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Year Number of Results
1988 3
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1994 1
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1998 4
1999 2
2000 2
2001 4
2002 4
2003 5
2004 2
2005 6
2006 9
2007 7
2008 3
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2013 9
2014 4
2015 5
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118 results

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Page 1
Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation.
Seok JH, Kim DH, Kim HJ, Jo HH, Kim EY, Jeong JH, Park YS, Lee SH, Kim DJ, Nam SY, Lee BJ, Lee HJ. Seok JH, et al. J Vet Sci. 2022 Sep;23(5):e74. doi: 10.4142/jvs.22097. J Vet Sci. 2022. PMID: 36174978 Free PMC article.
Hemin increased nuclear factor erythroid-2-related factor 2 (Nrf2) expression, but decreased Keap1 expression. ...In AOM/DSS mice, hemin treatment induced hyperplastic changes in colon tissues, inhibited by EGCG supplementation. ...
Hemin increased nuclear factor erythroid-2-related factor 2 (Nrf2) expression, but decreased Keap1 expression. ...In AOM/DSS mice, …
Hemin as a novel candidate for treating COVID-19 via heme oxygenase-1 induction.
Kim DH, Ahn HS, Go HJ, Kim DY, Kim JH, Lee JB, Park SY, Song CS, Lee SW, Ha SD, Choi C, Choi IS. Kim DH, et al. Sci Rep. 2021 Nov 2;11(1):21462. doi: 10.1038/s41598-021-01054-3. Sci Rep. 2021. PMID: 34728736 Free PMC article.
To confirm whether HO-1 suppresses SARS-CoV-2 infection, we assessed the antiviral activity of hemin, an effective and safe HO-1 inducer, in SARS-CoV-2 infection. We found that treatment with hemin efficiently suppressed SARS-CoV-2 replication (selectivity index: 24 …
To confirm whether HO-1 suppresses SARS-CoV-2 infection, we assessed the antiviral activity of hemin, an effective and safe HO-1 indu …
Hemin, heme oxygenase-1 inducer, attenuates immobilization-induced skeletal muscle atrophy in mice.
Park CH, Ju TJ, Kim YW, Dan JM, Kim JY, Kim YD, Seo JS, Park SY. Park CH, et al. Life Sci. 2013 Apr 9;92(12):740-6. doi: 10.1016/j.lfs.2013.02.008. Epub 2013 Feb 22. Life Sci. 2013. PMID: 23439326
KEY FINDINGS: Immobilization increased HO-1 protein levels in skeletal muscle, which was further increased by hemin treatment. Immobilization induced weight loss and a functional reduction in skeletal muscle, which were attenuated by hemin treatment. Gene expression …
KEY FINDINGS: Immobilization increased HO-1 protein levels in skeletal muscle, which was further increased by hemin treatment. Immobi …
Noncovalent minimal assembly of exogenous histamine with hemin cofactor as a peroxidase-mimicking cooperative catalyst.
Kang B, Park G, Kim SH, Lee D, Oh SS. Kang B, et al. iScience. 2022 Oct 2;25(10):105257. doi: 10.1016/j.isci.2022.105257. eCollection 2022 Oct 21. iScience. 2022. PMID: 36274946 Free PMC article.
Although the molecular weight of hemin-histamine pair is 763, 1.7% of the horseradish peroxidase, cooperative catalysis of two natural molecules exhibits 17.3 times greater catalytic efficiency (17.93 M(-1)s(-1)) and 57.8 times larger specific activity (36.45 mumol/min.mg) …
Although the molecular weight of hemin-histamine pair is 763, 1.7% of the horseradish peroxidase, cooperative catalysis of two natura …
Hemin Reduces HMGB1 Release by UVB in an AMPK/HO-1-dependent Pathway in Human Keratinocytes HaCaT Cells.
