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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1975 3
1977 2
1982 1
1983 2
1984 6
1985 1
1986 3
1987 4
1988 1
1989 11
1990 11
1991 9
1992 11
1993 18
1994 25
1995 32
1996 28
1997 33
1998 45
1999 39
2000 42
2001 68
2002 79
2003 92
2004 125
2005 194
2006 213
2007 264
2008 311
2009 389
2010 499
2011 582
2012 783
2013 951
2014 1170
2015 1362
2016 1584
2017 1831
2018 2268
2019 2727
2020 3505
2021 4438
2022 5571
2023 5971
2024 2677

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34,015 results

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Page 1
CRISPR/Cas9 in Genome Editing and Beyond.
Wang H, La Russa M, Qi LS. Wang H, et al. Annu Rev Biochem. 2016 Jun 2;85:227-64. doi: 10.1146/annurev-biochem-060815-014607. Epub 2016 Apr 25. Annu Rev Biochem. 2016. PMID: 27145843 Review.
The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered regularly interspaced short palindromic repeats) bacterial immune systems, is emerging as a powerful tool for engineering the genome in diverse organisms. As an RNA-guided DNA endonuclea …
The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered regularly interspaced short palindromic repeats) bact …
Parathyroidectomy.
Wang Y, Ladie DE. Wang Y, et al. 2022 Sep 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2022 Sep 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 33085421 Free Books & Documents.
With the development of the preoperative localization technique, the minimally invasive surgery using the radio-guided technique, ultrasound imaging, high-resolution endoscopic technique, rapid intraoperative parathyroid hormone (IOPTH) monitoring has been used by many sur …
With the development of the preoperative localization technique, the minimally invasive surgery using the radio-guided technique, ult …
The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Liu L, Li X, Ma J, Li Z, You L, Wang J, Wang M, Zhang X, Wang Y. Liu L, et al. Cell. 2017 Aug 10;170(4):714-726.e10. doi: 10.1016/j.cell.2017.06.050. Epub 2017 Jul 27. Cell. 2017. PMID: 28757251 Free article.
Cas13a, a type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, degrades invasive RNAs targeted by CRISPR RNA (crRNA) and has potential applications in RNA technology. ...The crRNA-target RNA duplex binds in a positively charged central channel of the nuclease (NUC) lobe, and …
Cas13a, a type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, degrades invasive RNAs targeted by CRISPR RNA (crRNA) and has potential a …
Effect of pharmacogenomics testing guiding on clinical outcomes in major depressive disorder: a systematic review and meta-analysis of RCT.
Wang X, Wang C, Zhang Y, An Z. Wang X, et al. BMC Psychiatry. 2023 May 12;23(1):334. doi: 10.1186/s12888-023-04756-2. BMC Psychiatry. 2023. PMID: 37173736 Free PMC article.
BACKGROUND: Pharmacogenomic testing guided treatment have been developed to guide drug selection or conversion in major depressive disorder patients. ...CONCLUSION: Patients with major depressive disorder may benefit from pharmacogenomic testing guided treatm …
BACKGROUND: Pharmacogenomic testing guided treatment have been developed to guide drug selection or conversion in major depres …
A Microbial Community Cultured in Gradient Hydrogel for Investigating Gut Microbiome-Drug Interaction and Guiding Therapeutic Decisions.
Zheng DW, Qiao JY, Ma JC, An JX, Yang CH, Zhang Y, Cheng Q, Rao ZY, Zeng SM, Wang L, Zhang XZ. Zheng DW, et al. Adv Mater. 2023 Jun;35(22):e2300977. doi: 10.1002/adma.202300977. Epub 2023 Apr 21. Adv Mater. 2023. PMID: 37029611
Examination of various clinical and experimental drugs by EM reveales that the gut microbiota affects drug efficacy through three pathways: immunological effects, bioaccumulation, and drug metabolism. Guided by discovered mechanisms, custom-tailored strategies are adopted …
Examination of various clinical and experimental drugs by EM reveales that the gut microbiota affects drug efficacy through three pathways: …
Bacterial genome engineering using CRISPR RNA-guided transposases.
Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang H, Sternberg SH. Gelsinger DR, et al. bioRxiv [Preprint]. 2023 Mar 21:2023.03.18.533263. doi: 10.1101/2023.03.18.533263. bioRxiv. 2023. PMID: 36993567 Free PMC article. Updated. Preprint.
CRISPR-associated transposons (CASTs) have the potential to transform the technology landscape for kilobase-scale genome engineering, by virtue of their ability to integrate large genetic payloads with high accuracy, easy programmability, and no requirement for homologous recombi …
CRISPR-associated transposons (CASTs) have the potential to transform the technology landscape for kilobase-scale genome engineering, by vir …
A systematic review of the accuracy of digital surgical guides for dental implantation.
Shi Y, Wang J, Ma C, Shen J, Dong X, Lin D. Shi Y, et al. Int J Implant Dent. 2023 Oct 25;9(1):38. doi: 10.1186/s40729-023-00507-w. Int J Implant Dent. 2023. PMID: 37875645 Free PMC article. Review.
METHODS: A literature search related to accuracy of surgical guides for dental implantation was performed in Web of Science and PubMed. ...Milling exhibited higher in vivo accuracy of guides than 3d-printing, though further data support was needed. Design of fixatio …
METHODS: A literature search related to accuracy of surgical guides for dental implantation was performed in Web of Science and PubMe …
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting.
Wei J, Lotfy P, Faizi K, Baungaard S, Gibson E, Wang E, Slabodkin H, Kinnaman E, Chandrasekaran S, Kitano H, Durrant MG, Duffy CV, Pawluk A, Hsu PD, Konermann S. Wei J, et al. Cell Syst. 2023 Dec 20;14(12):1087-1102.e13. doi: 10.1016/j.cels.2023.11.006. Epub 2023 Dec 12. Cell Syst. 2023. PMID: 38091991
Here, we quantified the performance of over 127,000 RfxCas13d (CasRx) guide RNAs and systematically evaluated seven machine learning models to build a guide efficiency prediction algorithm orthogonally validated across multiple human cell types. ...Our Cas13d gui …
Here, we quantified the performance of over 127,000 RfxCas13d (CasRx) guide RNAs and systematically evaluated seven machine learning …
Comparison of four CAD-CAM guides for preparing guiding planes of removable partial dentures.
Bai H, Ye H, Chen H, Wang Y, Zhou Y, Sun Y. Bai H, et al. Comput Biol Med. 2022 Jul;146:105564. doi: 10.1016/j.compbiomed.2022.105564. Epub 2022 Apr 29. Comput Biol Med. 2022. PMID: 35569334 Free article.
BACKGROUND AND OBJECTIVE: To evaluate the effect of guiding structure and 3D-printing material of CAD-CAM guides on the accuracy of guiding planes preparation. ...Guiding plane preparation of identical resin casts was performed using CAD-CAM guides …
BACKGROUND AND OBJECTIVE: To evaluate the effect of guiding structure and 3D-printing material of CAD-CAM guides on the accura …
The evolving role of EUS-guided tissue acquisition.
Ang TL, Wang LM. Ang TL, et al. J Dig Dis. 2021 Apr;22(4):204-213. doi: 10.1111/1751-2980.12976. Epub 2021 Mar 11. J Dig Dis. 2021. PMID: 33611846 Review.
The introduction of endoscopic ultrasound-guided fine-needle aspiration into clinical practice was a pivotal moment for diagnostic gastrointestinal endoscopy. ...Artificial intelligence may be especially important to guide clinical decision-making if biopsy results …
The introduction of endoscopic ultrasound-guided fine-needle aspiration into clinical practice was a pivotal moment for diagnostic ga …
34,015 results
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