Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription.
Iannucci LF, D'Erchia AM, Picardi E, Bettio D, Conca F, Surdo NC, Di Benedetto G, Musso D, Arrigoni C, Lolicato M, Vismara M, Grisan F, Salviati L, Milanesi L, Pesole G, Lefkimmiatis K.
Iannucci LF, et al.
Nat Commun. 2023 Sep 8;14(1):5521. doi: 10.1038/s41467-023-41088-x.
Nat Commun. 2023.
PMID: 37684224
Free PMC article.
Collectively, our data reveal an unexpected mechanism through which cyclic AMP contributes to nuclear spatial compartmentalization and promotes the transcription of specific genes....
Collectively, our data reveal an unexpected mechanism through which cyclic AMP contributes to nuclear spatial compartmentalization and promo …