Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases.
Karaky M, Boucher G, Mola S, Foisy S, Beauchamp C, Rivard ME, Burnette M, Gosselin H; iGenoMed Consortium; Bitton A, Charron G, Goyette P, Rioux JD.
Karaky M, et al.
PLoS Genet. 2022 Sep 26;18(9):e1010189. doi: 10.1371/journal.pgen.1010189. eCollection 2022 Sep.
PLoS Genet. 2022.
PMID: 36155972
Free PMC article.
Given the importance of myeloid cells in IBD pathogenesis, the current study aimed to uncover the role of genes within IBD genetic loci that are endogenously expressed in this cell lineage. ...CONCLUSION: Our results support a causal role for the PTGIR, PTGER4, ZBTB40, SLC …
Given the importance of myeloid cells in IBD pathogenesis, the current study aimed to uncover the role of genes within IBD genetic lo …