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Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1-42.
Alzheimers Dement. 2020 Oct 8:10.1002/alz.12194. doi: 10.1002/alz.12194. Online ahead of print.
Alzheimers Dement. 2020.
PMID: 33090700
Free PMC article.
Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability.
Roth JR, Rush T, Thompson SJ, Aldaher AR, Dunn TB, Mesina JS, Cochran JN, Boyle NR, Dean HB, Yang Z, Pathak V, Ruiz P, Wu M, Day JJ, Bostwick JR, Suto MJ, Augelli-Szafran CE, Roberson ED.
Roth JR, et al. Among authors: dean hb.
Neurotherapeutics. 2024 Jan;21(1):e00291. doi: 10.1016/j.neurot.2023.10.001. Epub 2023 Dec 19.
Neurotherapeutics. 2024.
PMID: 38241154
Free PMC article.
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Neurodegenerative Disease-Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain.
Dean HB, Roberson ED, Song Y.
Dean HB, et al.
Front Neurol. 2019 Nov 26;10:1252. doi: 10.3389/fneur.2019.01252. eCollection 2019.
Front Neurol. 2019.
PMID: 32021611
Free PMC article.
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