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Year Number of Results
1996 2
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1999 1
2001 2
2005 1
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2009 4
2010 1
2011 1
2012 3
2013 3
2014 4
2015 1
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31 results

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Page 1
Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue.
Dion-Albert L, Cadoret A, Doney E, Kaufmann FN, Dudek KA, Daigle B, Parise LF, Cathomas F, Samba N, Hudson N, Lebel M; Signature Consortium; Campbell M, Turecki G, Mechawar N, Menard C. Dion-Albert L, et al. Nat Commun. 2022 Jan 10;13(1):164. doi: 10.1038/s41467-021-27604-x. Nat Commun. 2022. PMID: 35013188 Free PMC article.
Here, we report that chronic social and subchronic variable stress promotes blood-brain barrier (BBB) alterations in mood-related brain regions of female mice. Targeted disruption of the BBB in the female prefrontal cortex (PFC) induces anxiety- and depression-like behavio …
Here, we report that chronic social and subchronic variable stress promotes blood-brain barrier (BBB) alterations in mood-related brain regi …
Large-scale brain correlates of sweet versus cocaine reward in rats.
Lenoir M, Navailles S, Vandaele Y, Vouillac-Mendoza C, Guillem K, Ahmed SH. Lenoir M, et al. Eur J Neurosci. 2023 Feb;57(3):423-439. doi: 10.1111/ejn.15879. Epub 2022 Dec 13. Eur J Neurosci. 2023. PMID: 36453530
They included regions involved in taste processing (i.e., anterior gustatory cortex) and also regions involved in processing reward delay and intertemporal choice (i.e., some components of the septohippocampal system and its connections with the lateral habenula)....
They included regions involved in taste processing (i.e., anterior gustatory cortex) and also regions involved in processing reward d …
Neuronal representation of individual heroin choices in the orbitofrontal cortex.
Guillem K, Brenot V, Durand A, Ahmed SH. Guillem K, et al. Addict Biol. 2018 May;23(3):880-888. doi: 10.1111/adb.12536. Epub 2017 Jul 13. Addict Biol. 2018. PMID: 28703355
Drug addiction is a harmful preference for drug use over and at the expense of other non-drug-related activities. We previously identified in the rat orbitofrontal cortex (OFC) a mechanism that influences individual preferences between cocaine use and an alternative action …
Drug addiction is a harmful preference for drug use over and at the expense of other non-drug-related activities. We previously identified i …
Reorganization of theta phase-locking in the orbitofrontal cortex drives cocaine choice under the influence.
Guillem K, Ahmed SH. Guillem K, et al. Sci Rep. 2020 May 15;10(1):8041. doi: 10.1038/s41598-020-64962-w. Sci Rep. 2020. PMID: 32415278 Free PMC article.
Cortical theta oscillations of neuronal activity are a fundamental mechanism driving goal-directed behavior. We previously identified in the rat orbitofrontal cortex (OFC) a neuronal correlate of individual preferences between cocaine use and an alternative nondrug reward …
Cortical theta oscillations of neuronal activity are a fundamental mechanism driving goal-directed behavior. We previously identified in the …
Preference for Cocaine is Represented in the Orbitofrontal Cortex by an Increased Proportion of Cocaine Use-Coding Neurons.
Guillem K, Ahmed SH. Guillem K, et al. Cereb Cortex. 2018 Mar 1;28(3):819-832. doi: 10.1093/cercor/bhw398. Cereb Cortex. 2018. PMID: 28057724
Cocaine addiction is a harmful preference for drug use over and at the expense of other nondrug-related activities. Here we identify in the rat orbitofrontal cortex (OFC) a mechanism that explains individual preferences between cocaine use and an alternative, nondrug actio …
Cocaine addiction is a harmful preference for drug use over and at the expense of other nondrug-related activities. Here we identify in the …
Orbitofrontal and insular cortex: neural responses to cocaine-associated cues and cocaine self-administration.
Guillem K, Kravitz AV, Moorman DE, Peoples LL. Guillem K, et al. Synapse. 2010 Jan;64(1):1-13. doi: 10.1002/syn.20698. Synapse. 2010. PMID: 19725114
Based on neuro-imaging studies in cocaine-addicted humans, it is hypothesized that increases in neural activity within several regions of the prefrontal cortex contribute to cue-induced cocaine seeking and cocaine-induced compulsive drug self-administration. ...
Based on neuro-imaging studies in cocaine-addicted humans, it is hypothesized that increases in neural activity within several regions of th …
Nicotinic acetylcholine receptor beta2 subunits in the medial prefrontal cortex control attention.
Guillem K, Bloem B, Poorthuis RB, Loos M, Smit AB, Maskos U, Spijker S, Mansvelder HD. Guillem K, et al. Science. 2011 Aug 12;333(6044):888-91. doi: 10.1126/science.1207079. Science. 2011. PMID: 21836018
Acetylcholine (ACh) levels in the brain diminish with aging, and nicotinic ACh receptor (nAChR) stimulation is known to enhance cognitive performance. The prefrontal cortex (PFC) is involved in a range of cognitive functions and is thought to mediate attentional focus. ...
Acetylcholine (ACh) levels in the brain diminish with aging, and nicotinic ACh receptor (nAChR) stimulation is known to enhance cognitive pe …
A neuronal population code for resemblance between drug and nondrug reward outcomes in the orbitofrontal cortex.
Guillem K, Ahmed SH. Guillem K, et al. Brain Struct Funct. 2019 Mar;224(2):883-890. doi: 10.1007/s00429-018-1809-8. Epub 2018 Dec 11. Brain Struct Funct. 2019. PMID: 30539287
The orbitofrontal cortex (OFC) is implicated in choice and decision-making in both human and non-human animals. ...
The orbitofrontal cortex (OFC) is implicated in choice and decision-making in both human and non-human animals. ...
fMRI response in the medial prefrontal cortex predicts cocaine but not sucrose self-administration history.
Lu H, Chefer S, Kurup PK, Guillem K, Vaupel DB, Ross TJ, Moore A, Yang Y, Peoples LL, Stein EA. Lu H, et al. Neuroimage. 2012 Sep;62(3):1857-66. doi: 10.1016/j.neuroimage.2012.05.076. Epub 2012 Jun 1. Neuroimage. 2012. PMID: 22664568 Free PMC article.
A strong positive fMRI response, as measured by fractional cerebral blood volume changes relative to baseline (CBV%), was seen in the sedentary control group in such cortico-limbic regions as medial prefrontal cortex and anterior cingulate cortex. In contrast, both …
A strong positive fMRI response, as measured by fractional cerebral blood volume changes relative to baseline (CBV%), was seen in the sedent …
31 results