A Novel Quorum-Quenching N-Acylhomoserine Lactone Acylase from Acidovorax sp. Strain MR-S7 Mediates Antibiotic Resistance.
Kusada H, Tamaki H, Kamagata Y, Hanada S, Kimura N.
Kusada H, et al.
Appl Environ Microbiol. 2017 Jun 16;83(13):e00080-17. doi: 10.1128/AEM.00080-17. Print 2017 Jul 1.
Appl Environ Microbiol. 2017.
PMID: 28455333
Free PMC article.
In addition, this enzyme was found to be capable of degrading a wide spectrum of beta-lactams (penicillin G, ampicillin, amoxicillin, carbenicillin, cephalexin, and cefadroxil) by deacylation, clearly indicating that MacQ is a bifunctional enzyme that confers both quorum quenchin …
In addition, this enzyme was found to be capable of degrading a wide spectrum of beta-lactams (penicillin G, ampicillin, amoxicillin, carben …