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19 results

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Page 1
Endothelial Dysfunction and Diabetic Cardiomyopathy.
Wang M, Li Y, Li S, Lv J. Wang M, et al. Among authors: li s. Front Endocrinol (Lausanne). 2022 Apr 7;13:851941. doi: 10.3389/fendo.2022.851941. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35464057 Free PMC article. Review.
Hyperglycemia, hyperinsulinemia, and insulin resistance cause the damages of endothelial function, including barrier dysfunction, impaired nitric oxide (NO) activity, excessive reactive oxygen species (ROS) production, oxidative stress, and inflammatory dysregulation. In turn …
Hyperglycemia, hyperinsulinemia, and insulin resistance cause the damages of endothelial function, including barrier dysfunction, impaired n …
Myogenesis controlled by a long non-coding RNA 1700113A16RIK and post-transcriptional regulation.
Fu X, Li S, Jia M, Xu B, Yang L, Ma R, Cheng H, Yang W, Hu P. Fu X, et al. Among authors: li s. Cell Regen. 2022 Apr 3;11(1):13. doi: 10.1186/s13619-022-00114-x. Cell Regen. 2022. PMID: 35366685 Free PMC article.
Mechanistically, 1700113A16RIK may regulate the expression of myogenic genes by directly binding to 3'UTR of an important myogenic transcription factor MEF2D, which in turn promotes the translation of MEF2D. Taken together, our results defined 1700113A16RIK as a positive r …
Mechanistically, 1700113A16RIK may regulate the expression of myogenic genes by directly binding to 3'UTR of an important myogenic transcrip …
Spiritual leadership influence on employee creative service performance: a moderated mediation analysis.
Chiu YW, Amin MW, Li ST, Ali M. Chiu YW, et al. Among authors: li st. BMC Psychol. 2023 Sep 4;11(1):262. doi: 10.1186/s40359-023-01294-0. BMC Psychol. 2023. PMID: 37667394 Free PMC article.
The empirical analysis reveals a positive association between SPL and employee autonomy, which in turn leads to increased employee creative service performance. Furthermore, the results show that SPL indirectly affects employee creative service performance via employee aut …
The empirical analysis reveals a positive association between SPL and employee autonomy, which in turn leads to increased employee cr …
Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy.
Yin J, Yang L, Xie Y, Liu Y, Li S, Yang W, Xu B, Ji H, Ding L, Wang K, Li G, Chen L, Hu P. Yin J, et al. Among authors: li s. Nat Commun. 2018 May 1;9(1):1752. doi: 10.1038/s41467-018-04038-6. Nat Commun. 2018. PMID: 29717119 Free PMC article.
Dkk3 induces nuclear import of beta-catenin and enhances its interaction with FoxO3, which in turn activates the transcription of E3 ubiquitin ligase Fbxo32 and Trim63, driving muscle atrophy. ...
Dkk3 induces nuclear import of beta-catenin and enhances its interaction with FoxO3, which in turn activates the transcription of E3 …
Engulfment and cell motility protein 1 fosters reprogramming of tumor-associated macrophages in colorectal cancer.
Wen B, Li S, Ruan L, Yang Y, Chen Z, Zhang B, Yang X, Jie H, Li S, Zeng Z, Liu S. Wen B, et al. Among authors: li s. Cancer Sci. 2023 Feb;114(2):410-422. doi: 10.1111/cas.15628. Epub 2022 Dec 7. Cancer Sci. 2023. PMID: 36310143 Free PMC article.
Gain- and loss-of-function assays indicated ELMO1 reprogrammed macrophages to a TAM-like phenotype through Rac1 activation. In turn, ELMO1-reprogrammed macrophages were shown to not only facilitate the malignant behaviors of CRC cells but exhibited potent phagocytosis of t …
Gain- and loss-of-function assays indicated ELMO1 reprogrammed macrophages to a TAM-like phenotype through Rac1 activation. In turn, …
Coating peanut shell lignin nanospheres with gelatin via non-covalent adsorption: Key parameters, consequences, and underlying interactions.
Zhou Z, Li S, Zou Y, Lei L, Zhou Y, Wang D, Ye F, Zhao G. Zhou Z, et al. Among authors: li s. Int J Biol Macromol. 2023 Apr 1;233:123607. doi: 10.1016/j.ijbiomac.2023.123607. Epub 2023 Feb 10. Int J Biol Macromol. 2023. PMID: 36773874

