Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 2
2009 6
2010 1
2013 1
2015 3
2016 1
2018 1
2020 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

15 results

Results by year

Filters applied: . Clear all
Page 1
Tegillarca granosa extract Haishengsu inhibits tumor activity via a mitochondrial-mediated apoptotic pathway.
Chen XH, Han YT, Ye JL, Chang ZS, Wang CB, Chen SG. Chen XH, et al. Mol Med Rep. 2018 May;17(5):6828-6834. doi: 10.3892/mmr.2018.8654. Epub 2018 Mar 1. Mol Med Rep. 2018. PMID: 29512751
Haishengsu (HSS) is an active natural extract isolated from Tegillarca granosa, which has previously been demonstrated to inhibit the proliferation of several types of cancer cells in vitro. ...
Haishengsu (HSS) is an active natural extract isolated from Tegillarca granosa, which has previously been demonstrated to inhibit the …
Effect of haishengsu as an adjunct therapy for patients with advanced renal cell cancer: a randomized and placebo-controlled clinical trial.
Liu JZ, Chen SG, Zhang B, Wang CB, Zhao XW, Li GY, Wang LX. Liu JZ, et al. J Altern Complement Med. 2009 Oct;15(10):1127-30. doi: 10.1089/acm.2009.0260. J Altern Complement Med. 2009. PMID: 19821717 Clinical Trial.

The remission rate of cancer in the Haishengsu group was higher than in the control group (51.9% and 21.4%, p < 0.01). CONCLUSIONS: Addition of Haishengsu to the conventional immunotherapy is associated with an increased remission rate in patients with advanced r

…

The remission rate of cancer in the Haishengsu group was higher than in the control group (51.9% and 21.4%, p < 0.01). CONCLUSIONS

