FS, Fusai GK, Giardino A, Groot Koerkamp B, D'Hondt M, Jah A, Kamarajah SK, Kauffmann EF, Keck T, van Laarhoven S, Manzoni A, Marino MV, Marudanayagam R, Molenaar IQ, Pessaux P, Rosso E, Salvia R, Soonawalla Z, Souche R, White S, van Workum F, Zerbi A, Rosman C, Stommel MWJ, Abu Hilal M, Besselink MG; European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS). Lof S, et al. JAMA Surg. 2023 Sep 1;158(9):927-933. doi: 10.1001/jamasurg.2023.2279. JAMA Surg. 2023. PMID: 37378968
Current series on the learning curve of minimally invasive distal pancreatectomy (MIDP) are mostly small, single-center series, thus providing limited data. OBJECTIVE: To evaluate the length of pooled learning curves of MIDP in experienced centers. ...
Current series on the learning curve of minimally invasive distal pancreatectomy (MIDP) are mostly small, single-center series, thus providi …
Characteristics of stroke service implementation in Armenia.
Sahakyan G, Orduyan M, Badalyan S, Adamyan A, Hovhannisyan M, Manucharyan H, Egoyan S, Makaryan Y, Manvelyan H. Sahakyan G, et al. Front Neurol. 2023 Jan 12;13:1021628. doi: 10.3389/fneur.2022.1021628. eCollection 2022. Front Neurol. 2023. PMID: 36712450 Free PMC article.
We believe that our report will serve as a model for achieving advanced and structured stroke care in a resource-limited context and contribute to the future development of the healthcare system in our country....
We believe that our report will serve as a model for achieving advanced and structured stroke care in a resource-limited context and …
Laparoscopic surgery for pancreatic neoplasms: the European association for endoscopic surgery clinical consensus conference.
Edwin B, Sahakyan MA, Abu Hilal M, Besselink MG, Braga M, Fabre JM, Fernández-Cruz L, Gayet B, Kim SC, Khatkov IE; EAES Consensus Conference Study Group. Edwin B, et al. Surg Endosc. 2017 May;31(5):2023-2041. doi: 10.1007/s00464-017-5414-3. Epub 2017 Feb 15. Surg Endosc. 2017. PMID: 28205034
LDP is feasible and safe, performed in many centers, while LPD is limited to few centers. RCTs and registry studies are essential to proceed with the assessment of LAPS....
LDP is feasible and safe, performed in many centers, while LPD is limited to few centers. RCTs and registry studies are essential to …
Search for Origins of Anti-CRISPR Proteins by Structure Comparison.
Sahakyan H, Makarova KS, Koonin EV. Sahakyan H, et al. CRISPR J. 2023 Jun;6(3):222-231. doi: 10.1089/crispr.2023.0011. CRISPR J. 2023. PMID: 37272863 Free PMC article.
Structure comparisons allowed the identification of homologs for 13 of these families that could be ancestors of the Acrs. Despite the limited extent of structural conservation, the inferred origins of Acrs show distinct trends, in particular, recruitment of toxins and ant …
Structure comparisons allowed the identification of homologs for 13 of these families that could be ancestors of the Acrs. Despite the li …
Transcriptome Encyclopedia of Early Human Development.
Sahakyan A, Plath K. Sahakyan A, et al. Cell. 2016 May 5;165(4):777-9. doi: 10.1016/j.cell.2016.04.042. Cell. 2016. PMID: 27153491 Free PMC article.
Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. ...
Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on …
Laparoscopic distal pancreatectomy in patients with poor physical status.
Sahakyan MA, Tholfsen T, Kleive D, Waage A, Buanes T, Labori KJ, Røsok BI, Edwin B. Sahakyan MA, et al. HPB (Oxford). 2021 Jun;23(6):877-881. doi: 10.1016/j.hpb.2020.10.004. Epub 2020 Oct 19. HPB (Oxford). 2021. PMID: 33092964 Free article.
CONCLUSIONS: Poor physical status defined as ASA grades III-IV predicts medical complications, but has a limited impact on surgical complications and severe morbidity of LDP. ...
CONCLUSIONS: Poor physical status defined as ASA grades III-IV predicts medical complications, but has a limited impact on surgical c …
Improving virtual screening results with MM/GBSA and MM/PBSA rescoring.
Sahakyan H. Sahakyan H. J Comput Aided Mol Des. 2021 Jun;35(6):731-736. doi: 10.1007/s10822-021-00389-3. Epub 2021 May 13. J Comput Aided Mol Des. 2021. PMID: 33983518
By allowing to identify computationally putative ligands binding to the proteins of interest, VS dramatically reduces the time and expense of the development of novel therapeutics. Among the limitations of the VS approaches is the low accuracy of scoring functions implemen …
By allowing to identify computationally putative ligands binding to the proteins of interest, VS dramatically reduces the time and expense o …
L-amino acids affect the hydrogenase activity and growth of Ralstonia eutropha H16.
Iskandaryan M, Blbulyan S, Sahakyan M, Vassilian A, Trchounian K, Poladyan A. Iskandaryan M, et al. AMB Express. 2023 Mar 17;13(1):33. doi: 10.1186/s13568-023-01535-w. AMB Express. 2023. PMID: 36932299 Free PMC article.
Hyds are expressed in the presence of gas mixtures (H(2), O(2), CO(2)) or under energy limitation and stress conditions. O(2)-tolerant Hyds are promising candidates as anode biocatalysts in enzymatic fuel cells (EFCs). ...
Hyds are expressed in the presence of gas mixtures (H(2), O(2), CO(2)) or under energy limitation and stress conditions. O(2)-toleran …
Energy-dependent protein folding: modeling how a protein folding machine may work.
Sahakyan H, Nazaryan K, Mushegian A, Sorokina I. Sahakyan H, et al. F1000Res. 2021 Jan 5;10:3. doi: 10.12688/f1000research.28175.1. eCollection 2021. F1000Res. 2021. PMID: 33633838 Free PMC article.
Methods: To show the feasibility of a protein folding machine, we conducted molecular dynamics simulations that were augmented by the application of mechanical force to rotate the C-terminal amino acid while simultaneously limiting the N-terminal amino acid movements. Resu …
Methods: To show the feasibility of a protein folding machine, we conducted molecular dynamics simulations that were augmented by the applic …
38 results