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CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.
Sci Transl Med. 2020 Aug 26;12(558):eaaz8664. doi: 10.1126/scitranslmed.aaz8664.
Sci Transl Med. 2020.
PMID: 32848096
Free PMC article.
Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.
Palmer CJ, Bruckner RJ, Paulo JA, Kazak L, Long JZ, Mina AI, Deng Z, LeClair KB, Hall JA, Hong S, Zushin PH, Smith KL, Gygi SP, Hagen S, Cohen DE, Banks AS.
Palmer CJ, et al. Among authors: smith kl.
Mol Metab. 2017 Oct;6(10):1212-1225. doi: 10.1016/j.molmet.2017.07.013. Epub 2017 Jul 31.
Mol Metab. 2017.
PMID: 29031721
Free PMC article.
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