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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 1
1948 3
1949 1
1950 4
1951 3
1952 1
1953 1
1954 4
1955 3
1956 3
1957 7
1958 6
1959 10
1960 3
1961 4
1962 11
1963 11
1964 12
1965 11
1966 10
1967 15
1968 15
1969 15
1970 17
1971 14
1972 13
1973 16
1974 64
1975 72
1976 84
1977 104
1978 88
1979 174
1980 182
1981 189
1982 209
1983 285
1984 352
1985 336
1986 394
1987 556
1988 634
1989 628
1990 708
1991 577
1992 651
1993 771
1994 920
1995 932
1996 999
1997 1163
1998 1127
1999 1249
2000 1484
2001 1597
2002 1831
2003 2173
2004 2585
2005 2988
2006 3298
2007 3747
2008 4120
2009 4654
2010 5432
2011 6126
2012 6864
2013 7787
2014 8837
2015 9722
2016 10031
2017 10501
2018 11683
2019 13689
2020 16259
2021 17263
2022 18099
2023 17722
2024 6915

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185,666 results

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Page 1
Use of Hu-PBL Mice to Study Pathogenesis of Human-Restricted Viruses.
Brunetti JE, Kitsera M, Muñoz-Fontela C, Rodríguez E. Brunetti JE, et al. Viruses. 2023 Jan 13;15(1):228. doi: 10.3390/v15010228. Viruses. 2023. PMID: 36680271 Free PMC article. Review.
Different humanized mouse models have been developed to study human diseases such as autoimmune illnesses, cancer and viral infections. These models are based on the use of immunodeficient mouse strains that are transplanted with human tissues or human immune …
Different humanized mouse models have been developed to study human diseases such as autoimmune illnesses, cancer and viral infection …
The development and improvement of immunodeficient mice and humanized immune system mouse models.
Chen J, Liao S, Xiao Z, Pan Q, Wang X, Shen K, Wang S, Yang L, Guo F, Liu HF, Pan Q. Chen J, et al. Front Immunol. 2022 Oct 19;13:1007579. doi: 10.3389/fimmu.2022.1007579. eCollection 2022. Front Immunol. 2022. PMID: 36341323 Free PMC article. Review.
Animal models play an indispensable role in the study of human diseases. However, animal models of different diseases do not fully mimic the complex internal environment of humans. ...We describe existing humanized immune system mouse models based on immunodeficient …
Animal models play an indispensable role in the study of human diseases. However, animal models of different diseases do not fully mi …
SCID-hu-PBL: a model for making human antibodies?
Ifversen P, Borrebaeck CA. Ifversen P, et al. Semin Immunol. 1996 Aug;8(4):243-8. doi: 10.1006/smim.1996.0030. Semin Immunol. 1996. PMID: 8883147 Review.
The ability of SCID mice to accept xenografts has been utilized in the search for a laboratory model that mimics the human immune system. Intraperitoneal injection of human peripheral blood lymphocytes into SCID mice constitutes a feasible and easy way of establishi …
The ability of SCID mice to accept xenografts has been utilized in the search for a laboratory model that mimics the human immune sys …
Humanizing Intensive Care: From Theory to Practice.
Velasco Bueno JM, La Calle GH. Velasco Bueno JM, et al. Crit Care Nurs Clin North Am. 2020 Jun;32(2):135-147. doi: 10.1016/j.cnc.2020.02.001. Crit Care Nurs Clin North Am. 2020. PMID: 32402312 Review.
The International Research Project for the Humanization of Intensive Care Units (Proyecto HU-CI) was initiated in 2014. The aim of this project is to change the current paradigm toward a human-centered care model. ...
The International Research Project for the Humanization of Intensive Care Units (Proyecto HU-CI) was initiated in 2014. The aim of th …
Human T-and B-cell functions in SCID-hu mice.
Roncarolo MG, Carballido JM, Rouleau M, Namikawa R, de Vries JE. Roncarolo MG, et al. Semin Immunol. 1996 Aug;8(4):207-13. doi: 10.1006/smim.1996.0026. Semin Immunol. 1996. PMID: 8883143 Review.
SCID mice transplanted with human fetal liver and thymus (SCID-hu Thy/Liv) provide a unique in-vivo model to study human T-cell development and clonal selection mechanisms. ...In addition, these mice have circulating human T cells, which mediate hum …
SCID mice transplanted with human fetal liver and thymus (SCID-hu Thy/Liv) provide a unique in-vivo model to study human …
Human-robot facial coexpression.
Hu Y, Chen B, Lin J, Wang Y, Wang Y, Mehlman C, Lipson H. Hu Y, et al. Sci Robot. 2024 Mar 27;9(88):eadi4724. doi: 10.1126/scirobotics.adi4724. Epub 2024 Mar 27. Sci Robot. 2024. PMID: 38536902
Here, we propose that both barriers can be alleviated by training a robot to anticipate future facial expressions and execute them simultaneously with a human. Whereas delayed facial mimicry looks disingenuous, facial coexpression feels more genuine because it requires cor …
Here, we propose that both barriers can be alleviated by training a robot to anticipate future facial expressions and execute them simultane …
The human immune system in hu-PBL-SCID mice.
Tary-Lehmann M, Saxon A, Lehmann PV. Tary-Lehmann M, et al. Immunol Today. 1995 Nov;16(11):529-33. doi: 10.1016/0167-5699(95)80046-8. Immunol Today. 1995. PMID: 7495490 Review.
Severe combined immunodeficiency (SCID) mice can be stably grafted with human peripheral blood lymphocytes, creating hu-PBL-SCID chimeras; essentially, these are mice with a human immune system. Here, Magdalena Tary-Lehmann, Andrew Saxon and Paul Lehmann disc …
Severe combined immunodeficiency (SCID) mice can be stably grafted with human peripheral blood lymphocytes, creating hu-PBL-SC …
Preclinical evaluation of human hematolymphoid function in the SCID-hu mouse.
McCune JM, Péault B, Streeter PR, Rabin L. McCune JM, et al. Immunol Rev. 1991 Dec;124:45-62. doi: 10.1111/j.1600-065x.1991.tb00615.x. Immunol Rev. 1991. PMID: 1804780 Review.
Work in the SCID-hu system has progressed significantly over the past 3-4 years. Reliable SCID-hu constructs can now be created for the evaluation of long-term multilineage human hematopoiesis, human immune function, and HIV infection of human h …
Work in the SCID-hu system has progressed significantly over the past 3-4 years. Reliable SCID-hu constructs can now be create …
EBV-induced human B cell lymphomas in hu-PBL-SCID mice.
Mosier DE, Picchio GR, Kirven MB, Garnier JL, Torbett BE, Baird SM, Kobayashi R, Kipps TJ. Mosier DE, et al. AIDS Res Hum Retroviruses. 1992 May;8(5):735-40. AIDS Res Hum Retroviruses. 1992. PMID: 1325170 Review.
Epstein-Barr virus (EBV) infection is associated with Burkitt's lymphoma (BL) in normal individuals and immunoblastic B cell lymphomas in immunosuppressed or HIV-infected individuals. SCID mice reconstituted with human peripheral blood leukocytes (hu-PBL-SCID) from …
Epstein-Barr virus (EBV) infection is associated with Burkitt's lymphoma (BL) in normal individuals and immunoblastic B cell lymphomas in im …
Is there still evolution in the human population?
Kun Á. Kun Á. Biol Futur. 2022 Dec;73(4):359-374. doi: 10.1007/s42977-022-00146-z. Epub 2023 Jan 2. Biol Futur. 2022. PMID: 36592324 Free PMC article. Review.
185,666 results
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