Identification of a novel HLA-DRB1*12 allele (DRB1*1210) in the Korean population

Tissue Antigens. 2004 Oct;64(4):518-9. doi: 10.1111/j.1399-0039.2004.00309.x.

Abstract

At least 11 HLA-DRB1*12 alleles have been identified to date. We report a new HLA-DRB1*12 allele, DRB1*1210, that was identified in the Korean population. This new allele differs from HLA-DRB1*120101 by a single nucleotide at position 40 (G-->A) in exon 1 that falls within codon--16 (GTT-->ATT). This change results in a single valine to isoleucine amino acid alteration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Substitution / genetics*
  • Base Sequence
  • Exons / genetics*
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Humans
  • Korea
  • Molecular Sequence Data

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains