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Showing results for defend, li
Search for defeng, li instead (2 results)
Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors.
Dai Z, Liu WC, Chen XY, Wang X, Li JL, Zhang X. Dai Z, et al. Front Immunol. 2023 May 18;14:1178662. doi: 10.3389/fimmu.2023.1178662. eCollection 2023. Front Immunol. 2023. PMID: 37275856 Free PMC article. Review.
Gasdermin D (GSDMD)-mediated pyroptosis and downstream inflammation are important self-protection mechanisms against stimuli and infections. Hosts can defend against intracellular bacterial infections by inducing cell pyroptosis, which triggers the clearance of pathogens. …
Gasdermin D (GSDMD)-mediated pyroptosis and downstream inflammation are important self-protection mechanisms against stimuli and infections. …
Anxa1 in smooth muscle cells protects against acute aortic dissection.
Zhou C, Lin Z, Cao H, Chen Y, Li J, Zhuang X, Ma D, Ji L, Li W, Xu S, Pan B, Zheng L. Zhou C, et al. Cardiovasc Res. 2022 May 6;118(6):1564-1582. doi: 10.1093/cvr/cvab109. Cardiovasc Res. 2022. PMID: 33757117
CONCLUSIONS: Our findings demonstrated that Anxa1 is a novel endogenous defender that prevents AAD by inhibiting VSMC phenotype switching, suggesting that Anxa1 signalling may be a potential target for AAD pharmacological therapy....
CONCLUSIONS: Our findings demonstrated that Anxa1 is a novel endogenous defender that prevents AAD by inhibiting VSMC phenotype switc …
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Wang N, Ma H, Li J, Meng C, Zou J, Wang H, Liu K, Liu M, Xiao X, Zhang H, Wang K. Wang N, et al. J Mol Cell Cardiol. 2021 Jan;150:65-76. doi: 10.1016/j.yjmcc.2020.10.010. Epub 2020 Oct 22. J Mol Cell Cardiol. 2021. PMID: 33098823
Consistent with the in vitro findings, PA-challenged Hsf1(-/-) mice exhibited more serious ferroptosis, increased Slc40a1 and Fth1 mRNA expression, decreased GPX4 and TFRC expression and enhanced ER stress in the heart compared with Hsf1(+/+) mice. Altogether, HSF1 may function a …
Consistent with the in vitro findings, PA-challenged Hsf1(-/-) mice exhibited more serious ferroptosis, increased Slc40a1 and Fth1 mRNA expr …
Mfn2-mediated mitochondrial fusion alleviates doxorubicin-induced cardiotoxicity with enhancing its anticancer activity through metabolic switch.
Ding M, Shi R, Cheng S, Li M, De D, Liu C, Gu X, Li J, Zhang S, Jia M, Fan R, Pei J, Fu F. Ding M, et al. Redox Biol. 2022 Jun;52:102311. doi: 10.1016/j.redox.2022.102311. Epub 2022 Apr 5. Redox Biol. 2022. PMID: 35413642 Free PMC article.
In conclusion, targeting Mfn2-mediated mitochondrial fusion may provide a dual therapeutic advantage in Dox-based chemotherapy by simultaneously defending against Dox-induced cardiotoxicity and boosting its antitumor potency via metabolic shift....
In conclusion, targeting Mfn2-mediated mitochondrial fusion may provide a dual therapeutic advantage in Dox-based chemotherapy by simultaneo …
Hepatic prohibitin 1 and methionine adenosyltransferase alpha1 defend against primary and secondary liver cancer metastasis.
Fan W, Cao D, Yang B, Wang J, Li X, Kitka D, Li TWH, You S, Shiao S, Gangi A, Posadas E, Di Vizio D, Tomasi ML, Seki E, Mato JM, Yang H, Lu SC. Fan W, et al. J Hepatol. 2024 Mar;80(3):443-453. doi: 10.1016/j.jhep.2023.11.022. Epub 2023 Dec 10. J Hepatol. 2024. PMID: 38086446
BACKGROUND & AIMS: The liver is a common site of cancer metastasis, most commonly from colorectal cancer, and primary liver cancers that have metastasized are associated with poor outcomes. The underlying mechanisms by which the liver defends against these processes ar …
BACKGROUND & AIMS: The liver is a common site of cancer metastasis, most commonly from colorectal cancer, and primary liver cancers that …
How prosocial is moral courage?
Sasse J, Li M, Baumert A. Sasse J, et al. Curr Opin Psychol. 2022 Apr;44:146-150. doi: 10.1016/j.copsyc.2021.09.004. Epub 2021 Sep 13. Curr Opin Psychol. 2022. PMID: 34634716 Review.
Moral courage, that is, defending moral beliefs despite personal risks, is often seen as a hallmark of prosocial behavior. ...
Moral courage, that is, defending moral beliefs despite personal risks, is often seen as a hallmark of prosocial behavior. ...
WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response.
Li J, Zhang R, Wang C, Zhu J, Ren M, Jiang Y, Hou X, Du Y, Wu Q, Qi S, Li L, Chen S, Yang H, Hou F. Li J, et al. Nat Commun. 2023 Aug 10;14(1):4824. doi: 10.1038/s41467-023-40567-5. Nat Commun. 2023. PMID: 37563140 Free PMC article.
RIG-I-MAVS signaling pathway plays a crucial role in defending against pathogen infection and maintaining immune balance. ...
RIG-I-MAVS signaling pathway plays a crucial role in defending against pathogen infection and maintaining immune balance. ...
Autophagy in intracellular bacterial infection.
Hu W, Chan H, Lu L, Wong KT, Wong SH, Li MX, Xiao ZG, Cho CH, Gin T, Chan MTV, Wu WKK, Zhang L. Hu W, et al. Semin Cell Dev Biol. 2020 May;101:41-50. doi: 10.1016/j.semcdb.2019.07.014. Epub 2019 Sep 10. Semin Cell Dev Biol. 2020. PMID: 31408699 Free article. Review.
Accumulating evidences showed that a specialized form of autophagy, known as xenophagy, could serve as an innate immune response to defend against pathogens invading inside the host cells. Correspondingly, infectious pathogens have developed a variety of strategies to disa …
Accumulating evidences showed that a specialized form of autophagy, known as xenophagy, could serve as an innate immune response to defen …
822 results