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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1958 1
1964 1
1965 1
1967 2
1968 3
1969 7
1970 7
1971 9
1972 4
1973 5
1974 5
1975 4
1976 2
1977 11
1978 10
1979 11
1980 8
1981 13
1982 9
1983 12
1984 11
1985 8
1986 11
1987 19
1988 18
1989 30
1990 43
1991 37
1992 33
1993 39
1994 47
1995 48
1996 47
1997 61
1998 66
1999 75
2000 89
2001 88
2002 113
2003 109
2004 104
2005 137
2006 159
2007 134
2008 162
2009 151
2010 136
2011 126
2012 150
2013 170
2014 216
2015 212
2016 195
2017 186
2018 190
2019 216
2020 218
2021 199
2022 186
2023 181
2024 56

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4,108 results

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Page 1
The Hamilton Anxiety Scale: reliability, validity and sensitivity to change in anxiety and depressive disorders.
Maier W, Buller R, Philipp M, Heuser I. Maier W, et al. J Affect Disord. 1988 Jan-Feb;14(1):61-8. doi: 10.1016/0165-0327(88)90072-9. J Affect Disord. 1988. PMID: 2963053 Clinical Trial.
The reliability and the concurrent validity of the HAM-A and its subscales proved to be sufficient. Internal validity tested by latent structure analysis was insufficient. ...The applicability of the HAM-A in anxiolytic treatment studies is therefore limited. More s …
The reliability and the concurrent validity of the HAM-A and its subscales proved to be sufficient. Internal validity tested by laten …
Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial.
Kanes S, Colquhoun H, Gunduz-Bruce H, Raines S, Arnold R, Schacterle A, Doherty J, Epperson CN, Deligiannidis KM, Riesenberg R, Hoffmann E, Rubinow D, Jonas J, Paul S, Meltzer-Brody S. Kanes S, et al. Lancet. 2017 Jul 29;390(10093):480-489. doi: 10.1016/S0140-6736(17)31264-3. Epub 2017 Jun 12. Lancet. 2017. PMID: 28619476 Clinical Trial.
The primary efficacy endpoint was the change from baseline in the 17-item HAM-D total score at 60 h, assessed in all randomised patients who started infusion of study drug or placebo and who had a completed baseline HAM-D assessment and at least one post-baseline …
The primary efficacy endpoint was the change from baseline in the 17-item HAM-D total score at 60 h, assessed in all randomised patie …
A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder.
Woelk H, Schläfke S. Woelk H, et al. Phytomedicine. 2010 Feb;17(2):94-9. doi: 10.1016/j.phymed.2009.10.006. Epub 2009 Dec 3. Phytomedicine. 2010. PMID: 19962288 Clinical Trial.
The primary target variable was the change in the Hamilton Anxiety Rating Scale (HAM-A-total score) as an objective measurement of the severity of anxiety between baseline and week 6. ...During the active treatment period, the two HAM-A subscores "somatic anxiety" ( …
The primary target variable was the change in the Hamilton Anxiety Rating Scale (HAM-A-total score) as an objective measurement of th …
Vortioxetine in patients with major depressive disorder and high levels of anxiety symptoms: An updated analysis of efficacy and tolerability.
Adair M, Christensen MC, Florea I, Loft H, Fagiolini A. Adair M, et al. J Affect Disord. 2023 May 1;328:345-354. doi: 10.1016/j.jad.2023.01.074. Epub 2023 Jan 26. J Affect Disord. 2023. PMID: 36708956 Free article. Clinical Trial.
METHODS: The efficacy and tolerability of vortioxetine 5-20 mg/day were assessed in patients with MDD and high levels of anxiety symptoms (Hamilton Anxiety Rating Scale [HAM-A] total score 20) using pooled data from four randomized, fixed-dose, placebo-controlled studies ( …
METHODS: The efficacy and tolerability of vortioxetine 5-20 mg/day were assessed in patients with MDD and high levels of anxiety symptoms (H …
Gepirone extended-release in the treatment of adult outpatients with major depressive disorder: a double-blind, randomized, placebo-controlled, parallel-group study.
