Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2018 1
2019 2
2020 1
2022 1
2023 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

6 results

Results by year

Filters applied: . Clear all
Page 1
Lumasiran for Advanced Primary Hyperoxaluria Type 1: Phase 3 ILLUMINATE-C Trial.
Michael M, Groothoff JW, Shasha-Lavsky H, Lieske JC, Frishberg Y, Simkova E, Sellier-Leclerc AL, Devresse A, Guebre-Egziabher F, Bakkaloglu SA, Mourani C, Saqan R, Singer R, Willey R, Habtemariam B, Gansner JM, Bhan I, McGregor T, Magen D. Michael M, et al. Am J Kidney Dis. 2023 Feb;81(2):145-155.e1. doi: 10.1053/j.ajkd.2022.05.012. Epub 2022 Jul 14. Am J Kidney Dis. 2023. PMID: 35843439 Free article. Clinical Trial.
ILLUMINATE-C evaluates the efficacy, safety, pharmacokinetics, and pharmacodynamics of lumasiran in patients with PH1 and advanced kidney disease. STUDY DESIGN: Phase 3, open-label, single-arm trial. SETTING & PARTICIPANTS: Multinational study; enrolled patients with P …
ILLUMINATE-C evaluates the efficacy, safety, pharmacokinetics, and pharmacodynamics of lumasiran in patients with PH1 and advanced kidney di …
Drugs in Focus: Domperidone.
Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Puoti MG, et al. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. J Pediatr Gastroenterol Nutr. 2023. PMID: 37159421 Review.
However, among (pediatric) gastroenterologists, domperidone is also used outside its authorized indication ("off label") for treatment of symptoms associated with gastro-esophageal reflux disease, dyspepsia, and gastroparesis. Little is known about its efficacy in the trea …
However, among (pediatric) gastroenterologists, domperidone is also used outside its authorized indication ("off label") for treatmen …
Chemical Modification of 1-Aminocyclopropane Carboxylic Acid (ACC) Oxidase: Cysteine Mutational Analysis, Characterization, and Bioconjugation with a Nitroxide Spin Label.
Tachon S, Fournier E, Decroos C, Mansuelle P, Etienne E, Maresca M, Martinho M, Belle V, Tron T, Simaan AJ. Tachon S, et al. Mol Biotechnol. 2019 Sep;61(9):650-662. doi: 10.1007/s12033-019-00191-5. Mol Biotechnol. 2019. PMID: 31201604
By a combination of approaches including directed mutagenesis, activity screening on cell extracts, biophysical and biochemical characterization of purified enzymes, we evaluated the effect of native cysteine replacement and that of insertion of cysteines on the C-terminal part i …
By a combination of approaches including directed mutagenesis, activity screening on cell extracts, biophysical and biochemical characteriza …
Using Machine Learning to Identify True Somatic Variants from Next-Generation Sequencing.
Wu C, Zhao X, Welsh M, Costello K, Cao K, Abou Tayoun A, Li M, Sarmady M. Wu C, et al. Clin Chem. 2020 Jan 1;66(1):239-246. doi: 10.1373/clinchem.2019.308213. Clin Chem. 2020. PMID: 31672855
METHODS: A cohort of 11278 SNVs identified through clinical sequencing of tumor specimens was collected and divided into training, validation, and test sets. Each SNV was manually inspected and labeled as either real or artifact as part of clinical laboratory workflow. ... …
METHODS: A cohort of 11278 SNVs identified through clinical sequencing of tumor specimens was collected and divided into training, validatio …
STEP-CD study: ustekinumab use in paediatric Crohn's disease-a multicentre retrospective study from paediatric IBD Porto group of ESPGHAN.
Pujol-Muncunill G, Navas-López VM, Ledder O, Cohen S, Lekar M, Turner D, Kolho KL, Levine A, Croft NM, Bronsky J, Shouval DS, Assa A, Harris R, Kiparissi F, Aloi M, Afzal NA, Tzivinikos C, Barrio J, Norden C, Vega MJB, Buderus S, de Valderrama AF, de Ridder L, García-Romero R, Medina E, Sánchez C, Velasco M, Vicente S, Wilson DC, Naik S, Hradsky O, Cococcioni L, Martin-de-Carpi J. Pujol-Muncunill G, et al. Eur J Pediatr. 2024 May 3. doi: 10.1007/s00431-024-05588-2. Online ahead of print. Eur J Pediatr. 2024. PMID: 38700692
What is Known: Ustekinumab is an effective therapy for adult moderate to severe Crohn's disease (CD). Off-label use of ustekinumab in children is increasing especially in anti-TNF refractory CD. ...
What is Known: Ustekinumab is an effective therapy for adult moderate to severe Crohn's disease (CD). Off-label use of ustekinumab in …
Risk of post-operative hemorrhage after adenoidectomy and tonsillectomy: Value of the preoperative determination of partial thromboplastin time and prothrombin time.
Bitar M, Dunya G, Khalifee E, Muwakkit S, Barazi R. Bitar M, et al. Int J Pediatr Otorhinolaryngol. 2019 Jan;116:62-64. doi: 10.1016/j.ijporl.2018.10.024. Epub 2018 Oct 19. Int J Pediatr Otorhinolaryngol. 2019. PMID: 30554709
All patients had preoperative CBC, PT, and aPTT ordered. According to the results, patients were labelled as either "abnormal group" or "normal group". RESULTS: 35 patients had abnormal lab results 18 of these patients were diagnosed with coagulation disorders on further l …
All patients had preoperative CBC, PT, and aPTT ordered. According to the results, patients were labelled as either "abnormal group" …