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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1992 1
2001 4
2002 3
2003 3
2005 4
2006 3
2007 3
2008 4
2009 3
2010 1
2011 6
2012 3
2013 2
2014 6
2015 9
2016 8
2017 2
2018 4
2019 8
2020 10
2021 18
2022 19
2023 19
2024 7

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139 results

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Page 1
Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries.
Harraz OF, Klug NR, Senatore AJ, Hill-Eubanks DC, Nelson MT. Harraz OF, et al. Circ Res. 2022 May 13;130(10):1531-1546. doi: 10.1161/CIRCRESAHA.122.320827. Epub 2022 Apr 6. Circ Res. 2022. PMID: 35382561 Free PMC article.
Activation of Piezo1 channels evoked currents that were sensitive to endothelial cell-specific Piezo1 deletion. Using genetically encoded Ca(2+) indicator mice and an ex vivo pressurized retina preparation, we found that activation of Piezo1 channels by mechanical forces t …
Activation of Piezo1 channels evoked currents that were sensitive to endothelial cell-specific Piezo1 deletion. Using genetically encoded Ca …
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer.
Ali LR, Garrido-Castro AC, Lenehan PJ, Bollenrucher N, Stump CT, Dougan M, Goel S, Shapiro GI, Tolaney SM, Dougan SK. Ali LR, et al. J Exp Med. 2023 Apr 3;220(4):e20220729. doi: 10.1084/jem.20220729. Epub 2023 Jan 23. J Exp Med. 2023. PMID: 36688919 Free PMC article.
Augmentation of the antitumor memory pool by ribociclib boosts the efficacy of subsequent PD-1 blockade in mouse models of melanoma and breast cancer, pointing toward sequential therapy as a potentially safe and synergistic strategy in patients....
Augmentation of the antitumor memory pool by ribociclib boosts the efficacy of subsequent PD-1 blockade in mouse models of melanoma a …
When the MOUSE leaves the house.
Blümich B, Anders J. Blümich B, et al. Magn Reson (Gott). 2021 Apr 16;2(1):149-160. doi: 10.5194/mr-2-149-2021. eCollection 2021. Magn Reson (Gott). 2021. PMID: 37904756 Free PMC article. Review.
Change is inherent to time being transient. With the NMR-MOUSE (MObile Universal Surface Explorer) having matured into an established NMR tool for nondestructive testing of materials, this forward-looking retrospective assesses the challenges the NMR-MOUSE faced whe …
Change is inherent to time being transient. With the NMR-MOUSE (MObile Universal Surface Explorer) having matured into an established …
T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity.
Finlay CM, Parkinson JE, Zhang L, Chan BHK, Ajendra J, Chenery A, Morrison A, Kaymak I, Houlder EL, Murtuza Baker S, Dickie BR, Boon L, Konkel JE, Hepworth MR, MacDonald AS, Randolph GJ, Rückerl D, Allen JE. Finlay CM, et al. Immunity. 2023 May 9;56(5):1064-1081.e10. doi: 10.1016/j.immuni.2023.02.016. Epub 2023 Mar 21. Immunity. 2023. PMID: 36948193 Free article.
The recent revolution in tissue-resident macrophage biology has resulted largely from murine studies performed in C57BL/6 mice. Here, using both C57BL/6 and BALB/c mice, we analyze immune cells in the pleural cavity. Unlike C57BL/6 mice, naive tissue-resident …
The recent revolution in tissue-resident macrophage biology has resulted largely from murine studies performed in C57BL/6 mice. Here, …
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Garcia-Diaz C, Pöysti A, Mereu E, Clements MP, Brooks LJ, Galvez-Cancino F, Castillo SP, Tang W, Beattie G, Courtot L, Ruiz S, Roncaroli F, Yuan Y, Marguerat S, Quezada SA, Heyn H, Parrinello S. Garcia-Diaz C, et al. Cell Rep. 2023 May 30;42(5):112472. doi: 10.1016/j.celrep.2023.112472. Epub 2023 May 5. Cell Rep. 2023. PMID: 37149862 Free article.
Glioblastoma (GBM) recurrence originates from invasive margin cells that escape surgical debulking, but to what extent these cells resemble their bulk counterparts remains unclear. Here, we generated three immunocompetent somatic GBM mouse models, driven by subtype-associa …
Glioblastoma (GBM) recurrence originates from invasive margin cells that escape surgical debulking, but to what extent these cells resemble …
Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors.