The spectral analysis revealed that the interactions between AG and LNS were mainly driven by electrostatic forces (deltaG < 0, deltaH < 0, and deltaS > 0) together with the assistance of hydrogen bonds and hydrophobic interactions, which companied a decrease of alpha-he

…

The spectral analysis revealed that the interactions between AG and LNS were mainly driven by electrostatic forces (deltaG < 0, deltaH &l

…
The AMPK-PP2A axis in insect fat body is activated by 20-hydroxyecdysone to antagonize insulin/IGF signaling and restrict growth rate.
Yuan D, Zhou S, Liu S, Li K, Zhao H, Long S, Liu H, Xie Y, Su Y, Yu F, Li S. Yuan D, et al. Among authors: li s. Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9292-9301. doi: 10.1073/pnas.2000963117. Epub 2020 Apr 10. Proc Natl Acad Sci U S A. 2020. PMID: 32277029 Free PMC article.
During Bombyx larval molt or Drosophila pupariation, high levels of 20E activate AMPK, a molecular sensor that maintains energy homeostasis in the insect fat body. In turn, AMPK activates PP2A, which further dephosphorylates insulin receptor and protein kinase B (AKT), thu …
During Bombyx larval molt or Drosophila pupariation, high levels of 20E activate AMPK, a molecular sensor that maintains energy homeostasis …
Combinational therapeutic targeting of BRD4 and CDK7 synergistically induces anticancer effects in head and neck squamous cell carcinoma.
Zhang W, Ge H, Jiang Y, Huang R, Wu Y, Wang D, Guo S, Li S, Wang Y, Jiang H, Cheng J. Zhang W, et al. Among authors: li s. Cancer Lett. 2020 Jan 28;469:510-523. doi: 10.1016/j.canlet.2019.11.027. Epub 2019 Nov 22. Cancer Lett. 2020. PMID: 31765738
Mechanistically, combinational treatment reduced H3K27ac enrichment in the super-enhancer region of YAP1, which inactivated its transcription and in turn induced anti-proliferative and pro-apoptotic effects. Combined BRD4 and CDK7 upregulation associated with worst prognos …
Mechanistically, combinational treatment reduced H3K27ac enrichment in the super-enhancer region of YAP1, which inactivated its transcriptio …
Performance comparison between rapid sequencing platforms for ultra-low coverage sequencing strategy.
Chen S, Li S, Xie W, Li X, Zhang C, Jiang H, Zheng J, Pan X, Zheng H, Liu JS, Deng Y, Chen F, Jiang H. Chen S, et al. Among authors: li s. PLoS One. 2014 Mar 20;9(3):e92192. doi: 10.1371/journal.pone.0092192. eCollection 2014. PLoS One. 2014. PMID: 24651575 Free PMC article.
These clinical applications, especially prenatal diagnosis, have a strict requirement of turn-around-time; therefore, the application of ULCS is restricted by current high throughput sequencing platforms. ...
These clinical applications, especially prenatal diagnosis, have a strict requirement of turn-around-time; therefore, the application …
Reaction based fluorescent probes for hydrogen sulfide.
Liu C, Peng B, Li S, Park CM, Whorton AR, Xian M. Liu C, et al. Among authors: li s. Org Lett. 2012 Apr 20;14(8):2184-7. doi: 10.1021/ol3008183. Epub 2012 Apr 9. Org Lett. 2012. PMID: 22486842 Free PMC article.
A reaction based fluorescence turn-on strategy for hydrogen sulfide (H(2)S) was developed. This strategy was based on a H(2)S-specific Michael addition-cyclization sequence. Other biological thiols such as cysteine and glutathione did not pursue the reaction and therefore …
A reaction based fluorescence turn-on strategy for hydrogen sulfide (H(2)S) was developed. This strategy was based on a H(2)S-specifi …
19 results