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Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers.
Nana AW, Wu SY, Yang YS, Chin YT, Cheng TM, Ho Y, Li WS, Liao YM, Chen YR, Shih YJ, Liu YR, Pedersen J, Incerpi S, Hercbergs A, Liu LF, Whang-Peng J, Davis PJ, Lin HY. Nana AW, et al. Among authors: ho y. Horm Cancer. 2018 Oct;9(5):349-360. doi: 10.1007/s12672-018-0334-9. Epub 2018 Jul 20. Horm Cancer. 2018. PMID: 30027502 Free PMC article.
Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R.
Ho Y, Sh Yang YC, Chin YT, Chou SY, Chen YR, Shih YJ, Whang-Peng J, Changou CA, Liu HL, Lin SJ, Tang HY, Lin HY, Davis PJ. Ho Y, et al. Food Chem Toxicol. 2018 Oct;120:346-355. doi: 10.1016/j.fct.2018.07.030. Epub 2018 Jul 17. Food Chem Toxicol. 2018. PMID: 30026090
Our findings suggest that resveratrol can be considered an alternative therapeutic agent for myomas....
Our findings suggest that resveratrol can be considered an alternative therapeutic agent for myomas....
Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status.
Chin YT, He ZR, Chen CL, Chu HC, Ho Y, Su PY, Yang YSH, Wang K, Shih YJ, Chen YR, Pedersen JZ, Incerpi S, Nana AW, Tang HY, Lin HY, Mousa SA, Davis PJ, Whang-Peng J. Chin YT, et al. Among authors: ho y. Front Endocrinol (Lausanne). 2019 Mar 12;10:130. doi: 10.3389/fendo.2019.00130. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 30915033 Free PMC article.
Colorectal cancer is a serious medical problem in Taiwan. New, effective therapeutic approaches are needed. The selection of promising anticancer drugs and the transition from pre-clinical investigations to clinical trials are often challenging. ...
Colorectal cancer is a serious medical problem in Taiwan. New, effective therapeutic approaches are needed. The selection of promisin …
Combining structure-based pharmacophore and in silico approaches to discover novel selective serotonin reuptake inhibitors.
Zhou ZL, Liu HL, Wu JW, Tsao CW, Chen WH, Liu KT, Ho Y. Zhou ZL, et al. Among authors: ho y. Chem Biol Drug Des. 2013 Dec;82(6):705-17. doi: 10.1111/cbdd.12192. Epub 2013 Aug 10. Chem Biol Drug Des. 2013. PMID: 23865625
To our knowledge, the present work is the first structure-based virtual screening study for new SSRI discovery, which should be a useful guide for the rapid identification of novel therapeutic agents from chemical database....
To our knowledge, the present work is the first structure-based virtual screening study for new SSRI discovery, which should be a useful gui …
Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases.
Zhao JH, Liu HL, Lin HY, Huang CH, Fang HW, Chen SS, Ho Y, Tsai WB, Chen WY. Zhao JH, et al. Among authors: ho y. Perspect Medicin Chem. 2007 Dec 11;1:39-48. doi: 10.4137/pmc.s212. Perspect Medicin Chem. 2007. PMID: 19812735 Free PMC article.
In this review, we summarize the probable mechanisms of protein conformational diseases in humans and the use of chemical chaperones and inhibitors as potential therapeutic agents against these diseases. Furthermore, recent advanced experimental and theoretical approaches …
In this review, we summarize the probable mechanisms of protein conformational diseases in humans and the use of chemical chaperones and inh …