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Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.
Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.
Direct observation and catalytic role of mediator atom in 2D materials.
Lee GD, Robertson AW, Lee S, Lin YC, Oh JW, Park H, Joo YC, Yoon E, Suenaga K, Warner JH, Ewels CP. Lee GD, et al. Sci Adv. 2020 Jun 10;6(24):eaba4942. doi: 10.1126/sciadv.aba4942. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32577521 Free PMC article.
For a long time, a core concept in understanding the structural evolution of graphene defects has been the Stone-Thrower-Wales (STW)-type bond rotation. In this study, we show that undercoordinated atoms induce bond formation and breaking, with much lower energy barriers t …
For a long time, a core concept in understanding the structural evolution of graphene defects has been the Stone-Thrower-Wales (STW)- …
Femtosecond laser lithotripsy: feasibility and ablation mechanism.
Qiu J, Teichman JM, Wang T, Neev J, Glickman RD, Chan KF, Milner TE. Qiu J, et al. J Biomed Opt. 2010 Mar-Apr;15(2):028001. doi: 10.1117/1.3368998. J Biomed Opt. 2010. PMID: 20459291 Free article.
Largest crater volumes were achieved on CYST stones, among the most difficult stones to fragment using Holmium:YAG (Ho:YAG) lithotripsy. Diameter of debris was characterized using optical microscopy and found to be less than 20 microm, substantially smaller than tha …
Largest crater volumes were achieved on CYST stones, among the most difficult stones to fragment using Holmium:YAG (Ho:YAG) li …
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia.
Keeton EK, McEachern K, Dillman KS, Palakurthi S, Cao Y, Grondine MR, Kaur S, Wang S, Chen Y, Wu A, Shen M, Gibbons FD, Lamb ML, Zheng X, Stone RM, Deangelo DJ, Platanias LC, Dakin LA, Chen H, Lyne PD, Huszar D. Keeton EK, et al. Blood. 2014 Feb 6;123(6):905-13. doi: 10.1182/blood-2013-04-495366. Epub 2013 Dec 20. Blood. 2014. PMID: 24363397 Free PMC article.