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39 results

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The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate.
Pan H, Yu H, Ravi V, Li C, Lee AP, Lian MM, Tay BH, Brenner S, Wang J, Yang H, Zhang G, Venkatesh B. Pan H, et al. Gigascience. 2016 Sep 9;5(1):36. doi: 10.1186/s13742-016-0144-3. Gigascience. 2016. PMID: 27609345 Free PMC article.
BACKGROUND: The ocean sunfish (Mola mola), which can grow up to a length of 2.7 m and weigh 2.3 tons, is the world's largest bony fish. ...A number of genes associated with the extracellular matrix, some of which are involved in the regulation of bone and car …
BACKGROUND: The ocean sunfish (Mola mola), which can grow up to a length of 2.7 m and weigh 2.3 tons, is the world's largest b …
Coevolution of the olfactory organ and its receptor repertoire in ray-finned fishes.
Policarpo M, Bemis KE, Laurenti P, Legendre L, Sandoz JC, Rétaux S, Casane D. Policarpo M, et al. BMC Biol. 2022 Sep 1;20(1):195. doi: 10.1186/s12915-022-01397-x. BMC Biol. 2022. PMID: 36050670 Free PMC article.
To explore this topic, we studied the evolutionary dynamics of the four main gene families (OR, TAAR, ORA/VR1 and OlfC/VR2) coding for olfactory receptors in 185 species of ray-finned fishes. RESULTS: The large variation in the number of functional genes, between 28 in the …
To explore this topic, we studied the evolutionary dynamics of the four main gene families (OR, TAAR, ORA/VR1 and OlfC/VR2) coding for olfac …
Identifying transcript-level differential expression in primary human immune cells.
Mola S, Beauchamp C, Boucher G, Lesage S, Karaky M, Goyette P, Foisy S, Rioux JD. Mola S, et al. Mol Immunol. 2023 Jan;153:181-193. doi: 10.1016/j.molimm.2022.12.005. Epub 2022 Dec 15. Mol Immunol. 2023. PMID: 36527757
Next, we developed a heuristic approach to identify genes where two or more transcripts have distinct expression patterns across lymphoid and/or myeloid populations. ...CONCLUSIONS: This analytic approach successfully identified multi-transcript genes that are diffe …
Next, we developed a heuristic approach to identify genes where two or more transcripts have distinct expression patterns across lymp …
In silico prediction of the enzymes involved in the degradation of the herbicide molinate by Gulosibacter molinativorax ON4T.
Lopes AR, Bunin E, Viana AT, Froufe H, Muñoz-Merida A, Pinho D, Figueiredo J, Barroso C, Vaz-Moreira I, Bellanger X, Egas C, Nunes OC. Lopes AR, et al. Sci Rep. 2022 Sep 15;12(1):15502. doi: 10.1038/s41598-022-18732-5. Sci Rep. 2022. PMID: 36109598 Free PMC article.
Gulosibacter molinativorax ON4(T) is the only known organism to produce molinate hydrolase (MolA), which catalyses the breakdown of the thiocarbamate herbicide into azepane-1-carboxylic acid (ACA) and ethanethiol. A combined genomic and transcriptomic strategy was used to …
Gulosibacter molinativorax ON4(T) is the only known organism to produce molinate hydrolase (MolA), which catalyses the breakdown of t …
Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases.
Karaky M, Boucher G, Mola S, Foisy S, Beauchamp C, Rivard ME, Burnette M, Gosselin H; iGenoMed Consortium; Bitton A, Charron G, Goyette P, Rioux JD. Karaky M, et al. PLoS Genet. 2022 Sep 26;18(9):e1010189. doi: 10.1371/journal.pgen.1010189. eCollection 2022 Sep. PLoS Genet. 2022. PMID: 36155972 Free PMC article.
