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Sex-differences in circulating biomarkers during acute myocardial infarction: An analysis from the SWEDEHEART registry.
Eggers KM, Lindhagen L, Baron T, Erlinge D, Hjort M, Jernberg T, Johnston N, Marko-Varga G, Rezeli M, Spaak J, Lindahl B. Eggers KM, et al. PLoS One. 2021 Apr 8;16(4):e0249830. doi: 10.1371/journal.pone.0249830. eCollection 2021. PLoS One. 2021. PMID: 33831096 Free PMC article.
Two multimarker panels were applied (Proximity Extension Assay [Olink Bioscience], Multiple Reaction Monitoring mass spectrometry). Lasso analysis (penalized logistic regression), multiple testing-corrected Mann-Whitney tests and Cox regressions were used to assess sex-dif …
Two multimarker panels were applied (Proximity Extension Assay [Olink Bioscience], Multiple Reaction Monitoring mass spectrometry). Lasso …
Predicting outcome in acute myocardial infarction: an analysis investigating 175 circulating biomarkers.
Eggers KM, Lindhagen L, Lindhagen L, Baron T, Erlinge D, Hjort M, Jernberg T, Marko-Varga G, Rezeli M, Spaak J, Lindahl B. Eggers KM, et al. Eur Heart J Acute Cardiovasc Care. 2021 Oct 1;10(7):806-812. doi: 10.1093/ehjacc/zuaa014. Eur Heart J Acute Cardiovasc Care. 2021. PMID: 34100060
The prognostic value of biomarkers regarding all-cause mortality, recurrent MI, and heart failure hospitalizations (median follow-up 6.6 years) was studied using Lasso analysis, a penalized logistic regression model that considers all biomarkers simultaneously while minimi …
The prognostic value of biomarkers regarding all-cause mortality, recurrent MI, and heart failure hospitalizations (median follow-up 6.6 yea …
Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study.
Lindahl LM, Besenbacher S, Rittig AH, Celis P, Willerslev-Olsen A, Gjerdrum LMR, Krejsgaard T, Johansen C, Litman T, Woetmann A, Odum N, Iversen L. Lindahl LM, et al. Blood. 2018 Feb 15;131(7):759-770. doi: 10.1182/blood-2017-06-788950. Epub 2017 Dec 5. Blood. 2018. PMID: 29208599 Free article.
The patients were subdivided into a discovery cohort (n = 82) and an independent validation cohort (n = 72). The miRNA classifier was built using a LASSO (least absolute shrinkage and selection operator) Cox regression to predict progression-free survival (PFS). ...
The patients were subdivided into a discovery cohort (n = 82) and an independent validation cohort (n = 72). The miRNA classifier was built …
Increased Inflammatory Activity in Patients 3 Months after Myocardial Infarction with Nonobstructive Coronary Arteries.
Hjort M, Eggers KM, Lindhagen L, Agewall S, Brolin EB, Collste O, Daniel M, Ekenbäck C, Frick M, Henareh L, Hofman-Bang C, Malmqvist K, Spaak J, Sörensson P, Y-Hassan S, Tornvall P, Lindahl B. Hjort M, et al. Clin Chem. 2019 Aug;65(8):1023-1030. doi: 10.1373/clinchem.2018.301085. Epub 2019 May 9. Clin Chem. 2019. PMID: 31072836
METHODS: Ninety-one biomarkers were measured with a proximity extension assay 3 months after MI in 97 MINOCA patients, 97 age- and sex-matched MI-CAD patients, and 98 controls. Lasso analyses (penalized logistic regression models) and adjusted multiple linear regression mo …
METHODS: Ninety-one biomarkers were measured with a proximity extension assay 3 months after MI in 97 MINOCA patients, 97 age- and sex-match …
Differences in biomarker concentrations and predictions of long-term outcome in patients with ST-elevation and non-ST-elevation myocardial infarction.
Hjort M, Eggers KM, Lindhagen L, Baron T, Erlinge D, Jernberg T, Marko-Varga G, Rezeli M, Spaak J, Lindahl B. Hjort M, et al. Clin Biochem. 2021 Dec;98:17-23. doi: 10.1016/j.clinbiochem.2021.09.001. Epub 2021 Sep 5. Clin Biochem. 2021. PMID: 34496288 Free article. Clinical Trial.
Blood samples were collected day 1-3 after admission and 175 biomarkers were analyzed using Proximity Extension Assay and Multiple Reaction Monitoring mass spectrometry. Adjusted Lasso analysis (penalized logistic regression model) was used to select biomarkers that discri …
Blood samples were collected day 1-3 after admission and 175 biomarkers were analyzed using Proximity Extension Assay and Multiple Reaction …