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Identification of Estrogen Receptor Modulators as Inhibitors of Flavivirus Infection.
Eyre NS, Kirby EN, Anfiteatro DR, Bracho G, Russo AG, White PA, Aloia AL, Beard MR. Eyre NS, et al. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e00289-20. doi: 10.1128/AAC.00289-20. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32482672 Free PMC article.
Subsequent validation studies revealed that these drugs effectively inhibit ZIKV, DENV, and WNV (Kunjin strain) infection at low micromolar concentrations with minimal cytotoxicity in Huh-7.5 hepatoma cells and HTR-8 placental trophoblast cells. ...
Subsequent validation studies revealed that these drugs effectively inhibit ZIKV, DENV, and WNV (Kunjin strain) infection at low micr …
Seroprevalence of Japanese encephalitis virus-specific antibodies in Australia following novel epidemic spread: protocol for a national cross-sectional study.
Winkler NE, Koirala A, Kaur G, Prasad S, Hirani R, Baker J, Hoad V, Gosbell IB, Irving DO, Hueston L, O'Sullivan MV, Kok J, Dwyer DE, Macartney K; Australian Japanese Encephalitis Virus Serosurvey Group; Australian Japanese encephalitis virus serosurvey group. Winkler NE, et al. BMJ Open. 2024 Feb 7;14(2):e075569. doi: 10.1136/bmjopen-2023-075569. BMJ Open. 2024. PMID: 38326269 Free PMC article.
Samples are tested for JEV-specific total antibody using a defined epitope-blocking ELISA, and total antibody to Australian endemic flaviviruses Murray Valley encephalitis and Kunjin viruses. ANALYSIS: Two analytic approaches will occur: descriptive estimates of seropreval …
Samples are tested for JEV-specific total antibody using a defined epitope-blocking ELISA, and total antibody to Australian endemic flavivir …
Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene.
Park JS, Yang JM, Min MK. Park JS, et al. Biochem Biophys Res Commun. 2000 Jan 19;267(2):581-7. doi: 10.1006/bbrc.1999.1999. Biochem Biophys Res Commun. 2000. PMID: 10631105
In this study, on the basis of the fact that the core and NS4B proteins of Kunjin virus translocate into the nucleus, we were prompted to investigate whether the HCV nonstructural protein NS4B has any function in tumor formation. ...
In this study, on the basis of the fact that the core and NS4B proteins of Kunjin virus translocate into the nucleus, we were prompte …