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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1974 1
1983 1
1984 1
1988 1
1989 1
1991 1
1992 2
1993 3
1994 2
1995 3
1996 2
1997 4
1998 1
1999 3
2000 2
2001 7
2002 8
2003 3
2004 3
2005 1
2006 9
2007 6
2008 5
2009 5
2010 5
2011 7
2012 8
2013 13
2014 9
2015 17
2016 21
2017 13
2018 21
2019 24
2020 35
2021 43
2022 55
2023 50
2024 31

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375 results

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Page 1
NAT10 Drives Cisplatin Chemoresistance by Enhancing ac4C-Associated DNA Repair in Bladder Cancer.
Xie R, Cheng L, Huang M, Huang L, Chen Z, Zhang Q, Li H, Lu J, Wang H, Zhou Q, Huang J, Chen X, Lin T. Xie R, et al. Cancer Res. 2023 May 15;83(10):1666-1683. doi: 10.1158/0008-5472.CAN-22-2233. Cancer Res. 2023. PMID: 36939377
Overall, the present study uncovered a mechanism of NAT10-mediated mRNA stabilization in bladder cancer, laying the foundation for NAT10 as a therapeutic target to overcome cisplatin resistance in bladder cancer. ...
Overall, the present study uncovered a mechanism of NAT10-mediated mRNA stabilization in bladder cancer, laying the foundation for NA …
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, Robertson NR, Rayner NW, Loh M, Kim BJ, Chiou J, Miguel-Escalada I, Della Briotta Parolo P, Lin K, Bragg F, Preuss MH, Takeuchi F, Nano J, Guo X, Lamri A, Nakatochi M, Scott RA, Lee JJ, Huerta-Chagoya A, Graff M, Chai JF, Parra EJ, Yao J, Bielak LF, Tabara Y, Hai Y, Steinthorsdottir V, Cook JP, Kals M, Grarup N, Schmidt EM, Pan I, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Long J, Sun M, Tong L, Chen WM, Ahmad M, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Lecoeur C, Prins BP, Nicolas A, Yanek LR, Chen G, Jensen RA, Tajuddin S, Kabagambe EK, An P, Xiang AH, Choi HS, Cade BE, Tan J, Flanagan J, Abaitua F, Adair LS, Adeyemo A, Aguilar-Salinas CA, Akiyama M, Anand SS, Bertoni A, Bian Z, Bork-Jensen J, Brandslund I, Brody JA, Brummett CM, Buchanan TA, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang LM, Cushman M, Das SK, de Silva HJ, Dedoussis G, Dimitrov L, Doumatey AP, Du S, Duan Q, Eckardt KU, Emery LS, Evans DS, Evans MK, Fischer K, Floyd JS, Ford I, Fornage M, F… See abstract for full author list ➔ Mahajan A, et al. Nat Genet. 2022 May;54(5):560-572. doi: 10.1038/s41588-022-01058-3. Epub 2022 May 12. Nat Genet. 2022. PMID: 35551307 Free PMC article.
This improved fine-mapping enabled systematic assessment of candidate causal genes and molecular mechanisms through which T2D associations are mediated, laying the foundations for functional investigations. Multi-ancestry genetic risk scores enhanced transferability of T2D …
This improved fine-mapping enabled systematic assessment of candidate causal genes and molecular mechanisms through which T2D associations a …
Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet.
Yan H, Sun M, Zhang Z, Jin Y, Zhang A, Lin C, Wu B, He M, Xu B, Wang J, Qin P, Mendieta JP, Nie G, Wang J, Jones CS, Feng G, Srivastava RK, Zhang X, Bombarely A, Luo D, Jin L, Peng Y, Wang X, Ji Y, Tian S, Huang L. Yan H, et al. Nat Genet. 2023 Mar;55(3):507-518. doi: 10.1038/s41588-023-01302-4. Epub 2023 Mar 2. Nat Genet. 2023. PMID: 36864101 Free PMC article.
Our study provides a comprehensive genomic resource revealing insights into heat tolerance and laying a foundation for generating more robust crops under the changing climate....
Our study provides a comprehensive genomic resource revealing insights into heat tolerance and laying a foundation for generating mor …
Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma.
