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Integrating network pharmacology with microRNA microarray analysis to identify the role of miRNAs in thrombosis treated by the Dahuang Zhechong pill.
Shi R, Gao S, Huang H, Jiang K, Wang D. Shi R, et al. Comput Biol Med. 2024 May;173:108338. doi: 10.1016/j.compbiomed.2024.108338. Epub 2024 Mar 19. Comput Biol Med. 2024. PMID: 38531252 Free article.
BACKGROUND: Thrombotic diseases are the leading causes of death worldwide, urging for improvements in treatment strategies. Dahuang Zhechong pill (DHZCP) is a traditional Chinese medicine widely used for treating thrombotic diseases; however, the underlying mechanisms rema …
BACKGROUND: Thrombotic diseases are the leading causes of death worldwide, urging for improvements in treatment strategies. Dahuang Z …
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Zhang X, Wang S, Jin Y, Wang J, Wang R, Yang X, Zhang S, Yan T, Jia Y. Zhang X, et al. J Ethnopharmacol. 2023 May 23;308:116253. doi: 10.1016/j.jep.2023.116253. Epub 2023 Feb 17. J Ethnopharmacol. 2023. PMID: 36806345
ETHNOPHARMACOLOGICAL RELEVANCE: Wei-Tong-Xin (WTX) originated from the famous ancient Chinese formula "Wan Ying Yuan", recorded in the ancient Chinese medicine book "Zhong Zang Jing" by Hua Tuo. As "Jun" drugs, Dahuang and Muxiang have the effects of clearing heat and expe …
ETHNOPHARMACOLOGICAL RELEVANCE: Wei-Tong-Xin (WTX) originated from the famous ancient Chinese formula "Wan Ying Yuan", recorded in the ancie …
Advances in anti hepatic fibrotic therapy with Traditional Chinese Medicine herbal formula.
Li H. Li H. J Ethnopharmacol. 2020 Apr 6;251:112442. doi: 10.1016/j.jep.2019.112442. Epub 2019 Dec 28. J Ethnopharmacol. 2020. PMID: 31891799 Review.
RESULTS: To some extent, classical or modern TCM herbal formulae including Yinchenhao Decoction (YCHD), Xiayuxue Decoction (XYXD), Xiaochaihutang (XCHT), Yiguanjian Decoction (YGJ), Huangqi Decoction (HQD), Dahuang Zhechong Pills (DHZC), Fuzheng Huayu Formula (FZHY), Fufan …
RESULTS: To some extent, classical or modern TCM herbal formulae including Yinchenhao Decoction (YCHD), Xiayuxue Decoction (XYXD), Xiaochaih …
Network Pharmacology-Based Approach to Investigate the Molecular Targets of Rhubarb for Treating Cancer.
Jiang L, Shi Z, Yang Y. Jiang L, et al. Evid Based Complement Alternat Med. 2021 Jun 8;2021:9945633. doi: 10.1155/2021/9945633. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34211578 Free PMC article.
BACKGROUND: As a traditional Chinese medicine, rhubarb (also named Dahuang) is used to treat various diseases. OBJECTIVE: To explore the possible antitumor mechanism of rhubarb by using network pharmacology and molecular docking in this study. ...
BACKGROUND: As a traditional Chinese medicine, rhubarb (also named Dahuang) is used to treat various diseases. OBJECTIVE: To explore …
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W, Jiang Y, Ma C, Lin H, Guo Y, Liu Z. Niu W, et al. Oncol Lett. 2020 Sep;20(3):2928-2936. doi: 10.3892/ol.2020.11839. Epub 2020 Jul 9. Oncol Lett. 2020. PMID: 32782609 Free PMC article.
The present study aimed to screen the sensitivity of bladder cancer to natural compounds by using six classic anti-inflammatory and detoxifying herbs, including the ethanol extract of Paris polyphylla (PPE), Scutellaria barbata, Pulsatillae decoction, Dahuang Huanglian Xie …
The present study aimed to screen the sensitivity of bladder cancer to natural compounds by using six classic anti-inflammatory and detoxify …
Effects of Chinese herbal cataplasm Xiaozhang Tie on cirrhotic ascites.
