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2015 | 1 |
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Br J Surg. 2021 Sep 27;108(9):1056-1063. doi: 10.1093/bjs/znab101.
Br J Surg. 2021.
PMID: 33761533
Free PMC article.
Yap Regulates Muller Glia Reprogramming in Damaged Zebrafish Retinas.
Lourenço R, Brandão AS, Borbinha J, Gorgulho R, Jacinto A.
Lourenço R, et al.
Front Cell Dev Biol. 2021 Sep 20;9:667796. doi: 10.3389/fcell.2021.667796. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 34616723
Free PMC article.
Here, we show that Yap is required in Muller glia to engage their response to a lesion by regulating their cell cycle reentry and progenitor cell formation, contributing to the differentiation of new photoreceptors. We propose that this regulation is accomplished through a …
Here, we show that Yap is required in Muller glia to engage their response to a lesion by regulating their cell cycle reentry and pro …
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Yap induces osteoblast differentiation by modulating Bmp signalling during zebrafish caudal fin regeneration.
Brandão AS, Bensimon-Brito A, Lourenço R, Borbinha J, Soares AR, Mateus R, Jacinto A.
Brandão AS, et al.
J Cell Sci. 2019 Nov 14;132(22):jcs231993. doi: 10.1242/jcs.231993.
J Cell Sci. 2019.
PMID: 31636113
Here, we use zebrafish caudal fin regeneration as a model to clarify how the Hippo pathway regulates de novo bone formation and osteoblast differentiation. We demonstrate that Yap inhibition leads to accumulation of osteoprogenitors and prevents osteoblast differentiation …
Here, we use zebrafish caudal fin regeneration as a model to clarify how the Hippo pathway regulates de novo bone formation and osteoblast d …
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Control of tissue growth by Yap relies on cell density and F-actin in zebrafish fin regeneration.
Mateus R, Lourenço R, Fang Y, Brito G, Farinho A, Valério F, Jacinto A.
Mateus R, et al.
Development. 2015 Aug 15;142(16):2752-63. doi: 10.1242/dev.119701. Epub 2015 Jul 24.
Development. 2015.
PMID: 26209644
Free PMC article.
However, how this is established and regulated is not well understood. Here, we report that Yap, the Hippo pathway effector, is a chief player in this process: functionally manipulating Yap during regeneration dramatically affects cell proliferation and expression o …
However, how this is established and regulated is not well understood. Here, we report that Yap, the Hippo pathway effector, is a chi …
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Weaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In Vitro.
Cohen AS, Yap DB, Lewis ME, Chijiwa C, Ramos-Arroyo MA, Tkachenko N, Milano V, Fradin M, McKinnon ML, Townsend KN, Xu J, Van Allen MI, Ross CJ, Dobyns WB, Weaver DD, Gibson WT.
Cohen AS, et al.
Hum Mutat. 2016 Mar;37(3):301-7. doi: 10.1002/humu.22946. Epub 2016 Jan 12.
Hum Mutat. 2016.
PMID: 26694085
Free PMC article.
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