guohe chi - Search Results

Year	Number of Results
2022	6
2023	7
2024	4

1

Gut microbiota mediates the pharmacokinetics of Zhi-zi-chi decoction for the personalized treatment of depression.

Gao FY, Chen XF, Cui LX, Zhai YJ, Liu JL, Gao CC, Fang YC, Huang TH, Wen J, Zhou TT. Gao FY, et al. J Ethnopharmacol. 2023 Feb 10;302(Pt B):115934. doi: 10.1016/j.jep.2022.115934. Epub 2022 Nov 19. J Ethnopharmacol. 2023. PMID: 36414216 Free article.

ETHNOPHARMACOLOGICAL RELEVANCE: Zhi-zi-chi decoction (ZZCD), from "Treatise on Febrile Diseases", is a typical traditional Chinese medicine herb pair, which consists of Gardeniae Fructus (GF) and Semen Sojae Praeparatu (SSP). ...

ETHNOPHARMACOLOGICAL RELEVANCE: Zhi-zi-chi decoction (ZZCD), from "Treatise on Febrile Diseases", is a typical traditional Chinese me …

2

Discovery of Novel 7-Hydroxy-5-oxo-4,5-dihydrothieno[3,2-b]pyridine-6-carboxamide Derivatives with Potent and Selective Antifungal Activity against Cryptococcus Species.

Li L, Wu H, Zhu S, Ji Z, Chi X, Xie F, Hao Y, Lu H, Yang F, Yan L, Zhang D, Jiang Y, Ni T. Li L, et al. J Med Chem. 2022 Aug 25;65(16):11257-11269. doi: 10.1021/acs.jmedchem.2c00794. Epub 2022 Aug 3. J Med Chem. 2022. PMID: 35922963

3

Design, synthesis, and in vitro evaluation of novel antifungal triazoles containing substituted 1,2,3-triazole-methoxyl side chains.

Xie F, Hao Y, Bao J, Liu J, Liu Y, Wang R, Chi X, Chai X, Wang T, Yu S, Jin Y, Yan L, Zhang D, Ni T. Xie F, et al. Bioorg Chem. 2022 Dec;129:106216. doi: 10.1016/j.bioorg.2022.106216. Epub 2022 Oct 21. Bioorg Chem. 2022. PMID: 36283177

4

Discovery of novel triazoles containing benzyloxy phenyl isoxazole side chain with potent and broad-spectrum antifungal activity.

Chi X, Xie F, Li L, Hao Y, Wu H, Li X, Xia G, Yan L, Zhang D, Jiang Y, Ni T. Chi X, et al. Bioorg Chem. 2023 Aug;137:106572. doi: 10.1016/j.bioorg.2023.106572. Epub 2023 Apr 28. Bioorg Chem. 2023. PMID: 37156136

5

Discovery of Novel Thiosemicarbazides Containing 1,3,5-Triazines Derivatives as Potential Synergists against Fluconazole-Resistant Candida albicans.

Xie F, Hao Y, Liu J, Bao J, Ni T, Liu Y, Chi X, Wang T, Yu S, Jin Y, Li L, Zhang D, Yan L. Xie F, et al. Pharmaceutics. 2022 Oct 29;14(11):2334. doi: 10.3390/pharmaceutics14112334. Pharmaceutics. 2022. PMID: 36365153 Free PMC article.

6

Novel antifungal triazoles with alkynyl-methoxyl side chains: Design, synthesis, and biological activity evaluation.

Xie F, Hao Y, Li L, Wang R, Bao J, Chi X, Monk BC, Wang T, Yu S, Jin Y, Zhang D, Ni T, Yan L. Xie F, et al. Eur J Med Chem. 2023 Sep 5;257:115506. doi: 10.1016/j.ejmech.2023.115506. Epub 2023 May 18. Eur J Med Chem. 2023. PMID: 37216811

7

Design, synthesis, and evaluation of novel tetrazoles featuring isoxazole moiety as highly selective antifungal agents.

Ni T, Chi X, Xie F, Li L, Wu H, Hao Y, Wang X, Zhang D, Jiang Y. Ni T, et al. Eur J Med Chem. 2023 Jan 15;246:115007. doi: 10.1016/j.ejmech.2022.115007. Epub 2022 Dec 7. Eur J Med Chem. 2023. PMID: 36502579

8

Discovery of Novel Orally Bioavailable Triazoles with Potent and Broad-Spectrum Antifungal Activity In Vitro and In Vivo.

Ni T, Xie F, Hao Y, Li L, Zhu S, Wu H, Chi X, Yan L, Jiang Y, Zhang D. Ni T, et al. J Med Chem. 2022 Dec 22;65(24):16665-16678. doi: 10.1021/acs.jmedchem.2c01497. Epub 2022 Dec 13. J Med Chem. 2022. PMID: 36512715

9

Discovery of a Novel Potent Tetrazole Antifungal Candidate with High Selectivity and Broad Spectrum.

Ni T, Hao Y, Ding Z, Chi X, Xie F, Wang R, Bao J, Yan L, Li L, Wang T, Zhang D, Jiang Y. Ni T, et al. J Med Chem. 2024 Apr 25;67(8):6238-6252. doi: 10.1021/acs.jmedchem.3c02188. Epub 2024 Apr 10. J Med Chem. 2024. PMID: 38598688

10

Design, Synthesis and Structure-Activity Relationship Studies of Nicotinamide Derivatives as Potent Antifungal Agents by Disrupting Cell Wall.

Ni T, Xie F, Li L, Hao Y, Chi X, Yan L, Zhang D, Jiang Y, Lv Q. Ni T, et al. Molecules. 2023 Jan 23;28(3):1135. doi: 10.3390/molecules28031135. Molecules. 2023. PMID: 36770802 Free PMC article.

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