Given the importance of myeloid cells in IBD pathogenesis, the current study aimed to uncover the role of genes within IBD genetic loci that are endogenously expressed in this cell lineage. ...CONCLUSION: Our results support a causal role for the PTGIR, PTGER4, ZBTB40, SLC …
Given the importance of myeloid cells in IBD pathogenesis, the current study aimed to uncover the role of genes within IBD genetic lo …
Prevalence of multi-drug resistant bacteria associated with foods and drinks in Nigeria (2015-2020): A systematic review.
Mola I, Onibokun A, Oranusi S. Mola I, et al. Ital J Food Saf. 2021 Nov 22;10(4):9417. doi: 10.4081/ijfs.2021.9417. eCollection 2021 Nov 22. Ital J Food Saf. 2021. PMID: 35018289 Free PMC article.
When ARB-contaminated foods are consumed, the spread of antibiotic resistant genes may affect the gut microbiome thereby contributing to the pool of antibiotic-resistance genes (ARG) in the human gut (Gekemidis et al, 2018). MDR bacteria have been defined as …
When ARB-contaminated foods are consumed, the spread of antibiotic resistant genes may affect the gut microbiome thereby contributing …
Evolutionary Dynamics of the OR Gene Repertoire in Teleost Fishes: Evidence of an Association with Changes in Olfactory Epithelium Shape.
Policarpo M, Bemis KE, Tyler JC, Metcalfe CJ, Laurenti P, Sandoz JC, Rétaux S, Casane D. Policarpo M, et al. Mol Biol Evol. 2021 Aug 23;38(9):3742-3753. doi: 10.1093/molbev/msab145. Mol Biol Evol. 2021. PMID: 33950257 Free PMC article.
We found a large range of variation in the number of functional OR genes, from 15 in the Broad-nose Pipefish Syngnathus typhle and the Ocean Sunfish Mola mola, to 429 in the Zig-zag Eel Mastacembelus armatus. The number of OR genes was higher in specie …
We found a large range of variation in the number of functional OR genes, from 15 in the Broad-nose Pipefish Syngnathus typhle and th …
Comparative ontogenetic and transcriptomic analyses shed light on color pattern divergence in cichlid fishes.
Kratochwil CF, Liang Y, Gerwin J, Franchini P, Meyer A. Kratochwil CF, et al. Evol Dev. 2022 Sep;24(5):158-170. doi: 10.1111/ede.12416. Epub 2022 Aug 15. Evol Dev. 2022. PMID: 35971657
We therefore also provide evidence that agrp2 is associated with the loss of the nonstereotypic oblique stripe of Mylochromis mola. Complementary ontogenetic data give insights into the development of stripe patterns as well as vertical bar patterns that both develop poste …
We therefore also provide evidence that agrp2 is associated with the loss of the nonstereotypic oblique stripe of Mylochromis mola. C …
A transcriptome-based approach to identify functional modules within and across primary human immune cells.
Mola S, Foisy S, Boucher G, Major F, Beauchamp C, Karaky M, Goyette P, Lesage S, Rioux JD. Mola S, et al. PLoS One. 2020 May 29;15(5):e0233543. doi: 10.1371/journal.pone.0233543. eCollection 2020. PLoS One. 2020. PMID: 32469933 Free PMC article.
Many studies have taken advantage of the correlation in the expression patterns of the transcriptome to infer a potential biologic function of uncharacterized genes, and multiple groups have examined the relationship between co-expression, co-regulation, and gene function …
Many studies have taken advantage of the correlation in the expression patterns of the transcriptome to infer a potential biologic function …
Substance P and neprilysin in chronic pancreatitis.
Mascetta G, di Mola FF, Tavano F, Selvaggi F, Giese N, Bassi C, Büchler MW, Friess H, di Sebastiano P. Mascetta G, et al. Eur Surg Res. 2012;48(3):131-8. doi: 10.1159/000337869. Epub 2012 May 8. Eur Surg Res. 2012. PMID: 22572771
39 results