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Page 1
Effects of Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: A Systematic Review and Meta-Analysis.
Pan KL, Singer DE, Ovbiagele B, Wu YL, Ahmed MA, Lee M. Pan KL, et al. Among authors: lee m. J Am Heart Assoc. 2017 Jul 18;6(7):e005835. doi: 10.1161/JAHA.117.005835. J Am Heart Assoc. 2017. PMID: 28720644 Free PMC article. Review.
BACKGROUND: The original non-vitamin K antagonist oral anticoagulant (NOAC) trials in nonvalvular atrial fibrillation (AF) enrolled patients with native valve pathologies. ...
BACKGROUND: The original non-vitamin K antagonist oral anticoagulant (NOAC) trials in nonvalvular atrial fibrillation (AF) enrolled p …
Comparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry.
Chen CH, Lee CW, Hsieh YC, Lin CJ, Chen YW, Lin KH, Sung PS, Tang CW, Chu HJ, Tsai KC, Chou CL, Lin CH, Wei CY, Yen SY, Chen PL, Yeh HL, Chan L, Sung SF, Lee M, Liu HM, Lin YH, Lee IH, Yeh SJ, Lien LM, Chiou HY, Lee JT, Tang SC, Jeng JS; Taiwan Registry of Endovascular Thrombectomy for Acute Ischemic Stroke (TREAT-AIS) Investigators. Chen CH, et al. Among authors: lee m. Stroke. 2024 Mar;55(3):532-540. doi: 10.1161/STROKEAHA.123.045851. Epub 2024 Feb 5. Stroke. 2024. PMID: 38314590 Free PMC article.
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase : a novel approach in the prevention of osteoclastogenesis.
Zhang Y, Jiang B, Zhang P, Chiu SK, Lee MH. Zhang Y, et al. Among authors: lee mh. Bone Joint Res. 2022 Nov;11(11):763-776. doi: 10.1302/2046-3758.1111.BJR-2022-0147.R2. Bone Joint Res. 2022. PMID: 36331083 Free PMC article.
At the messenger RNA level, T1(PralphaTACE) strongly attenuated expression of key osteoclast marker genes that included TRAP, cathepsin K, osteoclast stimulatory transmembrane protein (OC-STAMP), dendritic cell-specific transmembrane protein (DC-STAMP), osteoclast-associat …
At the messenger RNA level, T1(PralphaTACE) strongly attenuated expression of key osteoclast marker genes that included TRAP, cathepsin K …
Association of Intracranial Hemorrhage Risk With Non-Vitamin K Antagonist Oral Anticoagulant Use vs Aspirin Use: A Systematic Review and Meta-analysis.
Huang WY, Singer DE, Wu YL, Chiang CE, Weng HH, Lee M, Ovbiagele B. Huang WY, et al. Among authors: lee m. JAMA Neurol. 2018 Dec 1;75(12):1511-1518. doi: 10.1001/jamaneurol.2018.2215. JAMA Neurol. 2018. PMID: 30105396 Free PMC article.
IMPORTANCE: Non-vitamin K antagonist oral anticoagulants (NOACs) might be an attractive choice for stroke prevention in people without atrial fibrillation who may harbor a potential source of cardiac emboli, but not if certain individual NOACs carry risks of intracranial h …
IMPORTANCE: Non-vitamin K antagonist oral anticoagulants (NOACs) might be an attractive choice for stroke prevention in people withou …
Targeting a Designer TIMP-1 to the Cell Surface for Effective MT1-MMP Inhibition: A Potential Role for the Prion Protein in Renal Carcinoma Therapy.
Jiang B, Liu J, Lee MH. Jiang B, et al. Among authors: lee mh. Molecules. 2019 Jan 11;24(2):255. doi: 10.3390/molecules24020255. Molecules. 2019. PMID: 30641935 Free PMC article.
In this study, we describe a novel strategy that would enable a "designer" TIMP-1 tailored specifically for MT1-MMP inhibition (V4A/P6V/T98L; K(i)(app) 1.66 nM) to be targeted to the plasma membrane for more effective MT1-MMP inhibition. ...
In this study, we describe a novel strategy that would enable a "designer" TIMP-1 tailored specifically for MT1-MMP inhibition (V4A/P6V/T98L …
ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
Guo C, Tsigkou A, Lee MH. Guo C, et al. Among authors: lee mh. Biomed Rep. 2016 Jan;4(1):73-78. doi: 10.3892/br.2015.535. Epub 2015 Oct 30. Biomed Rep. 2016. PMID: 26870338 Free PMC article.
While ADAMTS13 is also not sensitive to the hydroxamate inhibitors, batimastat and ilomastat, ADAMTS15 can be effectively inhibited by batimastat (K(i)(app) 299 nM). In conclusion, the present results indicate that TIMPs are not the regulators of these two ADAMTS proteinas …
While ADAMTS13 is also not sensitive to the hydroxamate inhibitors, batimastat and ilomastat, ADAMTS15 can be effectively inhibited by batim …