Xi Y, Lin Y, Guo W, Wang X, Zhao H, Miao C, Liu W, Liu Y, Liu T, Luo Y, Fan W, Lin A, Chen Y, Sun Y, Ma Y, Niu X, Zhong C, Tan W, Zhou M, Su J, Wu C, Lin D. Xi Y, et al. Signal Transduct Target Ther. 2022 Feb 25;7(1):53. doi: 10.1038/s41392-022-00873-8. Signal Transduct Target Ther. 2022. PMID: 35210398 Free PMC article.
Our DMC-based diagnostic and prognostic panels have potential values for clinical care of ESCC, laying foundations for developing targeted methylation assays for future non-invasive cancer detection methods....
Our DMC-based diagnostic and prognostic panels have potential values for clinical care of ESCC, laying foundations for developing tar …
Tissue-specific regulation of the LIM homeobox gene lin-11 during development of the Caenorhabditis elegans egg-laying system.
Gupta BP, Sternberg PW. Gupta BP, et al. Dev Biol. 2002 Jul 1;247(1):102-15. doi: 10.1006/dbio.2002.0688. Dev Biol. 2002. PMID: 12074555 Free article.
This process is regulated by LET-23-mediated epidermal growth factor signaling and LIN-12-mediated lateral signaling pathways. Among the nuclear factors that act downstream of these pathways, the LIM homeobox gene lin-11 plays a major role. lin-11 mutant anim …
This process is regulated by LET-23-mediated epidermal growth factor signaling and LIN-12-mediated lateral signaling pathways. Among …
Intermetallic Nanocrystals for Fuel-Cells-Based Electrocatalysis.
Lin F, Li M, Zeng L, Luo M, Guo S. Lin F, et al. Chem Rev. 2023 Nov 22;123(22):12507-12593. doi: 10.1021/acs.chemrev.3c00382. Epub 2023 Nov 1. Chem Rev. 2023. PMID: 37910391 Review.
Then, we discuss the state-of-the-art characterizations and representative intermetallic electrocatalysts with emphasis on oxygen reduction reaction evaluated in a MEA setup. We summarize this review by laying out existing challenges and offering perspective on future rese …
Then, we discuss the state-of-the-art characterizations and representative intermetallic electrocatalysts with emphasis on oxygen reduction …
The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans.
Bettinger JC, Euling S, Rougvie AE. Bettinger JC, et al. Development. 1997 Nov;124(21):4333-42. doi: 10.1242/dev.124.21.4333. Development. 1997. PMID: 9334281
First, LIN-29 accumulates in many non-hypodermal cells with known roles in vulva formation or egg laying. ...Finally, vulval morphogenesis and egg laying requires lin-29 activity within the EMS lineage, a lineage that does not generate hypodermal cells …
First, LIN-29 accumulates in many non-hypodermal cells with known roles in vulva formation or egg laying. ...Finally, vulval m …
Radiation-induced liver injury and hepatocyte senescence.
Zhu W, Zhang X, Yu M, Lin B, Yu C. Zhu W, et al. Cell Death Discov. 2021 Sep 16;7(1):244. doi: 10.1038/s41420-021-00634-6. Cell Death Discov. 2021. PMID: 34531376 Free PMC article. Review.
This review aims to systematically profile the overall mechanism of RILI and the effects of radiation on hepatocyte senescence, laying foundations for the development of new therapies....
This review aims to systematically profile the overall mechanism of RILI and the effects of radiation on hepatocyte senescence, laying …
Insulin-like growth factor-1 is involved in the deteriorated performance of aged laying hens.
Xin Q, Uyanga VA, Jiao H, Zhao J, Wang X, Li H, Zhou Y, Lin H. Xin Q, et al. J Anim Sci. 2022 Nov 1;100(11):skac286. doi: 10.1093/jas/skac286. J Anim Sci. 2022. PMID: 36049215 Free PMC article.
The underlying mechanism behind the deteriorated laying performance of aged laying hens remains unclear. In the present study, the laying performance and gene expression along the hypothalamus-pituitary-gonad axis were determined. A total of 300 healthy 90-wk …
The underlying mechanism behind the deteriorated laying performance of aged laying hens remains unclear. In the present study, …
375 results