Bielski RJ, Cunningham L, Horrigan JP, Londborg PD, Smith WT, Weiss K. Bielski RJ, et al. J Clin Psychiatry. 2008 Apr;69(4):571-7. doi: 10.4088/jcp.v69n0408. J Clin Psychiatry. 2008. PMID: 18373383 Clinical Trial.
The primary outcome measure was baseline-to-endpoint mean change in HAM-D(17) total score. Secondary outcome measures included the 28-item version of the HAM-D, HAM-D depressed mood (item 1), Bech Six-Item Scale, Montgomery-Asberg Depression Rating Scale, and …
The primary outcome measure was baseline-to-endpoint mean change in HAM-D(17) total score. Secondary outcome measures included the 28 …
Brexanolone for postpartum depression.
Hutcherson TC, Cieri-Hutcherson NE, Gosciak MF. Hutcherson TC, et al. Am J Health Syst Pharm. 2020 Feb 19;77(5):336-345. doi: 10.1093/ajhp/zxz333. Am J Health Syst Pharm. 2020. PMID: 32073124 Review.
All studies demonstrated statistical improvement in HAM-D scores from baseline with brexanolone vs placebo use at the end of infusions (ie, hour 60). Results with regard to sustained HAM-D score improvements were mixed in the RCTs at 30-day follow-up. ...
All studies demonstrated statistical improvement in HAM-D scores from baseline with brexanolone vs placebo use at the end of infusion …
Therapeutic strategies in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Nakamura T, Nishiura Y, Eguchi K. Nakamura T, et al. Cent Nerv Syst Agents Med Chem. 2009 Jun;9(2):137-49. doi: 10.2174/187152409788452090. Cent Nerv Syst Agents Med Chem. 2009. PMID: 20021347 Review.
However, there are still many of problems, such as insufficient effects, side effects and expensive costs in long-term treatments, etc., in these treatments. Therefore, an ideal therapeutic strategy against HAM/TSP is still not established yet. Although only a small …
However, there are still many of problems, such as insufficient effects, side effects and expensive costs in long-term treatments, etc., in …
[Developing novel treatments for HTLV-1-associated myelopathy (HAM) by investigating molecular pathomechanisms].
Araya N, Sato T, Coler-Reilly A, Yagishita N, Yamano Y. Araya N, et al. Nihon Rinsho Meneki Gakkai Kaishi. 2016;39(3):207-12. doi: 10.2177/jsci.39.207. Nihon Rinsho Meneki Gakkai Kaishi. 2016. PMID: 27320936 Free article. Review. Japanese.
Recently, the authors and others have determined that HTLV-1 in HAM/TSP patients primarily infects T cells expressing the chemokine receptor CCR4. The authors postulated that HTLV-1 causes these T cells to develop Th1-like functions that are critical for the pathogenesis o …
Recently, the authors and others have determined that HTLV-1 in HAM/TSP patients primarily infects T cells expressing the chemokine r …
Assessing full remission.
McIntyre R, Kennedy S, Bagby RM, Bakish D. McIntyre R, et al. J Psychiatry Neurosci. 2002 Jul;27(4):235-9. J Psychiatry Neurosci. 2002. PMID: 12174732 Free PMC article.
A shortened form of the HAM-D17 with cut-off scores for full remission would offer a useful tool that physicians could readily employ in clinical practice. ...A score of 3 or less on the Toronto HAM-D7 was found to correlate with the 17-item HAM-D definition …
A shortened form of the HAM-D17 with cut-off scores for full remission would offer a useful tool that physicians could readily employ …
Translating the HAM-D into the MADRS and vice versa with equipercentile linking.
Leucht S, Fennema H, Engel RR, Kaspers-Janssen M, Szegedi A. Leucht S, et al. J Affect Disord. 2018 Jan 15;226:326-331. doi: 10.1016/j.jad.2017.09.042. Epub 2017 Sep 27. J Affect Disord. 2018. PMID: 29031182
An absolute HAM-D improvement of 10, 20, 25 points corresponded to a MADRS improvement of 12, 26, and 34. A percentage improvement from baseline of the HAM-D was approximately the same as a percentage improvement on the MADRS. ...
An absolute HAM-D improvement of 10, 20, 25 points corresponded to a MADRS improvement of 12, 26, and 34. A percentage improvement fr …
4,108 results