Maternal cholestasis during pregnancy programs metabolic disease in offspring.
Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, Owen BM, Nikolova V, Ovadia C, Huang X, Vaarasmaki M, Baumann M, Jansen E, Albrecht C, Jarvelin MR, Marin JJ, Knisely AS, Williamson C.
Papacleovoulou G, et al.
J Clin Invest. 2013 Jul;123(7):3172-81. doi: 10.1172/JCI68927. Epub 2013 Jun 24.
J Clin Invest. 2013.
PMID: 23934127
Free PMC article.
Males had increased BMI, and females exhibited increased waist and hip girth compared with the offspring of uncomplicated pregnancies. We further investigated the effect of maternal cholestasis on the metabolism of adult offspring in the mouse. ...
Males had increased BMI, and females exhibited increased waist and hip girth compared with the offspring of uncomplicated pregnancies …