…
Haishengsu as an adjunct therapy to conventional chemotherapy in patients with non-small cell lung cancer: a pilot randomized and placebo-controlled clinical trial.
Li GY, Yu XM, Zhang HW, Zhang B, Wang CB, Xin YC, Yang CZ, Zhou RX, Wang LX. Li GY, et al. Complement Ther Med. 2009 Jan;17(1):51-5. doi: 10.1016/j.ctim.2008.10.002. Epub 2008 Dec 3. Complement Ther Med. 2009. PMID: 19114229 Clinical Trial.
OBJECTIVE: To investigate the effect of Haishengsu, an extract from Tegillarca granosa, on non-small cell lung cancer as an adjunct to conventional chemotherapy. ...CONCLUSIONS: This study suggests that Haishengsu may be an effective adjunct therapy to the conventio …
OBJECTIVE: To investigate the effect of Haishengsu, an extract from Tegillarca granosa, on non-small cell lung cancer as an adjunct t …
Tegillarca granosa extract Haishengsu induces apoptosis in human hepatocellular carcinoma cell line BEL-7402 via Fas-signaling pathways.
Chen X, Han Y, Zhan S, Wang C, Chen S. Chen X, et al. Cell Biochem Biophys. 2015 Mar;71(2):837-44. doi: 10.1007/s12013-014-0271-3. Cell Biochem Biophys. 2015. PMID: 25257131
This study was designed to investigate the apoptosis-inducing properties of Tegillarca granosa extract Haishengsu (HSS) in human hepatocellular carcinoma cell line BEL-7402. ...
This study was designed to investigate the apoptosis-inducing properties of Tegillarca granosa extract Haishengsu (HSS) in human hepa …
[Mechanism Inducing the HL-60 Cell Differentiation by Haishengsu Tegillarca Granosa Extract via Targeting ULK1 Protein].
Zhong M, Su QH, Xu L. Zhong M, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020 Feb;28(1):141-145. doi: 10.19746/j.cnki.issn.1009-2137.2020.01.024. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2020. PMID: 32027267 Chinese.
RESULTS: After cultured for 48 and 72 h the cell proliferation rates of HL-60 in Haishengsu 100 and 1000 mg/L groups were significantly lower than those of ATRA 5 mumol/L group and Haishengsu 10 mg/L group and control group (P<0.05). After 72 h, the levels of CD1 …
RESULTS: After cultured for 48 and 72 h the cell proliferation rates of HL-60 in Haishengsu 100 and 1000 mg/L groups were significant …
Marine drug Haishengsu increases chemosensitivity to conventional chemotherapy and improves quality of life in patients with acute leukemia.
Li GY, Zhang L, Liu JZ, Chen SG, Xiao TW, Liu GZ, Wang JX, Wang LX, Hou M. Li GY, et al. Biomed Pharmacother. 2016 Jul;81:160-165. doi: 10.1016/j.biopha.2016.04.005. Epub 2016 Apr 16. Biomed Pharmacother. 2016. PMID: 27261590 Clinical Trial.
BACKGROUND: Pharmacological management of acute leukemia remains a challenge. A seashell protein Haishengsu (HSS) has been found to exert anticancer activities in recent in vitro studies. ...
BACKGROUND: Pharmacological management of acute leukemia remains a challenge. A seashell protein Haishengsu (HSS) has been found to e …
Tegillarca granosa extract Haishengsu (HSS) suppresses expression of mdr1, BCR/ABL and sorcin in drug-resistant K562/ADM tumors in mice.
Li GY, Liu JZ, Zhang B, Yang M, Chen SG, Hou M, Wang LX. Li GY, et al. Adv Med Sci. 2013;58(1):112-7. doi: 10.2478/v10039-012-0069-8. Adv Med Sci. 2013. PMID: 23729583
PURPOSE: To evaluate the effect of Haishengsu (HSS), a protein extract from Tegillarca granosa, on multidrug-resistance genes mdr1, BCR/ABL and sorcin in transplanted tumors. ...The pro-apoptotic effect of Haishengsu may be related to a reduced expression of multidr …
PURPOSE: To evaluate the effect of Haishengsu (HSS), a protein extract from Tegillarca granosa, on multidrug-resistance genes mdr1, B …
Effect of Haishengsu on transplanted K562 and drug-resistant K562/ADM tumors: an experimental study.
Liu JZ, Yang M, Li DP, Zhang B, Chen SG, Wang CB, Li GY, Wang LX. Liu JZ, et al. Clin Invest Med. 2009 Apr 1;32(2):E117-23. doi: 10.25011/cim.v32i2.6029. Clin Invest Med. 2009. PMID: 19331800
PURPOSE: To evaluate the effect of Haishengsu (HSS) on transplanted K562 and drug-resistant K562/ADM tumors. ...Pathological examination of tumour tissues from HSS-treated animals showed extensive necrosis and bleeding. CONCLUSIONS: Haishengsu inhibits the growth of …
PURPOSE: To evaluate the effect of Haishengsu (HSS) on transplanted K562 and drug-resistant K562/ADM tumors. ...Pathological examinat …
The impact of Tegillarca granosa extract haishengsu on HL-60 cell.
Wang J, Wei L, Han Y, Qin D, Yang Q, Ju X. Wang J, et al. Open Med (Wars). 2015 Aug 3;10(1):329-334. doi: 10.1515/med-2015-0048. eCollection 2015. Open Med (Wars). 2015. PMID: 28352714 Free PMC article.
Haishengsu (Hss) is a purified protein from Tegillarca granosa that has been used as a traditional Chinese medicine to treat cancer for more than a century. In this study, we observed the impact of Haishengsu (Hss) on the proliferation and differentiation of HL-60 c …
Haishengsu (Hss) is a purified protein from Tegillarca granosa that has been used as a traditional Chinese medicine to treat cancer f …
Tegillarca granosa extract Haishengsu inhibits the expression of P-glycoprotein and induces apoptosis in drug-resistant K562/ADM cells.
Li GY, Liu JZ, Chen SG, Zhang B, Wang CB, Wang LX. Li GY, et al. Pharm Biol. 2010 May;48(5):529-33. doi: 10.3109/13880200903176620. Pharm Biol. 2010. PMID: 20645795
This study was designed to investigate the effect and molecular mechanisms of Haishengsu (HSS), a protein extract from a shellfish Tegillarca granosaL., on a drug resistant leukemia cell line. ...
This study was designed to investigate the effect and molecular mechanisms of Haishengsu (HSS), a protein extract from a shellfish Te …
15 results