Targeting DNA G-quadruplexes with helical small molecules.
Müller S, Laxmi-Reddy K, Jena PV, Baptiste B, Dong Z, Godde F, Ha T, Rodriguez R, Balasubramanian S, Huc I.
Müller S, et al. Among authors: jena pv.
Chembiochem. 2014 Nov 24;15(17):2563-70. doi: 10.1002/cbic.201402439. Epub 2014 Sep 26.
Chembiochem. 2014.
PMID: 25256604
Free PMC article.
Given the vast array of morphologies G-quadruplex structures can adopt, this might be a way to achieve sequence selective binding. Here, we describe the design and synthesis of molecules based on macrocyclic and helically folded oligoamides. ...
Given the vast array of morphologies G-quadruplex structures can adopt, this might be a way to achieve sequence selective binding. He …