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Year Number of Results
2003 1
2008 1
2009 1
2011 1
2013 1
2014 2
2015 2
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2020 2
2021 1
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2023 4
2024 0

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16 results

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Page 1
Morpholino-driven gene editing: A new horizon for disease treatment and prevention.
Subbotina E, Koganti SR, Hodgson-Zingman DM, Zingman LV. Subbotina E, et al. Clin Pharmacol Ther. 2016 Jan;99(1):21-5. doi: 10.1002/cpt.276. Epub 2015 Nov 10. Clin Pharmacol Ther. 2016. PMID: 26474085 Free PMC article. Review.
Here we discuss the uniquely powerful and adaptable approach of morpholino-driven modification of normal and mutant gene expression as a pathway to health....
Here we discuss the uniquely powerful and adaptable approach of morpholino-driven modification of normal and mutant gene expression a …
OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Shapiro JA, Gaonkar KS, Spielman SJ, Savonen CL, Bethell CJ, Jin R, Rathi KS, Zhu Y, Egolf LE, Farrow BK, Miller DP, Yang Y, Koganti T, Noureen N, Koptyra MP, Duong N, Santi M, Kim J, Robins S, Storm PB, Mack SC, Lilly JV, Xie HM, Jain P, Raman P, Rood BR, Lulla RR, Nazarian J, Kraya AA, Vaksman Z, Heath AP, Kline C, Scolaro L, Viaene AN, Huang X, Way GP, Foltz SM, Zhang B, Poetsch AR, Mueller S, Ennis BM, Prados M, Diskin SJ, Zheng S, Guo Y, Kannan S, Waanders AJ, Margol AS, Kim MC, Hanson D, Van Kuren N, Wong J, Kaufman RS, Coleman N, Blackden C, Cole KA, Mason JL, Madsen PJ, Koschmann CJ, Stewart DR, Wafula E, Brown MA, Resnick AC, Greene CS, Rokita JL, Taroni JN; Children’s Brain Tumor Network; Pacific Pediatric Neuro-Oncology Consortium. Shapiro JA, et al. Cell Genom. 2023 May 31;3(7):100340. doi: 10.1016/j.xgen.2023.100340. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492101 Free PMC article.
Feasibility, Sustainability, and Effectiveness of the Implementation of "Facility-Team-Driven" Approach for Improving the Quality of Newborn Care in South India.
Venugopal S, Patil RB, Thukral A, Koganti RA, Kumar Dl V, Sankar MJ, Agarwal R, Verma A, Deorari AK; Team Shimoga Medical College. Venugopal S, et al. Indian J Pediatr. 2023 Oct;90(10):974-981. doi: 10.1007/s12098-023-04518-8. Epub 2023 Jun 3. Indian J Pediatr. 2023. PMID: 37269503
CONCLUSIONS: The present study demonstrates the feasibility, sustainability, and effectiveness of a facility-team-driven QI approach augmented with capacity building and post-training supportive supervision....
CONCLUSIONS: The present study demonstrates the feasibility, sustainability, and effectiveness of a facility-team-driven QI approach …
Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells.
Singh A, Dashnyam M, Chim B, Escobar TM, Dulcey AE, Hu X, Wilson KM, Koganti PP, Spinner CA, Xu X, Jadhav A, Southall N, Marugan J, Selvaraj V, Lazarevic V, Muljo SA, Ferrer M. Singh A, et al. Sci Rep. 2020 Feb 28;10(1):3766. doi: 10.1038/s41598-020-60610-5. Sci Rep. 2020. PMID: 32111885 Free PMC article.
Here, we report that anxiolytic FGIN-1-27 inhibits differentiation and pathogenicity of Th17 cells in vitro and in vivo using the experimental autoimmune encephalomyelitis (EAE) model of Th17 cell-driven pathology. Remarkably, we found that the effects of FGIN-1-27 were in …
Here, we report that anxiolytic FGIN-1-27 inhibits differentiation and pathogenicity of Th17 cells in vitro and in vivo using the experiment …
B lymphocytes from patients with a hypomorphic mutation in STAT3 resist Epstein-Barr virus-driven cell proliferation.
