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A programmable encapsulation system improves delivery of therapeutic bacteria in mice.
Harimoto T, Hahn J, Chen YY, Im J, Zhang J, Hou N, Li F, Coker C, Gray K, Harr N, Chowdhury S, Pu K, Nimura C, Arpaia N, Leong KW, Danino T. Harimoto T, et al. Among authors: zhang j. Nat Biotechnol. 2022 Aug;40(8):1259-1269. doi: 10.1038/s41587-022-01244-y. Epub 2022 Mar 17. Nat Biotechnol. 2022. PMID: 35301496 Free PMC article.
Single-sequence protein structure prediction using a language model and deep learning.
Chowdhury R, Bouatta N, Biswas S, Floristean C, Kharkar A, Roy K, Rochereau C, Ahdritz G, Zhang J, Church GM, Sorger PK, AlQuraishi M. Chowdhury R, et al. Among authors: zhang j. Nat Biotechnol. 2022 Nov;40(11):1617-1623. doi: 10.1038/s41587-022-01432-w. Epub 2022 Oct 3. Nat Biotechnol. 2022. PMID: 36192636 Free PMC article.
Engineered bacterial therapeutics for detecting and treating CRC.
Siguenza N, Brevi A, Zhang JT, Pabani A, Bhushan A, Das M, Ding Y, Hasty J, Ghosh P, Zarrinpar A. Siguenza N, et al. Among authors: zhang jt. Trends Cancer. 2024 Apr 30:S2405-8033(24)00074-8. doi: 10.1016/j.trecan.2024.04.001. Online ahead of print. Trends Cancer. 2024. PMID: 38693003 Review.
Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.
Lee M, Li J, Li J, Fang S, Zhang J, Vo ATT, Han W, Zeng H, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Sun D, Huang Y. Lee M, et al. Among authors: zhang j. Cancer Res. 2021 Apr 15;81(8):1965-1976. doi: 10.1158/0008-5472.CAN-20-3213. Epub 2021 Feb 15. Cancer Res. 2021. PMID: 33589517 Free PMC article.
An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila.
Kockel L, Griffin C, Ahmed Y, Fidelak L, Rajan A, Gould EP, Haigney M, Ralston B, Tercek RJ, Galligani L, Rao S, Huq L, Bhargava HK, Dooner AC, Lemmerman EG, Malusa RF, Nguyen TH, Chung JS, Gregory SM, Kuwana KM, Regenold JT, Wei A, Ashton J, Dickinson P, Martel K, Cai C, Chen C, Price S, Qiao J, Shepley D, Zhang J, Chalasani M, Nguyen K, Aalto A, Kim B, Tazawa-Goodchild E, Sherwood A, Rahman A, Wu SYC, Lotzkar J, Michaels S, Aristotle H, Clark A, Gasper G, Xiang E, Schlör FL, Lu M, Haering K, Friberg J, Kuwana A, Lee J, Liu A, Norton E, Hamad L, Lee C, Okeremi D, diTullio H, Dumoulin K, Chi SYG, Derossi GS, Horowitch RE, Issa EC, Le DT, Morales BC, Noori A, Shao J, Cho S, Hoang MN, Johnson IM, Lee KC, Lee M, Madamidola EA, Schmitt KE, Byan G, Park T, Chen J, Monovoukas A, Kang MJ, McGowan T, Walewski JJ, Simon B, Zu SJ, Miller GP, Fitzpatrick KB, Lantz N, Fox E, Collette J, Kurtz R, Duncan C, Palmer R, Rotondo C, Janicki E, Chisholm T, Rankin A, Park S, Kim SK. Kockel L, et al. Among authors: zhang j. G3 (Bethesda). 2019 Jul 9;9(7):2097-2106. doi: 10.1534/g3.119.400105. G3 (Bethesda). 2019. PMID: 31040111 Free PMC article.
Rapid screening of engineered microbial therapies in a 3D multicellular model.
Harimoto T, Singer ZS, Velazquez OS, Zhang J, Castro S, Hinchliffe TE, Mather W, Danino T. Harimoto T, et al. Among authors: zhang j. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9002-9007. doi: 10.1073/pnas.1820824116. Epub 2019 Apr 17. Proc Natl Acad Sci U S A. 2019. PMID: 30996123 Free PMC article.