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2002 1
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2012 7
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2017 12
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105 results

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Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling.
Tian L, Zhao JL, Kang JQ, Guo SB, Zhang N, Shang L, Zhang YL, Zhang J, Jiang X, Lin Y. Tian L, et al. Front Immunol. 2021 Sep 13;12:740565. doi: 10.3389/fimmu.2021.740565. eCollection 2021. Front Immunol. 2021. PMID: 34589089 Free PMC article.
Some previous studies indicated that Astragaloside IV (AS-IV), a natural saponin extracted from the traditional Chinese medicine herb Ligusticum chuanxiong, alleviates the experimental colitis symptoms in vitro and in vivo. ...
Some previous studies indicated that Astragaloside IV (AS-IV), a natural saponin extracted from the traditional Chinese medicine herb Ligust …
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE(-/-) mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis.
Zhang Y, Li D, Jia Z, Mei J, Wang Y, Zhang Y, Zhou Q, Xu F. Zhang Y, et al. J Ethnopharmacol. 2024 Jan 30;319(Pt 1):117188. doi: 10.1016/j.jep.2023.117188. Epub 2023 Sep 15. J Ethnopharmacol. 2024. PMID: 37716492
ETHNOPHARMACOLOGICAL RELEVANCE: Gardenia Fructus (Gardenia jasminoides Ellis, Zhizi) and Chuanxiong Rhizoma (Ligusticum chuanxiong Hort., Chuanxiong) are both traditional Chinese medicines with vascular protective effects, which help detoxify and activate blo …
ETHNOPHARMACOLOGICAL RELEVANCE: Gardenia Fructus (Gardenia jasminoides Ellis, Zhizi) and Chuanxiong Rhizoma (Ligusticum chuanxiong …
Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis.
Lou T, Wu H, Feng M, Liu L, Yang X, Pan M, Wei Z, Zhang Y, Shi L, Qu B, Yang H, Cong S, Chen K, Liu J, Li Y, Jia Z, Xiao H. Lou T, et al. J Ethnopharmacol. 2024 May 10;325:117868. doi: 10.1016/j.jep.2024.117868. Epub 2024 Feb 5. J Ethnopharmacol. 2024. PMID: 38325668
ETHNOPHARMACOLOGICAL RELEVANCE: Da Chuanxiong Formula (DCX) is a traditional herbal compound composed of Gastrodia elata Bl. and Ligusticum chuanxiong Hort, which could significantly enhance blood circulation and neuroprotection, showing promise in treating Vascular …
ETHNOPHARMACOLOGICAL RELEVANCE: Da Chuanxiong Formula (DCX) is a traditional herbal compound composed of Gastrodia elata Bl. and Ligu …
Exploring the Regulatory Mechanism of Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound on HIF-VEGF Pathway and Cerebral Ischemia-Reperfusion Injury's Biological Network Based on Systematic Pharmacology.
Yang K, Zeng L, Ge A, Chen Y, Wang S, Zhu X, Ge J. Yang K, et al. Front Pharmacol. 2021 Jun 25;12:601846. doi: 10.3389/fphar.2021.601846. eCollection 2021. Front Pharmacol. 2021. PMID: 34248611 Free PMC article.
Background: Clinical research found that Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound (HCC) has definite curative effect on cerebral ischemic diseases, such as ischemic stroke and cerebral ischemia-reperfusion injury (CIR). ...
Background: Clinical research found that Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound (HCC) has definite curative effect o …
Ligusticum chuanxiong promotes the angiogenesis of preovulatory follicles (F1-F3) in late-phase laying hens.
Chen H, Chen X, Ping Z, Fang L, Jiang X, Ge M, Ma J, Yu W. Chen H, et al. Poult Sci. 2023 Mar;102(3):102430. doi: 10.1016/j.psj.2022.102430. Epub 2022 Dec 16. Poult Sci. 2023. PMID: 36621100 Free PMC article.
Ligusticum chuanxiong (CX) is a traditional Chinese medicine that is widely planted throughout the world. ...
Ligusticum chuanxiong (CX) is a traditional Chinese medicine that is widely planted throughout the world. ...
Medicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited.
Keshavarzi Z, Shakeri F, Barreto GE, Bibak B, Sathyapalan T, Sahebkar A. Keshavarzi Z, et al. Biofactors. 2019 Jul;45(4):517-535. doi: 10.1002/biof.1516. Epub 2019 Jun 17. Biofactors. 2019. PMID: 31206893 Review.
Studies with Actaea racemosa, Artemisia annua, Aframomum melegueta, Carthamus tinctorius, Cinnamomum zeylanicum, Crocus sativus, Cnidium monnieri, Curcuma longa, Gastrodia elata, Malva sylvestris, Da Chuanxiong Formula, Erigeron breviscapus, Panax ginseng, Salvia tomentosa …
Studies with Actaea racemosa, Artemisia annua, Aframomum melegueta, Carthamus tinctorius, Cinnamomum zeylanicum, Crocus sativus, Cnidium mon …
Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy.
Li C, Ma J, Mali N, Zhang L, Wei T, Shi L, Liu F, WenXing F, Yang J. Li C, et al. Mol Med. 2022 Nov 18;28(1):136. doi: 10.1186/s10020-022-00567-5. Mol Med. 2022. PMID: 36401196 Free PMC article.
METHODS: To get the components and pharmacodynamic targets of Chuanxiong, we identified by searching TCMID, TCMSP, ETCM and HERB databases. ...CONCLUSION: The improvement of DN by Chuanxiong is related to the change of pyroptosis....
METHODS: To get the components and pharmacodynamic targets of Chuanxiong, we identified by searching TCMID, TCMSP, ETCM and HERB data …
Research on the potential mechanism of Chuanxiong Rhizoma on treating Diabetic Nephropathy based on network pharmacology.
Hu S, Chen S, Li Z, Wang Y, Wang Y. Hu S, et al. Int J Med Sci. 2020 Aug 21;17(15):2240-2247. doi: 10.7150/ijms.47555. eCollection 2020. Int J Med Sci. 2020. PMID: 32922187 Free PMC article.
Background: Chuanxiong Rhizoma is one of the traditional Chinese medicines which have been used for years in the treatment of diabetic nephropathy (DN). However, the mechanism of Chuanxiong Rhizoma in DN has not yet been fully understood. Methods: We performed netwo …
Background: Chuanxiong Rhizoma is one of the traditional Chinese medicines which have been used for years in the treatment of diabeti …
Effects of Ligusticum chuanxiong and Gastrodia elata on blood-brain barrier permeability in migraine rats.
Wang Q, Shen L, Ma S, Chen M, Lin X, Hong Y, Liang S, Feng Y. Wang Q, et al. Pharmazie. 2015 Jun;70(6):421-6. Pharmazie. 2015. PMID: 26189306
The two herbs Ligusticum chuanxiong (LC) Hort. (Umbelliferae) and Gastrodia elata (GE) Blume (Orchidaceae), are widely used in the clinic for the treatment of migraine. ...EBD levels in rat brain were significantly lower at 30-60 min and 120-150 min in LC-GE …
The two herbs Ligusticum chuanxiong (LC) Hort. (Umbelliferae) and Gastrodia elata (GE) Blume (Orchidaceae), are widely used in …
Naotaifang III Protects Against Cerebral Ischemia Injury Through LPS/TLR4 Signaling Pathway in the Microbiota-Gut-Brain Axis.
Nie H, Ge J, Yang K, Peng Z, Wu H, Yang T, Mei Z. Nie H, et al. Drug Des Devel Ther. 2023 Dec 1;17:3571-3588. doi: 10.2147/DDDT.S421658. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 38058793 Free PMC article.
Previous studies have shown that Astragali Radix, Puerariae Lobatae Radix, Chuanxiong Rhizoma, and Rhei Radix Et Rhizoma in Naotaifang III were able to regulate the imbalance of intestinal microbiota during cerebral ischemia injury. ...
Previous studies have shown that Astragali Radix, Puerariae Lobatae Radix, Chuanxiong Rhizoma, and Rhei Radix Et Rhizoma in Naotaifan …
105 results