Park EJ, Kim YM, Chang KC. Park EJ, et al. Arch Med Res. 2017 Jul;48(5):423-431. doi: 10.1016/j.arcmed.2017.10.007. Epub 2017 Oct 28. Arch Med Res. 2017. PMID: 29089150
HMGB1 release by UVB was significantly reduced by hemin, N-acetyl-cysteine and DPI (NADPH oxidase inhibitor). Hemin increased HO-1 induction followed by phosphorylation of AMPK in a time- and dose-dependent manner. ...Therefore, hemin may be a useful agent fo …
HMGB1 release by UVB was significantly reduced by hemin, N-acetyl-cysteine and DPI (NADPH oxidase inhibitor). Hemin increased …
Nucleic acid detection using G-quadruplex amplification methodologies.
Roembke BT, Nakayama S, Sintim HO. Roembke BT, et al. Methods. 2013 Dec 15;64(3):185-98. doi: 10.1016/j.ymeth.2013.10.003. Epub 2013 Oct 14. Methods. 2013. PMID: 24135042 Free PMC article. Review.
We highlight various strategies, including split G-quadruplex, hemin-G-quadruplex conjugates, molecular beacon G-quadruplex or inhibited G-quadruplex probes. ...
We highlight various strategies, including split G-quadruplex, hemin-G-quadruplex conjugates, molecular beacon G-quadruplex or inhibi …
Microprocessor depends on hemin to recognize the apical loop of primary microRNA.
Nguyen TA, Park J, Dang TL, Choi YG, Kim VN. Nguyen TA, et al. Nucleic Acids Res. 2018 Jun 20;46(11):5726-5736. doi: 10.1093/nar/gky248. Nucleic Acids Res. 2018. PMID: 29750274 Free PMC article.
Furthermore, by generating a DGCR8 mutant cell line and carrying out rescue experiments, we discover that hemin preferentially stimulates the expression of miRNAs possessing the UGU motif, thereby conferring differential regulation of miRNA maturation. Our findings reveal …
Furthermore, by generating a DGCR8 mutant cell line and carrying out rescue experiments, we discover that hemin preferentially stimul …
Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells.
Jang HY, Hong OY, Chung EY, Park KH, Kim JS. Jang HY, et al. Medicina (Kaunas). 2020 May 29;56(6):268. doi: 10.3390/medicina56060268. Medicina (Kaunas). 2020. PMID: 32485912 Free PMC article.
Hemin enhanced HO-1 expression through the activation of c-Jun N-terminal kinases (JNK) signaling pathway. Hemin also induced activation of Nrf2, a major transcription factor of HO-1 expression. ...
Hemin enhanced HO-1 expression through the activation of c-Jun N-terminal kinases (JNK) signaling pathway. Hemin also induced …
Electron Hopping Across Hemin-Doped Serum Albumin Mats on Centimeter-Length Scales.
Amdursky N, Wang X, Meredith P, Riley DJ, Payne DJ, Bradley DDC, Stevens MM. Amdursky N, et al. Adv Mater. 2017 Jul;29(27):1700810. doi: 10.1002/adma.201700810. Epub 2017 May 31. Adv Mater. 2017. PMID: 28561988 Free PMC article.
In particular, this study focuses on how doping the protein mat with hemin improves charge-transport. It is demonstrated that doping can increase conductivity 40-fold via electron hopping between adjacent hemin molecules, resulting in the highest measured conductanc …
In particular, this study focuses on how doping the protein mat with hemin improves charge-transport. It is demonstrated that doping …
Hemin improves insulin sensitivity in skeletal muscle in high fat-fed mice.
Ju TJ, Kwon WY, Kim YW, Kim JY, Kim YD, Lee IK, Park SY. Ju TJ, et al. J Pharmacol Sci. 2014;126(2):115-25. doi: 10.1254/jphs.14003fp. J Pharmacol Sci. 2014. PMID: 25341564 Free article.
A four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels of insulin and lipid, which were reduced by hemin. High-fat diet reduced whole body glucose uptake, which were increased by hemin. Insulin-stimulated hepatic glucose producti …
A four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels of insulin and lipid, which were reduced by h …
118 results