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Year Number of Results
1981 2
1982 3
1983 25
1984 71
1985 148
1986 294
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1988 644
1989 1014
1990 1346
1991 1925
1992 2224
1993 2478
1994 2587
1995 2872
1996 2959
1997 2895
1998 3045
1999 2953
2000 2861
2001 2571
2002 2369
2003 2377
2004 2444
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2006 2267
2007 2192
2008 2109
2009 2144
2010 2158
2011 2144
2012 2156
2013 2091
2014 1928
2015 1800
2016 1507
2017 1392
2018 1442
2019 1336
2020 1286
2021 1150
2022 974
2023 839
2024 263

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69,006 results

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(11)C-DPA-713 Versus (18)F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke.
Chaney A, Cropper HC, Johnson EM, Lechtenberg KJ, Peterson TC, Stevens MY, Buckwalter MS, James ML. Chaney A, et al. J Nucl Med. 2019 Jan;60(1):122-128. doi: 10.2967/jnumed.118.209155. Epub 2018 Jul 5. J Nucl Med. 2019. PMID: 29976695 Free PMC article.
Accordingly, the aim of this study was to directly compare 2 promising second-generation TSPO tracers, (11)C-DPA-713 and (18)F-GE-180, for the first time at acute and chronic time points after ischemic stroke. ...Conclusion:(11)C-DPA-713 and (18)F-GE-180 PET enable …
Accordingly, the aim of this study was to directly compare 2 promising second-generation TSPO tracers, (11)C-DPA-713 and (18)F-GE-180 …
Efficient and automatic synthesis of TSPO PET ligand [(18)F]-GE-180 and its application in rheumatoid arthritis model.
Zhu XX, He YL, Xie JK, Wang KX, Wang SC, Xie Q. Zhu XX, et al. Appl Radiat Isot. 2022 Jun;184:110213. doi: 10.1016/j.apradiso.2022.110213. Epub 2022 Mar 23. Appl Radiat Isot. 2022. PMID: 35349890
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic synovial inflammation, which ultimately leads to joint deformity and dysfunction. [(18)F]-GE-180 is a specific PET tracer of the 18 kDa translocator protein (TSPO), which is overexpres …
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic synovial inflammation, which ultimately leads to joint def …
Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms.
Olson JK, Bishop GA, Grose C. Olson JK, et al. J Virol. 1997 Jan;71(1):110-9. doi: 10.1128/JVI.71.1.110-119.1997. J Virol. 1997. PMID: 8985329 Free PMC article.
The recombinant baculovirus gE product had a molecular mass of 64 kDa, smaller than the previously documented 98 kDa of mature gE expressed in mammalian cells. ...When recombinant gE produced in HeLa cells was probed with the same antiphosphotyr …
The recombinant baculovirus gE product had a molecular mass of 64 kDa, smaller than the previously documented 98 kDa of …
Letter to the Editor re: Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [(18)F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter.
Zanotti-Fregonara P, Veronese M, Rizzo G, Pascual B, Masdeu JC, Turkheimer FE. Zanotti-Fregonara P, et al. Mol Imaging Biol. 2020 Feb;22(1):10-12. doi: 10.1007/s11307-019-01433-3. Mol Imaging Biol. 2020. PMID: 31641965 No abstract available.
Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [(18)F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter.
Sridharan S, Raffel J, Nandoskar A, Record C, Brooks DJ, Owen D, Sharp D, Muraro PA, Gunn R, Nicholas R. Sridharan S, et al. Mol Imaging Biol. 2019 Oct;21(5):935-944. doi: 10.1007/s11307-019-01323-8. Mol Imaging Biol. 2019. PMID: 30796709 Free article. Clinical Trial.
PROCEDURES: Twelve people with MS underwent baseline MRI and 90-min dynamic [(18)F]GE-180 PET or [(11)C]PBR28 PET (n = 6; three HAB, three MAB each). ...RESULTS: Whole brain V(T) (mean standard deviation) was 0.29 0.17 ml/cm(3) for [(18)F]GE-180 and 5.01 1.88 ml/cm( …
PROCEDURES: Twelve people with MS underwent baseline MRI and 90-min dynamic [(18)F]GE-180 PET or [(11)C]PBR28 PET (n = 6; three HAB, …
Accumulation of 22 kDa alpha-zein-mediated nonzein protein in protein body of maize endosperm.
