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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1959 1
1964 1
1977 1
1980 1
1982 1
1983 1
1984 2
1986 1
1987 3
1988 20
1989 27
1990 23
1991 24
1992 33
1993 32
1994 31
1995 47
1996 57
1997 60
1998 60
1999 75
2000 76
2001 102
2002 123
2003 123
2004 94
2005 160
2006 175
2007 166
2008 189
2009 154
2010 175
2011 195
2012 195
2013 229
2014 283
2015 352
2016 367
2017 404
2018 399
2019 432
2020 518
2021 621
2022 633
2023 545
2024 188

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6,579 results

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Page 1
Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis.
Förstermann U, Xia N, Li H. Förstermann U, et al. Circ Res. 2017 Feb 17;120(4):713-735. doi: 10.1161/CIRCRESAHA.116.309326. Circ Res. 2017. PMID: 28209797 Review.
Animal studies have provided compelling evidence demonstrating the roles of vascular oxidative stress and NO in atherosclerosis. All established cardiovascular risk factors such as hypercholesterolemia, hypertension, diabetes mellitus, and smoking enhance ROS generation an …
Animal studies have provided compelling evidence demonstrating the roles of vascular oxidative stress and NO in atherosclerosis. All …
Caspase-8: The double-edged sword.
Mandal R, Barrón JC, Kostova I, Becker S, Strebhardt K. Mandal R, et al. Biochim Biophys Acta Rev Cancer. 2020 Apr;1873(2):188357. doi: 10.1016/j.bbcan.2020.188357. Epub 2020 Mar 5. Biochim Biophys Acta Rev Cancer. 2020. PMID: 32147543 Review.
Caspase-8 is a cysteine - aspartate specific protease that classically triggers the extrinsic apoptotic pathway, in response to the activation of cell surface Death Receptors (DRs) like FAS, TRAIL-R and TNF-R. Besides it's roles in triggering death receptor-mediated apopto …
Caspase-8 is a cysteine - aspartate specific protease that classically triggers the extrinsic apoptotic pathway, in response to the activati …
History of Diabetes Insipidus.
Valenti G, Tamma G. Valenti G, et al. G Ital Nefrol. 2016 Feb;33 Suppl 66:33.S66.1. G Ital Nefrol. 2016. PMID: 26913870 Free article.
In 1670s Thomas Willis, noted the difference in taste of urine from polyuric subjects compared with healthy individuals and started the differentiation of Diabetes Mellitus from the more rare entity of Diabetes Insipidus. In 1794, Johann Peter Frank described polyuric pati …
In 1670s Thomas Willis, noted the difference in taste of urine from polyuric subjects compared with healthy individuals and started the diff …
Adrenoceptors-New roles for old players.
Michel MC, Bond RA, Summers RJ. Michel MC, et al. Br J Pharmacol. 2019 Jul;176(14):2339-2342. doi: 10.1111/bph.14701. Br J Pharmacol. 2019. PMID: 31240712 Free PMC article.
This article is part of a themed section on Adrenoceptors-New Roles for Old Players. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.14/issuetoc....
This article is part of a themed section on Adrenoceptors-New Roles for Old Players. To view the other articles in this section visit …
SARS-CoV-PLpro-Inhibitoren als mögliche Breitspektrum-Virostatika.
Hammerschmidt SJ, Müller P, Schirmeister T. Hammerschmidt SJ, et al. Biospektrum (Heidelb). 2021;27(3):254-256. doi: 10.1007/s12268-021-1576-6. Epub 2021 May 11. Biospektrum (Heidelb). 2021. PMID: 33994673 Free PMC article. Review. German.
The SARS-CoV-encoded papain-like cysteine protease (PL(pro)) plays crucial roles in viral replication and maturation processes. It is required to cleave the precursor polyproteins into functional proteins. ...
The SARS-CoV-encoded papain-like cysteine protease (PL(pro)) plays crucial roles in viral replication and maturation processes. It is …
Physiological and unappreciated roles of CaMKII in the heart.
Beckendorf J, van den Hoogenhof MMG, Backs J. Beckendorf J, et al. Basic Res Cardiol. 2018 Jun 15;113(4):29. doi: 10.1007/s00395-018-0688-8. Basic Res Cardiol. 2018. PMID: 29905892 Free PMC article. Review.
In this review, we provide a brief overview of the physiological and pathophysiological properties of CaMKII signaling, but we focus on the physiological and adaptive functions of CaMKII. Furthermore, special consideration is given to the emerging role of CaMKII as a media …
In this review, we provide a brief overview of the physiological and pathophysiological properties of CaMKII signaling, but we focus on the …
Macrophages and platelets in liver fibrosis and hepatocellular carcinoma.
Casari M, Siegl D, Deppermann C, Schuppan D. Casari M, et al. Front Immunol. 2023 Dec 5;14:1277808. doi: 10.3389/fimmu.2023.1277808. eCollection 2023. Front Immunol. 2023. PMID: 38116017 Free PMC article. Review.
In liver cancer, they are attracted to the tumor site to become tumor-associated macrophages (TAMs) polarized towards a M2- anti-inflammatory/tumor-promoting phenotype. Besides their role in thrombosis and hemostasis, platelets can also stimulate fibrosis and tumor develop …
In liver cancer, they are attracted to the tumor site to become tumor-associated macrophages (TAMs) polarized towards a M2- anti-inflammator …
Roles of factor Xa beyond coagulation.
Ruf W. Ruf W. J Thromb Thrombolysis. 2021 Aug;52(2):391-396. doi: 10.1007/s11239-021-02458-8. Epub 2021 Apr 24. J Thromb Thrombolysis. 2021. PMID: 33893900 Free PMC article.
Because thrombotic and thrombo-inflammatory diseases are frequently caused by excessive activation of the tissue factor (TF) pathway, activation of FX by the TF-FVIIa complex is of central importance for understanding the roles of FXa in thrombosis and hemostasis and funct …
Because thrombotic and thrombo-inflammatory diseases are frequently caused by excessive activation of the tissue factor (TF) pathway, activa …
Thromboinflammation and Vascular Dysfunction.
Karbach S, Lagrange J, Wenzel P. Karbach S, et al. Hamostaseologie. 2019 Jun;39(2):180-187. doi: 10.1055/s-0038-1676130. Epub 2018 Dec 4. Hamostaseologie. 2019. PMID: 30513535 Review.
Thromboinflammation and vascular dysfunction are inseparably combined with the innate and the adaptive immune response. While the role of this interplay has gained considerable attention in the arena of atherosclerosis/atherothrombosis and in deep vein thrombosis, its r …
Thromboinflammation and vascular dysfunction are inseparably combined with the innate and the adaptive immune response. While the role …
To move or not to move: roles and specificity of plant RNA mobility.
Maizel A, Markmann K, Timmermans M, Wachter A. Maizel A, et al. Curr Opin Plant Biol. 2020 Oct;57:52-60. doi: 10.1016/j.pbi.2020.05.005. Epub 2020 Jul 4. Curr Opin Plant Biol. 2020. PMID: 32634685 Free article. Review.
Particular emphasis is given to novel insight into the specificity determinants of messenger RNA mobility, the role of small RNA movement in development, and the specificity of RNA exchange in plant-plant and plant-microbe interactions....
Particular emphasis is given to novel insight into the specificity determinants of messenger RNA mobility, the role of small RNA move …
6,579 results