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Geodesic density regression for correcting 4DCT pulmonary respiratory motion artifacts.
Shao W, Pan Y, Durumeric OC, Reinhardt JM, Bayouth JE, Rusu M, Christensen GE. Shao W, et al. Med Image Anal. 2021 Aug;72:102140. doi: 10.1016/j.media.2021.102140. Epub 2021 Jun 21. Med Image Anal. 2021. PMID: 34214957 Free PMC article.
The simulation shows that the GDR algorithm has achieved significantly more accurate Jacobian images and sharper template images, and is less sensitive to data dropout than the GIR algorithm. ...
The simulation shows that the GDR algorithm has achieved significantly more accurate Jacobian images and sharper template images, and …
Radiation-induced airway changes and downstream ventilation decline in a swine model.
Wallat EM, Wuschner AE, Flakus MJ, Christensen GE, Reinhardt JM, Shanmuganayagam D, Bayouth JE. Wallat EM, et al. Biomed Phys Eng Express. 2021 Oct 29;7(6):10.1088/2057-1976/ac3197. doi: 10.1088/2057-1976/ac3197. Biomed Phys Eng Express. 2021. PMID: 34670195 Free PMC article.
Changes in luminal area (Ai) and square root of wall area (WA) for each airway were investigated. Changes in ventilation were assessed using the Jacobian ratio and were measured in three different regions: the inferior left lung <5 Gy (ILL), the superior left lung <5 …
Changes in luminal area (Ai) and square root of wall area (WA) for each airway were investigated. Changes in ventilation were assessed using …
Robust quantification of CT-ventilation biomarker techniques and repeatability in a porcine model.
Flakus MJ, Wuschner AE, Wallat EM, Shao W, Meudt J, Shanmuganayagam D, Christensen GE, Reinhardt JM, Bayouth JE. Flakus MJ, et al. Med Phys. 2023 Oct;50(10):6366-6378. doi: 10.1002/mp.16400. Epub 2023 Apr 7. Med Phys. 2023. PMID: 36999913
As surrogates for ventilation, multiple local expansion ratios (LERs) were calculated from the acquired CT scans using Jacobian-based post-processing techniques. LER2 measured local expansion between an image pair using either inhale and exhale BH-CT images or two 4DCT bre …
As surrogates for ventilation, multiple local expansion ratios (LERs) were calculated from the acquired CT scans using Jacobian-based …
Normalization of brain morphology after surgery in sagittal craniosynostosis.
Brooks ED, Yang J, Beckett JS, Lacadie C, Scheinost D, Persing S, Zellner EG, Oosting D, Keifer C, Friedman HE, Wyk BV, Jou RJ, Sun H, Gary C, Duncan CC, Constable RT, Pelphrey KA, Persing JA. Brooks ED, et al. J Neurosurg Pediatr. 2016 Apr;17(4):460-8. doi: 10.3171/2015.7.PEDS15221. Epub 2015 Dec 18. J Neurosurg Pediatr. 2016. PMID: 26684766 Free PMC article.
The authors used one such technique, deformation-based morphometry (DBM) Jacobian mapping, to determine how previously treated adolescents with sagittal NSC (sNSC) significantly differ in brain anatomy compared with healthy matched controls up to 11.5 years after surgery. …
The authors used one such technique, deformation-based morphometry (DBM) Jacobian mapping, to determine how previously treated adoles …
Radiation-induced Hounsfield unit change correlates with dynamic CT perfusion better than 4DCT-based ventilation measures in a novel-swine model.
Wuschner AE, Wallat EM, Flakus MJ, Shanmuganayagam D, Meudt J, Christensen GE, Reinhardt JM, Miller JR, Lawless MJ, Baschnagel AM, Bayouth JE. Wuschner AE, et al. Sci Rep. 2021 Jun 23;11(1):13156. doi: 10.1038/s41598-021-92609-x. Sci Rep. 2021. PMID: 34162987 Free PMC article.
Imaging (a contrast enhanced dynamic perfusion CT in the swine and 4DCT in the humans) was performed prior to and post-RT. Jacobian elasticity maps were calculated on all 4DCT images. Contours were created from the isodose lines to discretize analysis into 10 Gy dose bins. …
Imaging (a contrast enhanced dynamic perfusion CT in the swine and 4DCT in the humans) was performed prior to and post-RT. Jacobian e …
Volumetric transformation of brain anatomy.
Christensen GE, Joshi SC, Miller MI. Christensen GE, et al. IEEE Trans Med Imaging. 1997 Dec;16(6):864-77. doi: 10.1109/42.650882. IEEE Trans Med Imaging. 1997. PMID: 9533586
The high-dimensional large deformations are vector fields generated via the mismatch between the template and target-image volumes constrained to be the solution of a Navier-Stokes fluid model. As part of this procedure, the Jacobian of the transformation is tracked, insur …
The high-dimensional large deformations are vector fields generated via the mismatch between the template and target-image volumes constrain …
Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry.
Christensen GE, Song JH, Lu W, El Naqa I, Low DA. Christensen GE, et al. Med Phys. 2007 Jun;34(6):2155-63. doi: 10.1118/1.2731029. Med Phys. 2007. PMID: 17654918
The pointwise expansion and compression of lung tissue was measured by computing the Jacobian of the transformations used to register the images. The logarithm of the Jacobian was computed so that expansion and compression of the lung were scaled equally. ...In four …
The pointwise expansion and compression of lung tissue was measured by computing the Jacobian of the transformations used to register …