Demerlé C, Gorvel L, Mello M, Pastor S, Degos C, Zarubica A, Angelis F, Fiore F, Nunes JA, Malissen B, Greillier L, Guittard G, Luche H, Barlesi F, Olive D. Demerlé C, et al. J Immunother Cancer. 2023 May;11(5):e006348. doi: 10.1136/jitc-2022-006348. J Immunother Cancer. 2023. PMID: 37230538 Free PMC article.
In order to better understand HVEM18-10 effects in vivo and especially disentangle its CIS and TRANS effects, we developed a knockin (KI) mouse model expressing human BTLA (huBTLA(+/+)) and a KI mouse model expressing both huBTLA(+/+)/huHVEM(+/+) (double KI (DKI)). …
In order to better understand HVEM18-10 effects in vivo and especially disentangle its CIS and TRANS effects, we developed a knockin (KI) …
Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.
Bernard PL, Delconte R, Pastor S, Laletin V, Costa Da Silva C, Goubard A, Josselin E, Castellano R, Krug A, Vernerey J, Devillier R, Olive D, Verhoeyen E, Vivier E, Huntington ND, Nunes J, Guittard G. Bernard PL, et al. J Immunother Cancer. 2022 May;10(5):e004244. doi: 10.1136/jitc-2021-004244. J Immunother Cancer. 2022. PMID: 35589278 Free PMC article.
We then tested human NK cells functions. RESULTS: In Cish(fl/fl)Ncr1(Ki/+) mice, we detected no developmental or homeostatic difference in NK cells. ...Cish(fl/fl)Ncr1(Ki/+) NK cells display lower activation thresholds and Cish(fl/fl)Ncr1(Ki/+) mice are more resista …
We then tested human NK cells functions. RESULTS: In Cish(fl/fl)Ncr1(Ki/+) mice, we detected no developmental or homeostatic differen …
Linking epileptic phenotypes and neural extracellular matrix remodeling signatures in mouse models of epilepsy.
Blondiaux A, Jia S, Annamneedi A, Çalışkan G, Nebel J, Montenegro-Venegas C, Wykes RC, Fejtova A, Walker MC, Stork O, Gundelfinger ED, Dityatev A, Seidenbecher CI. Blondiaux A, et al. Neurobiol Dis. 2023 Nov;188:106324. doi: 10.1016/j.nbd.2023.106324. Epub 2023 Oct 12. Neurobiol Dis. 2023. PMID: 37838005 Free article.
The neural extracellular matrix (ECM) is dynamically modulated by physiological and pathophysiological activity and critically involved in controlling the brain's excitability. We used different epilepsy models, i.e. mice lacking the presynaptic scaffolding protein Bassoon …
The neural extracellular matrix (ECM) is dynamically modulated by physiological and pathophysiological activity and critically involved in c …
Zinc prevents vaginal candidiasis by inhibiting expression of an inflammatory fungal protein.
Roselletti E, Pericolini E, Nore A, Takacs P, Kozma B, Sala A, De Seta F, Comar M, Usher J, Brown GD, Wilson D. Roselletti E, et al. Sci Transl Med. 2023 Dec 6;15(725):eadi3363. doi: 10.1126/scitranslmed.adi3363. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055800
Here, we show that the PRA1 gene is strongly up-regulated during vaginal infections and that its expression positively correlated with proinflammatory cytokine concentrations in women. Genetic deletion of PRA1 prevented vaginal inflammation in mice, and application of a zi …
Here, we show that the PRA1 gene is strongly up-regulated during vaginal infections and that its expression positively correlated with proin …
Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors.
Patnaik A, Rosen LS, Tolaney SM, Tolcher AW, Goldman JW, Gandhi L, Papadopoulos KP, Beeram M, Rasco DW, Hilton JF, Nasir A, Beckmann RP, Schade AE, Fulford AD, Nguyen TS, Martinez R, Kulanthaivel P, Li LQ, Frenzel M, Cronier DM, Chan EM, Flaherty KT, Wen PY, Shapiro GI. Patnaik A, et al. Cancer Discov. 2016 Jul;6(7):740-53. doi: 10.1158/2159-8290.CD-16-0095. Epub 2016 May 23. Cancer Discov. 2016. PMID: 27217383
139 results