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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 2
1987 6
1988 3
1989 4
1990 6
1991 2
1992 8
1993 9
1995 7
1996 8
1997 9
1998 5
1999 6
2000 5
2001 1
2002 2
2003 2
2004 2
2005 2
2006 1
2010 2
2014 2
2021 1
2024 0

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96 results

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Page 1
Sustained inward current during pacemaker depolarization in mammalian sinoatrial node cells.
Mitsuiye T, Shinagawa Y, Noma A. Mitsuiye T, et al. Circ Res. 2000 Jul 21;87(2):88-91. doi: 10.1161/01.res.87.2.88. Circ Res. 2000. PMID: 10903990 Review.
Because the current showed little inactivation during depolarizing pulses, it was called the sustained inward current (I(st)). A similar current is also found in SA node cells of the guinea pig and rat and in subsidiary pacemaker atrioventricular node cells. Recently, sing …
Because the current showed little inactivation during depolarizing pulses, it was called the sustained inward current (I(st)). A simi …
Calcium modulation in epilepsy.
Kułak W, Sobaniec W, Wojtal K, Czuczwar SJ. Kułak W, et al. Pol J Pharmacol. 2004 Jan-Feb;56(1):29-41. Pol J Pharmacol. 2004. PMID: 15047975 Free article. Review.
The initiation of epileptogenic activity in the neuron is thought to be connected with the phenomenon known as "intrinsic burst firing", which is activated by an inward Ca2+ current. Ca2+ is described as the primary mediator of "excitotoxic" neuronal damage. ...In this rev …
The initiation of epileptogenic activity in the neuron is thought to be connected with the phenomenon known as "intrinsic burst firing", whi …
Low-voltage-activated inward current in murine antral smooth muscle cells is an artifact.
Lee JY, Zheng H, Sanders KM, Koh SD. Lee JY, et al. Am J Physiol Cell Physiol. 2021 Jun 1;320(6):C966-C973. doi: 10.1152/ajpcell.00031.2021. Epub 2021 Mar 31. Am J Physiol Cell Physiol. 2021. PMID: 33788632 Free PMC article.
Two types of voltage-dependent inward currents were evoked by depolarization in murine antral smooth muscle cells (SMCs) bathed in Ca(2+)-containing physiological solution: high-voltage-activated (HVA) and low-voltage-activated (LVA) inward currents. ...Replacement …
Two types of voltage-dependent inward currents were evoked by depolarization in murine antral smooth muscle cells (SMCs) bathed in Ca …
Management of systemic and pulmonary hypertension.
Levy JH. Levy JH. Tex Heart Inst J. 2005;32(4):467-71. Tex Heart Inst J. 2005. PMID: 16429888 Free PMC article. Review.
Intravenous dihydropyridine-type calcium channel blockers inhibit mechanical responses of cardiac muscle and vascular smooth muscle by blocking inward calcium currents. Nicardipine is an arterial specific vasodilator. ...
Intravenous dihydropyridine-type calcium channel blockers inhibit mechanical responses of cardiac muscle and vascular smooth muscle by block …
Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine.
Kim YC, Koh SD, Sanders KM. Kim YC, et al. J Physiol. 2002 Jun 15;541(Pt 3):797-810. doi: 10.1113/jphysiol.2002.018796. J Physiol. 2002. PMID: 12068041 Free PMC article.
Nicardipine (1 microM) blocked only half of the voltage-dependent inward current. After nicardipine, there was a shift in the potential at which peak current was obtained (-15 mV), and negative shifts in the voltage dependence of activation and inactivation o …
Nicardipine (1 microM) blocked only half of the voltage-dependent inward current. After nicardipine, there was a shift …
The sustained inward current and inward rectifier K+ current in pacemaker cells dissociated from rat sinoatrial node.
Shinagawa Y, Satoh H, Noma A. Shinagawa Y, et al. J Physiol. 2000 Mar 15;523 Pt 3(Pt 3):593-605. doi: 10.1111/j.1469-7793.2000.t01-2-00593.x. J Physiol. 2000. PMID: 10718740 Free PMC article.
A sustained inward current was activated on depolarization from -80 mV to the voltage range of slow diastolic depolarization. The current was blocked by nicardipine, enlarged by isoprenaline and was insensitive to removal of external Ca2+. ...
A sustained inward current was activated on depolarization from -80 mV to the voltage range of slow diastolic depolarization. The cur …
Inward rectifier and low-threshold calcium currents contribute to the spontaneous firing mechanism in neurons of the rat suprachiasmatic nucleus.
Akasu T, Shoji S, Hasuo H. Akasu T, et al. Pflugers Arch. 1993 Oct;425(1-2):109-16. doi: 10.1007/BF00374510. Pflugers Arch. 1993. PMID: 7903809
The inward rectification was depressed by bath application of caesium (1 mM) but not by barium (500 microM). ...Cadmium (500 microM), cobalt (1 mM) or caesium (1 mM) but not nicardipine also depressed the rebound depolarization. Under voltage-clamp conditions, hyper …
The inward rectification was depressed by bath application of caesium (1 mM) but not by barium (500 microM). ...Cadmium (500 microM), …
A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells.
Guo J, Ono K, Noma A. Guo J, et al. J Physiol. 1995 Feb 15;483 ( Pt 1)(Pt 1):1-13. doi: 10.1113/jphysiol.1995.sp020563. J Physiol. 1995. PMID: 7776225 Free PMC article.

The peak of Ist (at about -50 mV) was increased to 149 +/- 13% (n = 8, P < 0.01) by lowering the external Ca2+ concentration ([Ca2+]o) from 1.8 to 0.1 mM, in contrast to the marked depression of the L-type Ca2+ current. In 0.1 mM [Ca2+]o solution, the nicardipine-sensit

…

The peak of Ist (at about -50 mV) was increased to 149 +/- 13% (n = 8, P < 0.01) by lowering the external Ca2+ concentration ([Ca2+]o) fr

…
The sustained inward current in sino-atrial node cells of guinea-pig heart.
Guo J, Mitsuiye T, Noma A. Guo J, et al. Pflugers Arch. 1997 Feb;433(4):390-6. doi: 10.1007/s004240050293. Pflugers Arch. 1997. PMID: 9000417
Only a quite small fraction of the cell population showed spontaneous action potentials and these cells were characterized by the presence of the hyperpolarization-activated cation current If , the delayed rectifier K+ current IK and the L-type Ca2+ current ICa,L as well as by th …
Only a quite small fraction of the cell population showed spontaneous action potentials and these cells were characterized by the presence o …
Existence of a low-threshold and sustained inward current in rabbit atrio-ventricular node cells.
Guo J, Noma A. Guo J, et al. Jpn J Physiol. 1997 Aug;47(4):355-9. doi: 10.2170/jjphysiol.47.355. Jpn J Physiol. 1997. PMID: 9387078 Free article.
After blocking I(f) and IK, depolarizing pulses from -80 mV revealed a sustained inward current, which was suppressed by 1 microM nicardipine. The activation threshold of the sustained inward current was around -60 mV and the maximum amplitude was 25.4 +/- 20 …
After blocking I(f) and IK, depolarizing pulses from -80 mV revealed a sustained inward current, which was suppressed by 1 microM …
96 results