Koganti S, de la Paz A, Freeman AF, Bhaduri-McIntosh S. Koganti S, et al. J Virol. 2014 Jan;88(1):516-24. doi: 10.1128/JVI.02601-13. Epub 2013 Oct 30. J Virol. 2014. PMID: 24173212 Free PMC article.
In efforts to delineate the contribution of signal transducer and activator of transcription 3 (STAT3) toward EBV-driven cell proliferation, we have discovered that B cells from patients with autosomal dominant hyper-IgE syndrome (AD-HIES) resist such EBV oncogene-drive …
In efforts to delineate the contribution of signal transducer and activator of transcription 3 (STAT3) toward EBV-driven cell prolife …
Treatment Strategies and Outcomes of Emergency Left Main Percutaneous Coronary Intervention.
Bajaj R, Ramasamy A, Brown JT, Koganti S, Little C, Rathod KS, Jones DA, Rees P, Guttmann O, Lockie T, Ozkor M, Mathur A, Kalra SS, Baumbach A, Bourantas CV, Rakhit R, O'Mahony C. Bajaj R, et al. Am J Cardiol. 2022 Aug 15;177:1-6. doi: 10.1016/j.amjcard.2022.04.043. Epub 2022 Jun 19. Am J Cardiol. 2022. PMID: 35732552
Provisional stenting appears to be the preferred option with the successful restoration of coronary flow in most cases despite complex anatomy. High 30-day mortality is driven by the presence of cardiogenic shock, OOHCA, and failure to restore or improve coronary flow....
Provisional stenting appears to be the preferred option with the successful restoration of coronary flow in most cases despite complex anato …
STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes.
McIntosh MT, Koganti S, Boatwright JL, Li X, Spadaro SV, Brantly AC, Ayers JB, Perez RD, Burton EM, Burgula S, MacCarthy T, Bhaduri-McIntosh S. McIntosh MT, et al. PLoS Pathog. 2020 Oct 1;16(10):e1008849. doi: 10.1371/journal.ppat.1008849. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33002095 Free PMC article.
We had previously found that EBV, through activation of cellular STAT3 prevents phosphorylation of Chk1, and thereby, suppresses activation of the intra-S phase cell-cycle checkpoint, a potent barrier to oncogene-driven proliferation. This observation prompted us to examin …
We had previously found that EBV, through activation of cellular STAT3 prevents phosphorylation of Chk1, and thereby, suppresses activation …
STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation.
Koganti S, Hui-Yuen J, McAllister S, Gardner B, Grasser F, Palendira U, Tangye SG, Freeman AF, Bhaduri-McIntosh S. Koganti S, et al. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4946-51. doi: 10.1073/pnas.1400683111. Epub 2014 Mar 17. Proc Natl Acad Sci U S A. 2014. PMID: 24639502 Free PMC article.
Using Epstein-Barr virus (EBV) as a source of oncogenes, we have previously shown that EBV-driven cell proliferation requires the cellular transcription factor STAT3. EBV infection is rapidly followed by activation and increased expression of STAT3, which mediates relaxati …
Using Epstein-Barr virus (EBV) as a source of oncogenes, we have previously shown that EBV-driven cell proliferation requires the cel …
Musclin is an activity-stimulated myokine that enhances physical endurance.
Subbotina E, Sierra A, Zhu Z, Gao Z, Koganti SR, Reyes S, Stepniak E, Walsh SA, Acevedo MR, Perez-Terzic CM, Hodgson-Zingman DM, Zingman LV. Subbotina E, et al. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):16042-7. doi: 10.1073/pnas.1514250112. Epub 2015 Dec 14. Proc Natl Acad Sci U S A. 2015. PMID: 26668395 Free PMC article.
We use human primary myoblast culture and in vivo murine models to establish that the activity-related production of musclin is driven by Ca(2+)-dependent activation of Akt1 and the release of musclin-encoding gene (Ostn) transcription from forkhead box O1 transcription fa …
We use human primary myoblast culture and in vivo murine models to establish that the activity-related production of musclin is driven …
16 results