A viral ADP-ribosyltransferase attaches RNA chains to host proteins.
Wolfram-Schauerte M, Pozhydaieva N, Grawenhoff J, Welp LM, Silbern I, Wulf A, Billau FA, Glatter T, Urlaub H, Jäschke A, Höfer K.
Wolfram-Schauerte M, et al.
Nature. 2023 Aug;620(7976):1054-1062. doi: 10.1038/s41586-023-06429-2. Epub 2023 Aug 16.
Nature. 2023.
PMID: 37587340
Free PMC article.
T4 phages that express an inactive mutant of ModB have a decreased burst size and slowed lysis of E. coli. Our findings reveal a distinct biological role for NAD-RNA, namely the activation of the RNA for enzymatic transfer to proteins. ...
T4 phages that express an inactive mutant of ModB have a decreased burst size and slowed lysis of E. coli. Our findings reveal a dist …