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Ferrostatin-1 modulates dysregulated kidney lipids in acute kidney injury.
Martín-Saiz L, Guerrero-Mauvecin J, Martín-Sanchez D, Fresnedo O, Gómez MJ, Carrasco S, Cannata-Ortiz P, Ortiz A, Fernandez JA, Sanz AB. Martín-Saiz L, et al. Among authors: fernandez ja. J Pathol. 2022 Jul;257(3):285-299. doi: 10.1002/path.5882. Epub 2022 Mar 23. J Pathol. 2022. PMID: 35152438
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) was used to assess kidney lipidomics and it discriminated between glomeruli, medulla, and cortex in control kidneys, AKI kidneys, and AKI + Ferrostatin-1 kidneys. ...
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) was used to assess kidney lipidomics and it discriminate …
Distribution of lipids in human brain.
Veloso A, Fernández R, Astigarraga E, Barreda-Gómez G, Manuel I, Giralt MT, Ferrer I, Ochoa B, Rodríguez-Puertas R, Fernández JA. Veloso A, et al. Among authors: fernandez ja. Anal Bioanal Chem. 2011 Jul;401(1):89-101. doi: 10.1007/s00216-011-4882-x. Epub 2011 Mar 26. Anal Bioanal Chem. 2011. PMID: 21437774
The present study shows the lipid distribution obtained by MALDI-TOF IMS in human frontal cortex, hippocampus, and striatal area, together with functional autoradiography of cannabinoid and LPA receptors. ...
The present study shows the lipid distribution obtained by MALDI-TOF IMS in human frontal cortex, hippocampus, and striatal area, tog …
3K3A-Activated Protein C Protects the Blood-Brain Barrier and Neurons From Accelerated Ischemic Injury Caused by Pericyte Deficiency in Mice.
Wang Y, Kisler K, Nikolakopoulou AM, Fernandez JA, Griffin JH, Zlokovic BV. Wang Y, et al. Among authors: fernandez ja. Front Neurosci. 2022 Mar 30;16:841916. doi: 10.3389/fnins.2022.841916. eCollection 2022. Front Neurosci. 2022. PMID: 35431776 Free PMC article.
These changes were accompanied by 50% increase in both immunoglobulin G and fibrinogen pericapillary deposits in the ischemic cortex 8 h after tMCAo indicating an accelerated BBB breakdown, and 35 and 55% greater losses of pericyte coverage and number of degenerating neuro …
These changes were accompanied by 50% increase in both immunoglobulin G and fibrinogen pericapillary deposits in the ischemic cortex …
Anatomical distribution of lipids in human brain cortex by imaging mass spectrometry.
Veloso A, Astigarraga E, Barreda-Gómez G, Manuel I, Ferrer I, Giralt MT, Ochoa B, Fresnedo O, Rodríguez-Puertas R, Fernández JA. Veloso A, et al. Among authors: fernandez ja. J Am Soc Mass Spectrom. 2011 Feb;22(2):329-38. doi: 10.1007/s13361-010-0024-5. Epub 2011 Jan 28. J Am Soc Mass Spectrom. 2011. PMID: 21472592
To address this issue, we have performed-by means of MALDI-TOF mass spectrometry-imaging on slices and lipidomic analysis in extracts of frontal cortex, both from the same postmortem tissue samples of human brain. ...
To address this issue, we have performed-by means of MALDI-TOF mass spectrometry-imaging on slices and lipidomic analysis in extracts of fro …