Xing F, Tan Y, Yan GJ, Zhang JJ, Shi ZH, Tan SZ, Feng NP, Liu CH. Xing F, et al. J Ethnopharmacol. 2012 Jan 31;139(2):343-9. doi: 10.1016/j.jep.2011.10.040. Epub 2011 Nov 17. J Ethnopharmacol. 2012. PMID: 22107835 Clinical Trial.
AIM OF THE STUDY: To investigate the efficacy of Xiaozhang Tie, a traditional Chinese herbal cataplasm composed of dahuang (Rheum palmatum L.), laifuzi (Raphanus sativus L.), concocted gansui (Euphorbia kansui T.N. ...
AIM OF THE STUDY: To investigate the efficacy of Xiaozhang Tie, a traditional Chinese herbal cataplasm composed of dahuang (Rheum pal …
Mechanism of aqueous fructus aurantii immaturus extracts in neuroplexus of cathartic colons.
Wang SY, Liu YP, Fan YH, Zhang L, Cai LJ, Lv B. Wang SY, et al. World J Gastroenterol. 2015 Aug 21;21(31):9358-66. doi: 10.3748/wjg.v21.i31.9358. World J Gastroenterol. 2015. PMID: 26309361 Free PMC article.
AIM: To examine the effect of aqueous fructus aurantii immaturus (FAI) extracts on the intestinal plexus of cathartic colons. METHODS: Cathartic colons were induced in rats with dahuang, a laxative used in traditional Chinese medicine. Once the model was established (after …
AIM: To examine the effect of aqueous fructus aurantii immaturus (FAI) extracts on the intestinal plexus of cathartic colons. METHODS: Catha …
A novel UPLC-MS/MS method for simultaneous quantification of rhein, emodin, berberine and baicalin in rat plasma and its application in a pharmacokinetic study.
Huang P, Gao JW, Shi Z, Zou JL, Lu YS, Yuan YM, Yao MC. Huang P, et al. Bioanalysis. 2012 Jun;4(10):1205-13. doi: 10.4155/bio.12.81. Bioanalysis. 2012. PMID: 22651564
BACKGROUND: Dahuang Huanglian Xiexin Decoction (DHXD) is a classical formula in traditional Chinese medicines. ...
BACKGROUND: Dahuang Huanglian Xiexin Decoction (DHXD) is a classical formula in traditional Chinese medicines. ...
Optimization of high pressure machine decocting process for Dachengqi Tang using HPLC fingerprints combined with the Box-Behnken experimental design.
Xie RF, Shi ZN, Li ZC, Chen PP, Li YM, Zhou X. Xie RF, et al. J Pharm Anal. 2015 Apr;5(2):110-119. doi: 10.1016/j.jpha.2014.07.001. Epub 2014 Oct 7. J Pharm Anal. 2015. PMID: 29403922 Free PMC article.
Results of optimal process showed that the herb materials were soaked for 45 min and extracted with 9 folds volume of water in the decocting machine under the temperature of 140 C till the pressure arrived at 0.25 MPa; then hot decoction was excreted to soak Dahuang and Ma …
Results of optimal process showed that the herb materials were soaked for 45 min and extracted with 9 folds volume of water in the decocting …
Simultaneous analysis of multiple bioactive constituents in Rheum tanguticum Maxim. ex Balf. by high-performance liquid chromatography coupled to tandem mass spectrometry.
Jin W, Wang YF, Ge RL, Shi HM, Jia CQ, Tu PF. Jin W, et al. Rapid Commun Mass Spectrom. 2007;21(14):2351-60. doi: 10.1002/rcm.3086. Rapid Commun Mass Spectrom. 2007. PMID: 17593565
A simple, rapid method was developed using on-line high-performance liquid chromatography (HPLC)-diode array detection (DAD)/electrospray ionization mass spectrometry (ESI-MS) to simultaneously analyze multiple bioactive constituents in the extract of Rheum tanguticum Maxim. ex B …
A simple, rapid method was developed using on-line high-performance liquid chromatography (HPLC)-diode array detection (DAD)/electrospray io …