Purpose: The aim of this study was to analyze the clinical features, treatment and factors affecting the prognosis of patients with central salivary gland tumors of the jaws.
Methods: Twenty-two patients with central salivary gland tumors of the jaws at West China Hospital of Stomatology, Sichuan University in the recent 20 years were retrospectively analyzed according to the clinical features, treatment and factors affecting the prognosis. A thorough review of clinical records was performed and the histological diagnosis was revised according to the 2005 WHO criteria.
Results: Most central salivary gland tumors of the jaws occurred in middle-aged females. Diagnosis was difficult because clinical manifestations were not typical as swelling of the jaws, pain and tooth mobility were common. Most of these diseases were malignant and pathological types were diverse. Mucoepidermoid carcinoma was the most common type. Surgery was the primary treatment plan.
Conclusions: It can be concluded that the final diagnosis in most patients with central salivary gland tumors of the jaws is acquired by preoperative biopsy. Surgery was the primary treatment method and radical resection is the first choice for the patients. The resection of sufficient frontier could reduce the chance of recurrence to a great extent.