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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 2
1957 1
1958 2
1959 1
1961 3
1962 3
1963 1
1964 2
1965 1
1967 2
1968 5
1969 4
1970 1
1971 3
1972 1
1973 3
1974 3
1976 2
1977 1
1978 1
1980 3
1981 2
1982 4
1983 2
1984 1
1985 10
1986 7
1987 9
1988 7
1989 14
1990 10
1991 10
1992 7
1993 12
1994 8
1995 7
1996 8
1997 8
1998 13
1999 4
2000 11
2001 9
2002 6
2003 7
2004 8
2005 6
2006 11
2007 5
2008 14
2009 10
2010 7
2011 8
2012 6
2013 6
2014 4
2015 5
2016 3
2017 8
2018 3
2019 3
2020 6
2021 4
2022 1
2023 4
2024 0

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325 results

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Page 1
Structural Analysis of the Histamine H(1) Receptor.
Shiroishi M, Kobayashi T. Shiroishi M, et al. Handb Exp Pharmacol. 2017;241:21-30. doi: 10.1007/164_2016_10. Handb Exp Pharmacol. 2017. PMID: 27826702 Review.
The crystal structure of the human histamine H(1) receptor (H(1)R) has been determined in complex with its inverse agonist doxepin, a first-generation antihistamine. ...
The crystal structure of the human histamine H(1) receptor (H(1)R) has been determined in complex with its inverse agonist doxepin, a …
Rapid identification of histamine-producing bacteria isolated from fish using MALDI-TOF MS.
Uehara S, Kobayashi M, Kimura K, Suzuki J, Sadamasu K. Uehara S, et al. J Food Sci Technol. 2021 Oct;58(10):4055-4061. doi: 10.1007/s13197-021-05092-7. Epub 2021 Apr 18. J Food Sci Technol. 2021. PMID: 34471328 Free PMC article.
Histamine-producing bacteria (HPB) produce histamine from histidine contained in food through the action of histidine decarboxylase. To identify HPB isolated from food, it is necessary to detect histamine produced by the bacteria. In this study, we concurrent
Histamine-producing bacteria (HPB) produce histamine from histidine contained in food through the action of histidine decarbox
A case of eel collagen allergy.
Tamura M, Matsui K, Kobayashi Y, Ogita C, Tsuboi K, Kusakabe M, Azuma K, Abe T, Yoshikawa T, Sekiguchi M, Azuma N, Kitano M, Sano H. Tamura M, et al. Allergol Int. 2018 Jan;67(1):138-140. doi: 10.1016/j.alit.2017.04.012. Epub 2017 Jun 2. Allergol Int. 2018. PMID: 28583315 Free article. No abstract available.
[Roles of histamine in the pathogenesis of bronchial asthma and reevaluation of the clinical usefulness of antihistamines].
Yamauchi K, Shikanai T, Nakamura Y, Kobayashi H, Ogasawara M, Maeyama K. Yamauchi K, et al. Yakugaku Zasshi. 2011 Feb;131(2):185-91. doi: 10.1248/yakushi.131.185. Yakugaku Zasshi. 2011. PMID: 21297359 Free article. Review. Japanese.
Histamine has been reported to play an important role in pathogenesis of bronchial asthma. ...We therefore evaluated its role in allergic airway inflammation with the use of histamine-deficient mice. The results suggested that histamine plays a role in the pr
Histamine has been reported to play an important role in pathogenesis of bronchial asthma. ...We therefore evaluated its role in alle
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo.
Ashina K, Tsubosaka Y, Nakamura T, Omori K, Kobayashi K, Hori M, Ozaki H, Murata T. Ashina K, et al. PLoS One. 2015 Jul 9;10(7):e0132367. doi: 10.1371/journal.pone.0132367. eCollection 2015. PLoS One. 2015. PMID: 26158531 Free PMC article.
Histamine is a mediator of allergic inflammation released mainly from mast cells. ...These were abolished by histamine H1 receptor antagonism. Intravital imaging showed that histamine dilated vasculature, increased blood flow, while it induced hyperpermeabili
Histamine is a mediator of allergic inflammation released mainly from mast cells. ...These were abolished by histamine H1 rece
Search for Substances That Inhibit Histamine Production Using Used Tea Leaves.
Tanahashi N, Azama M, Otsuka M, Ogino F, Maeda R, Hirota T. Tanahashi N, et al. J Food Prot. 2020 Oct 1;83(10):1789-1795. doi: 10.4315/JFP-19-564. J Food Prot. 2020. PMID: 32463868 Free article.
Moreover, because many of the tea components remain in the used tea leaves, these continue to have value, as these leaves exhibit antibacterial action. Furthermore, histamine is produced from histidine via histidine decarboxylase that is produced by microorganisms, with …
Moreover, because many of the tea components remain in the used tea leaves, these continue to have value, as these leaves exhibit antibacter …
Design and synthesis of histamine H(3)/H(4) receptor ligands with a cyclopropane scaffold.
Watanabe M, Kobayashi T, Ito Y, Fukuda H, Yamada S, Arisawa M, Shuto S. Watanabe M, et al. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3630-3633. doi: 10.1016/j.bmcl.2018.10.041. Epub 2018 Oct 26. Bioorg Med Chem Lett. 2018. PMID: 30385161
We previously designed and synthesized a series of histamine analogues with an imidazolylcyclopropane scaffold and identified potent non-selective antagonists for histamine H(3) and H(4) receptor subtypes. ...
We previously designed and synthesized a series of histamine analogues with an imidazolylcyclopropane scaffold and identified potent …
Lead generation from N-[benzyl(4-phenylbutyl)carbamoyl]amino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis.
Kobayashi Y, Uneuchi F, Naruse T, Matsuda D, Okumura-Kitajima L, Kajiyama H, Wada R, Yonemoto Y, Nakano K, Toki H, Kamigaso S, Yamagishi J, Tokura S, Kakinuma H, Kuroda S. Kobayashi Y, et al. Eur J Med Chem. 2023 Nov 15;260:115749. doi: 10.1016/j.ejmech.2023.115749. Epub 2023 Aug 20. Eur J Med Chem. 2023. PMID: 37639822
Compound 18 possessed potent in vitro LPA(1) antagonist activity and exhibited a dose-dependent inhibitory effect against LPA-induced histamine release in mice. Furthermore, 18 significantly suppressed collagen production and skin thickening in a mouse model of bleomycin-i …
Compound 18 possessed potent in vitro LPA(1) antagonist activity and exhibited a dose-dependent inhibitory effect against LPA-induced his
Neuronal control of brain microvessel function.
Kobayashi H, Magnoni MS, Govoni S, Izumi F, Wada A, Trabucchi M. Kobayashi H, et al. Experientia. 1985 Apr 15;41(4):427-34. doi: 10.1007/BF01966140. Experientia. 1985. PMID: 2580734 Review.
325 results