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Equine Arteritis Virus Uses Equine CXCL16 as an Entry Receptor.
Sarkar S, Chelvarajan L, Go YY, Cook F, Artiushin S, Mondal S, Anderson K, Eberth J, Timoney PJ, Kalbfleisch TS, Bailey E, Balasuriya UB. Sarkar S, et al. J Virol. 2016 Jan 13;90(7):3366-84. doi: 10.1128/JVI.02455-15. J Virol. 2016. PMID: 26764004 Free PMC article.
The collective data from this study provide confirmatory evidence that the transmembrane form of EqCXCL16 likely plays a major role in EAV host cell entry processes, possibly acting as a primary receptor molecule for this virus. IMPORTANCE: Outbreaks of EVA can be a source …
The collective data from this study provide confirmatory evidence that the transmembrane form of EqCXCL16 likely plays a major role in EAV h …
Intrahost Selection Pressure Drives Equine Arteritis Virus Evolution during Persistent Infection in the Stallion Reproductive Tract.
Nam B, Mekuria Z, Carossino M, Li G, Zheng Y, Zhang J, Cook RF, Shuck KM, Campos JR, Squires EL, Troedsson MHT, Timoney PJ, Balasuriya UBR. Nam B, et al. J Virol. 2019 May 29;93(12):e00045-19. doi: 10.1128/JVI.00045-19. Print 2019 Jun 15. J Virol. 2019. PMID: 30918077 Free PMC article.
Equine arteritis virus (EAV) is the causative agent of equine viral arteritis (EVA), a reproductive and respiratory disease of horses. Following natural infection, 10 to 70% of infected stallions can become carriers of EAV and continue to shed virus in the semen. ...
Equine arteritis virus (EAV) is the causative agent of equine viral arteritis (EVA), a reproductive and respiratory disease of horses …
Downregulation of MicroRNA eca-mir-128 in Seminal Exosomes and Enhanced Expression of CXCL16 in the Stallion Reproductive Tract Are Associated with Long-Term Persistence of Equine Arteritis Virus.
Carossino M, Dini P, Kalbfleisch TS, Loynachan AT, Canisso IF, Shuck KM, Timoney PJ, Cook RF, Balasuriya UBR. Carossino M, et al. J Virol. 2018 Apr 13;92(9):e00015-18. doi: 10.1128/JVI.00015-18. Print 2018 May 1. J Virol. 2018. PMID: 29444949 Free PMC article.
Semen quality of stallions challenged with the Kentucky 84 strain of equine arteritis virus.
Campos JR, Breheny P, Araujo RR, Troedsson MH, Squires EL, Timoney PJ, Balasuriya UB. Campos JR, et al. Theriogenology. 2014 Nov;82(8):1068-79. doi: 10.1016/j.theriogenology.2014.07.004. Epub 2014 Jul 24. Theriogenology. 2014. PMID: 25156969
Equine arteritis virus (EAV) is the causal agent of equine viral arteritis (EVA), a respiratory and reproductive disease of equids. Some strains of EAV can cause fever, leukopenia, and dependent edema of the limbs, scrotum, and preputium in the acutely infected stallion. . …
Equine arteritis virus (EAV) is the causal agent of equine viral arteritis (EVA), a respiratory and reproductive disease of equids. S …
Infection of embryos following insemination of donor mares with equine arteritis virus infective semen.
Broaddus CC, Balasuriya UB, Timoney PJ, White JL, Makloski C, Torrisi K, Payton M, Holyoak GR. Broaddus CC, et al. Theriogenology. 2011 Jul 1;76(1):47-60. doi: 10.1016/j.theriogenology.2011.01.017. Epub 2011 Feb 22. Theriogenology. 2011. PMID: 21345485
Of the 26 donor mares, 15 were unvaccinated and seronegative for antibodies to EAV and 11 were vaccinated for the first time with a commercially available modified live virus vaccine against EVA before breeding and subsequent embryo transfer. All donor mares were bred with …
Of the 26 donor mares, 15 were unvaccinated and seronegative for antibodies to EAV and 11 were vaccinated for the first time with a commerci …
Equine Arteritis Virus Elicits a Mucosal Antibody Response in the Reproductive Tract of Persistently Infected Stallions.
Carossino M, Wagner B, Loynachan AT, Cook RF, Canisso IF, Chelvarajan L, Edwards CL, Nam B, Timoney JF, Timoney PJ, Balasuriya UBR. Carossino M, et al. Clin Vaccine Immunol. 2017 Oct 5;24(10):e00215-17. doi: 10.1128/CVI.00215-17. Print 2017 Oct. Clin Vaccine Immunol. 2017. PMID: 28814389 Free PMC article.
Interestingly, seminal plasma IgG1 and IgG4/7 possessed virus-neutralizing activity, while seminal plasma IgA and IgG3/5 did not. However, virus-neutralizing IgG1 and IgG4/7 in seminal plasma were not effective in preventing viral infectivity. ...
Interestingly, seminal plasma IgG1 and IgG4/7 possessed virus-neutralizing activity, while seminal plasma IgA and IgG3/5 did not. How …
Equine viral arteritis: current status and prevention.
Holyoak GR, Balasuriya UB, Broaddus CC, Timoney PJ. Holyoak GR, et al. Theriogenology. 2008 Aug;70(3):403-14. doi: 10.1016/j.theriogenology.2008.04.020. Epub 2008 May 27. Theriogenology. 2008. PMID: 18502495
Recently, there has been increased interest in equine viral arteritis (EVA) among veterinarians and horse owners. Outbreaks of the disease were identified initially in New Mexico, USA in 2006, and in the Normandy region of France in the summer of 2007. ...In light of the i …
Recently, there has been increased interest in equine viral arteritis (EVA) among veterinarians and horse owners. Outbreaks of the di …
Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8+ T and CD21+ B Lymphocytes but Not for Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract.
Carossino M, Loynachan AT, Canisso IF, Cook RF, Campos JR, Nam B, Go YY, Squires EL, Troedsson MHT, Swerczek T, Del Piero F, Bailey E, Timoney PJ, Balasuriya UBR. Carossino M, et al. J Virol. 2017 Jun 9;91(13):e00418-17. doi: 10.1128/JVI.00418-17. Print 2017 Jul 1. J Virol. 2017. PMID: 28424285 Free PMC article.
Equine arteritis virus (EAV) has a global impact on the equine industry as the causative agent of equine viral arteritis (EVA), a respiratory, systemic, and reproductive disease of equids. ...
Equine arteritis virus (EAV) has a global impact on the equine industry as the causative agent of equine viral arteritis (EVA), a res …
Development and characterization of an infectious cDNA clone of the modified live virus vaccine strain of equine arteritis virus.
Zhang J, Go YY, Huang CM, Meade BJ, Lu Z, Snijder EJ, Timoney PJ, Balasuriya UB. Zhang J, et al. Clin Vaccine Immunol. 2012 Aug;19(8):1312-21. doi: 10.1128/CVI.00302-12. Epub 2012 Jun 27. Clin Vaccine Immunol. 2012. PMID: 22739697 Free PMC article.
When challenged with the heterologous EAV KY84 strain, the rMLVB vaccine virus protected immunized horses in regard to reducing the magnitude and duration of viremia and virus shedding but did not suppress the development of signs of EVA, although these were reduced in cli …
When challenged with the heterologous EAV KY84 strain, the rMLVB vaccine virus protected immunized horses in regard to reducing the magnitud …
18 results