Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches.
Cozzi SJ, Ogbourne SM, James C, Rebel HG, de Gruijl FR, Ferguson B, Gardner J, Lee TT, Larcher T, Suhrbier A.
Cozzi SJ, et al.
J Invest Dermatol. 2012 Apr;132(4):1263-71. doi: 10.1038/jid.2011.418. Epub 2011 Dec 22.
J Invest Dermatol. 2012.
PMID: 22189786
Free article.
Application of 0.05% ingenol mebutate gel to photo-damaged skin resulted in a 70% reduction in the number of skin lesions that subsequently emerged compared with placebo treatment. Ingenol mebutate treatment also reduced the number of mutant p53 keratinocyte patches …
Application of 0.05% ingenol mebutate gel to photo-damaged skin resulted in a 70% reduction in the number of skin lesions that subseq …