Feng Y, Ma Y, Feng F, Chen X, Qi W, Ma Z, Song R. Feng Y, et al. New Phytol. 2022 Jan;233(1):265-281. doi: 10.1111/nph.17796. Epub 2021 Nov 2. New Phytol. 2022. PMID: 34637530 Free article.
To investigate its accumulation mechanism to PBs, we performed protein interaction assays between major zein proteins and NZP1, and found that NZP1 interacts with 22 kDa alpha-zein. Levels of NZP1 and 22 kDa alpha-zein in various opaque mutants were correlated. Furt …
To investigate its accumulation mechanism to PBs, we performed protein interaction assays between major zein proteins and NZP1, and found th …
Fully automated radiosynthesis of [11C]PBR28, a radiopharmaceutical for the translocator protein (TSPO) 18 kDa, using a GE TRACERlab FXC-Pro.
Hoareau R, Shao X, Henderson BD, Scott PJ. Hoareau R, et al. Appl Radiat Isot. 2012 Aug;70(8):1779-83. doi: 10.1016/j.apradiso.2012.03.006. Epub 2012 Mar 29. Appl Radiat Isot. 2012. PMID: 22503515
In this communication we highlight our novel, recently developed, one-pot synthesis of the desmethyl-PBR28 precursor, as well as present an optimized fully automated preparation of [(11)C]PBR28 using a GE TRACERlab FX(C-Pro). Following radiolabelling, purification is achie …
In this communication we highlight our novel, recently developed, one-pot synthesis of the desmethyl-PBR28 precursor, as well as present an …
Miniaturization of Bright Light-Emitting Luciferase ALuc: picALuc.
Ohmuro-Matsuyama Y, Furuta T, Matsui H, Kanai M, Ueda H. Ohmuro-Matsuyama Y, et al. ACS Chem Biol. 2022 Apr 15;17(4):864-872. doi: 10.1021/acschembio.1c00897. Epub 2022 Mar 16. ACS Chem Biol. 2022. PMID: 35293729
Recently, small bright luciferases such as artificial luciferase (ALuc) (21 kDa), NanoLuc (19 kDa), GLuc (18 kDa), and TurboLuc (16 kDa) have been reported. ...Here, we constructed the smallest and bright mutant of ALuc, named "picALuc" (13 kDa) …
Recently, small bright luciferases such as artificial luciferase (ALuc) (21 kDa), NanoLuc (19 kDa), GLuc (18 kDa), and …
A glycine-rich bovine herpesvirus 5 (BHV-5) gE-specific epitope within the ectodomain is important for BHV-5 neurovirulence.
Al-Mubarak A, Zhou Y, Chowdhury SI. Al-Mubarak A, et al. J Virol. 2004 May;78(9):4806-16. doi: 10.1128/jvi.78.9.4806-4816.2004. J Virol. 2004. PMID: 15078962 Free PMC article.
Pulse-chase analyses revealed that the epitope-deleted and wild-type gE were synthesized as N-glycosylated endoglycosidase H-sensitive precursors with approximate molecular masses of 85 kDa and 86 kDa, respectively. ...Concomitantly, the epitope-deleted and w …
Pulse-chase analyses revealed that the epitope-deleted and wild-type gE were synthesized as N-glycosylated endoglycosidase H-sensitiv …
Longitudinal [(18)F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model.
Holzgreve A, Pötter D, Brendel M, Orth M, Weidner L, Gold L, Kirchner MA, Bartos LM, Unterrainer LM, Unterrainer M, Steiger K, von Baumgarten L, Niyazi M, Belka C, Bartenstein P, Riemenschneider MJ, Lauber K, Albert NL. Holzgreve A, et al. Biomedicines. 2022 Mar 22;10(4):738. doi: 10.3390/biomedicines10040738. Biomedicines. 2022. PMID: 35453488 Free PMC article.
The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). ...In GBM mice, [18F]GE-180 uptake continuously increased over time, e.g., at day 11, mean TBRmax +16% compared to day 4, p = 0.011. [18 …
The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). ... …
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