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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1956 1
1957 1
1959 2
1964 2
1965 5
1966 5
1967 13
1968 11
1969 33
1970 34
1971 35
1972 62
1973 33
1974 36
1975 68
1976 72
1977 72
1978 51
1979 56
1980 66
1981 96
1982 98
1983 117
1984 144
1985 159
1986 198
1987 222
1988 222
1989 249
1990 310
1991 312
1992 346
1993 391
1994 435
1995 483
1996 508
1997 513
1998 547
1999 599
2000 719
2001 764
2002 754
2003 871
2004 900
2005 1026
2006 1087
2007 1124
2008 1186
2009 1132
2010 1177
2011 1223
2012 1263
2013 1343
2014 1242
2015 1267
2016 1114
2017 1168
2018 1176
2019 1173
2020 1269
2021 1196
2022 1075
2023 1031
2024 399

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30,231 results

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Page 1
Structure-Activity Relationship Assessment of Sophorolipid Ester Derivatives against Model Bacteria Strains.
Totsingan F, Liu F, Gross RA. Totsingan F, et al. Molecules. 2021 May 19;26(10):3021. doi: 10.3390/molecules26103021. Molecules. 2021. PMID: 34069408 Free PMC article.
Modified SLs were identified with promising antimicrobial activities against Gram-positive human pathogens with moderate selectivity (therapeutic index, TI = EC(50)/MIC(B. cereus) = 6-33). SL-butyl ester exhibited the best antimicrobial activity (MIC = 12 muM) and selectiv …
Modified SLs were identified with promising antimicrobial activities against Gram-positive human pathogens with moderate selectivity (therap …
Ester-Linked Crystalline Covalent Organic Frameworks.
Zhao C, Lyu H, Ji Z, Zhu C, Yaghi OM. Zhao C, et al. J Am Chem Soc. 2020 Aug 26;142(34):14450-14454. doi: 10.1021/jacs.0c07015. Epub 2020 Aug 14. J Am Chem Soc. 2020. PMID: 32786782
Ester-linked, crystalline, porous covalent organic frameworks (COFs) have been synthesized and structurally characterized. ...This work expands the scope of reticular chemistry to include, for the first time, crystalline ester-linked COFs related to common polyester …
Ester-linked, crystalline, porous covalent organic frameworks (COFs) have been synthesized and structurally characterized. ...This wo …
A comprehensive two-scale model for predicting the oxidizability of fatty acid methyl ester mixtures.
Touffet M, Smith P, Vitrac O. Touffet M, et al. Food Res Int. 2023 Nov;173(Pt 1):113289. doi: 10.1016/j.foodres.2023.113289. Epub 2023 Jul 18. Food Res Int. 2023. PMID: 37803602
We rigorously tested and validated the proposed two-scale scheme on binary and ternary mixtures of fatty acid methyl esters (FAMEs), yielding three key insights: (1) The abstraction of labile protons hinges on the carrier, defying the conventional focus on hydroperoxyl rad …
We rigorously tested and validated the proposed two-scale scheme on binary and ternary mixtures of fatty acid methyl esters (FAMEs), …
[Evaluation of the Oral Absorption of Ester-type Prodrugs].
Ohura K. Ohura K. Yakugaku Zasshi. 2020;140(3):369-376. doi: 10.1248/yakushi.19-00225. Yakugaku Zasshi. 2020. PMID: 32115554 Free article. Review. Japanese.
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respective predominant carboxylesterase (CES) isozymes. In order to provide high blood concentrations of the parent drugs, it is preferable that prod …
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respectiv …
Evaluation of Oxidation Parameters of Caffeic Acid Phenethyl Ester Comparing with Caffeic Acid, Ascorbyl Palmitate, and alpha-Tocopherol on the Thermal Oxidation Model.
Shin JA, Kim YM, Duan B, Lee KT. Shin JA, et al. J Oleo Sci. 2020;69(2):93-103. doi: 10.5650/jos.ess19152. J Oleo Sci. 2020. PMID: 32023581 Free article.
In this study, the antioxidative capacity of caffeic acid (CA), ascorbyl palmitate (AP), alpha-tocopherol (alpha-TO), and caffeic acid phenethyl ester (CAPE) was evaluated under the thermal oxidation model, in which 200 ppm of each compound was added to soybean oil, …
In this study, the antioxidative capacity of caffeic acid (CA), ascorbyl palmitate (AP), alpha-tocopherol (alpha-TO), and caffeic acid phene …
Phenethyl ester of rosmarinic acid ameliorates experimental autoimmune encephalomyelitis.
Stegnjaić G, Lazarević M, Diamantis DA, Djedović N, Jevtić B, Stanisavljević S, Dimitrijević M, Momčilović M, Tzakos AG, Miljković Đ. Stegnjaić G, et al. Immunol Lett. 2022 Dec;251-252:9-19. doi: 10.1016/j.imlet.2022.09.006. Epub 2022 Sep 29. Immunol Lett. 2022. PMID: 36183900
The aim of the study was to evaluate the immunomodulatory properties of a recently developed phenethyl ester derivative of rosmarinic acid (PERA), with enhanced ability of diffusion through biological membranes, in an animal model of the central nervous system (CNS) …
The aim of the study was to evaluate the immunomodulatory properties of a recently developed phenethyl ester derivative of rosmarinic …
2,4-Diketo esters: Crucial intermediates for drug discovery.
Joksimović N, Janković N, Davidović G, Bugarčić Z. Joksimović N, et al. Bioorg Chem. 2020 Dec;105:104343. doi: 10.1016/j.bioorg.2020.104343. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33086180 Review.
Also, many 2,4-diketo ester derivatives have been prepared due to their suitable synthesis. ...Herein, numerous aspects of 2,4-diketo esters will be summarized, including synthesis and isolation of their derivatives, development of novel synthetic methodologies, the …
Also, many 2,4-diketo ester derivatives have been prepared due to their suitable synthesis. ...Herein, numerous aspects of 2,4-diketo …
Homarine Alkyl Ester Derivatives as Promising Acetylcholinesterase Inhibitors.
João KG, Videira RA, Paiva-Martins F, Valentão P, Pereira DM, Andrade PB. João KG, et al. ChemMedChem. 2021 Nov 5;16(21):3315-3325. doi: 10.1002/cmdc.202100265. Epub 2021 Aug 26. ChemMedChem. 2021. PMID: 34342141
Results showed that all homarine alkyl esters are able to inhibit AChE by a competitive inhibition mode. The effectiveness of AChE inhibition increases with the alkyl side chain length of the homarine esters, being HO-C(16) (IC(50) =7.573.32 muM and K(i) =18.962.28 …
Results showed that all homarine alkyl esters are able to inhibit AChE by a competitive inhibition mode. The effectiveness of AChE in …
Notch Signaling Mediates Radiation-Induced Smooth Muscle Cell Hypermuscularization and Cerebral Vasculopathy.
Yang Y, Li H, Xu Y, Xie J, Liu Q, Shi Z, Huang J, Cheng J, Chen S, Chen S, Zhao X, Li S, Zhang Z, Cai J, He B, Lin WJ, Shen Q, Li Y, Tang Y. Yang Y, et al. Stroke. 2022 Dec;53(12):3751-3762. doi: 10.1161/STROKEAHA.122.040697. Epub 2022 Oct 28. Stroke. 2022. PMID: 36305312
The effect of N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester, a Notch inhibitor, was used to investigate the vascular pathogenesis of RIBI mouse model. ...Importantly, Notch inhibition by N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycin …
The effect of N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester, a Notch inhibitor, was used to investigate the v …
30,231 results
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