Identification and validation of microtubule depolymerizing agent, CYT997, as a potential drug candidate for hepatocellular carcinoma.
Ahmad F, Ma L, Wei W, Liu Y, Hakim I, Daugherty A, Mujahid S, Radin AA, Chua MS, So S.
Ahmad F, et al.
Liver Int. 2023 Dec;43(12):2794-2807. doi: 10.1111/liv.15756. Epub 2023 Oct 13.
Liver Int. 2023.
PMID: 37833852
Immunohistochemistry confirmed the down-regulation of GPC3, c-Myc, and Ki-67, supporting its anti-proliferative effect. CONCLUSION: CYT997 is a potentially efficacious and non-toxic drug candidate for HCC therapy. ...
Immunohistochemistry confirmed the down-regulation of GPC3, c-Myc, and Ki-67, supporting its anti-proliferative effect. CONCLUSION: C …