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Year Number of Results
1999 1
2002 1
2006 1
2007 2
2008 1
2010 3
2011 3
2012 1
2013 2
2014 6
2015 9
2016 9
2017 6
2018 7
2019 8
2020 8
2021 5
2022 6
2023 5
2024 2

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78 results

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Page 1
Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion.
Chakravarty D, Johnson A, Sklar J, Lindeman NI, Moore K, Ganesan S, Lovly CM, Perlmutter J, Gray SW, Hwang J, Lieu C, André F, Azad N, Borad M, Tafe L, Messersmith H, Robson M, Meric-Bernstam F. Chakravarty D, et al. J Clin Oncol. 2022 Apr 10;40(11):1231-1258. doi: 10.1200/JCO.21.02767. Epub 2022 Feb 17. J Clin Oncol. 2022. PMID: 35175857
CLINICAL CONTEXT: An increasing number of therapies are approved to treat cancers harboring specific genomic biomarkers. However, there is a lack of clarity as to when tumor genomic sequencing should be ordered, what type of assays should be performed, and how to interpret …
CLINICAL CONTEXT: An increasing number of therapies are approved to treat cancers harboring specific genomic biomarkers. However, the …
SARS/avian coronaviruses.
Monceyron Jonassen C. Monceyron Jonassen C. Dev Biol (Basel). 2006;126:161-9; discussion 326-7. Dev Biol (Basel). 2006. PMID: 17058491
The three other coronavirus probes, that hybridised with the SARS agent, were located in the replicase gene, and it could be concluded that the SARS agent was a novel coronavirus, harbouring s2m. The presence of this motif in different virus families is probably the result …
The three other coronavirus probes, that hybridised with the SARS agent, were located in the replicase gene, and it could be concluded that …
Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.
Robertson DJ, Dominitz JA, Beed A, Boardman KD, Del Curto BJ, Guarino PD, Imperiale TF, LaCasse A, Larson MF, Gupta S, Lieberman D, Planeta B, Shaukat A, Sultan S, Menees SB, Saini SD, Schoenfeld P, Goebel S, von Rosenvinge EC, Baffy G, Halasz I, Pedrosa MC, Kahng LS, Cassim R, Greer KB, Kinnard MF, Bhatt DB, Dunbar KB, Harford WV Jr, Mengshol JA, Olson JE, Patel SG, Antaki F, Fisher DA, Sullivan BA, Lenza C, Prajapati DN, Wong H, Beyth R, Lieb JG 2nd, Manlolo J, Ona FV, Cole RA, Khalaf N, Kahi CJ, Kohli DR, Rai T, Sharma P, Anastasiou J, Hagedorn C, Fernando RS, Jackson CS, Jamal MM, Lee RH, Merchant F, May FP, Pisegna JR, Omer E, Parajuli D, Said A, Nguyen TD, Tombazzi CR, Feldman PA, Jacob L, Koppelman RN, Lehenbauer KP, Desai DS, Madhoun MF, Tierney WM, Ho MQ, Hockman HJ, Lopez C, Carter Paulson E, Tobi M, Pinillos HL, Young M, Ho NC, Mascarenhas R, Promrat K, Mutha PR, Pandak WM Jr, Shah T, Schubert M, Pancotto FS, Gawron AJ, Underwood AE, Ho SB, Magno-Pagatzaurtundua P, Toro DH, Beymer CH, Kaz AM, Elwing J, Gill JA, Goldsmith SF, Yao MD, Protiva P, Pohl H, Kyriakides T; CONFIRM Study Group. Robertson DJ, et al. JAMA Netw Open. 2023 Jul 3;6(7):e2321730. doi: 10.1001/jamanetworkopen.2023.21730. JAMA Netw Open. 2023. PMID: 37432690 Free PMC article. Clinical Trial.
Mesonephric-like adenocarcinoma of the female genital tract: possible role of KRAS-targeted treatment-detailed molecular analysis of a case series and review of the literature for targetable somatic KRAS-mutations.
Brambs CE, Horn LC, Hiller R, Krücken I, Braun C, Christmann C, Monecke A, Höhn AK. Brambs CE, et al. J Cancer Res Clin Oncol. 2023 Nov;149(17):15727-15736. doi: 10.1007/s00432-023-05306-9. Epub 2023 Sep 5. J Cancer Res Clin Oncol. 2023. PMID: 37668797 Free PMC article. Review.
These cases as well as the data of previously published cases with detailed information regarding KRAS-mutational events were reviewed for a potential targeted approach and its prognostic impact. RESULTS: Both the uterine and ovarian MLA harbor a somatic KRAS-mutation in a …
These cases as well as the data of previously published cases with detailed information regarding KRAS-mutational events were reviewed for a …
NTRK fusion events and targeted treatment of advanced radioiodine refractory thyroid cancer.
Koehler VF, Achterfeld J, Sandner N, Koch C, Wiegmann JP, Ivanyi P, Käsmann L, Pusch R, Wolf D, Chirica M, Knösel T, Demes MC, Kumbrink J, Vogl TJ, Meyer G, Spitzweg C, Bojunga J, Kroiss M. Koehler VF, et al. J Cancer Res Clin Oncol. 2023 Nov;149(15):14035-14043. doi: 10.1007/s00432-023-05134-x. Epub 2023 Aug 7. J Cancer Res Clin Oncol. 2023. PMID: 37548775 Free PMC article.
Progression-free survival (PFS) and overall survival (OS) probabilities were estimated using the Kaplan-Meier method in six patients with NTRK fusion-positive TC who underwent TRK inhibitor therapy. RESULTS: 8/184 (4%) patients harbored NTRK gene fusions. Six patients with …
Progression-free survival (PFS) and overall survival (OS) probabilities were estimated using the Kaplan-Meier method in six patients with NT …
Subcutaneous white adipose tissue: The deepest layer of the cutaneous immune barrier.
Brüggen MC, Stingl G. Brüggen MC, et al. J Dtsch Dermatol Ges. 2020 Nov;18(11):1225-1227. doi: 10.1111/ddg.14335. Epub 2020 Nov 16. J Dtsch Dermatol Ges. 2020. PMID: 33197138 Review.
An immunophenotypic analysis of liposuction-derived SWAT demonstrated that healthy subcutaneous fat tissue, although showing no overt signs of inflammation, harbors an indigenous system of immunocytes. As opposed to epidermis and dermis, they belong mainly to the mononucle …
An immunophenotypic analysis of liposuction-derived SWAT demonstrated that healthy subcutaneous fat tissue, although showing no overt signs …
Translational Genomics: Practical Applications of the Genomic Revolution in Breast Cancer.
Yates LR, Desmedt C. Yates LR, et al. Clin Cancer Res. 2017 Jun 1;23(11):2630-2639. doi: 10.1158/1078-0432.CCR-16-2548. Clin Cancer Res. 2017. PMID: 28572257
Most breast cancers contain subclonal populations, many of which harbor driver alterations, and subclonal structure is typically remodeled over time, across metastasis and as a consequence of treatment interventions. ...
Most breast cancers contain subclonal populations, many of which harbor driver alterations, and subclonal structure is typically remo …
[Large cell carcinoma, lymphoepithelioma-like carcinoma, NUT carcinoma].
Copin MC. Copin MC. Ann Pathol. 2016 Jan;36(1):24-33. doi: 10.1016/j.annpat.2015.11.006. Epub 2015 Dec 28. Ann Pathol. 2016. PMID: 26739900 Review. French.
These carcinomas have an adenocarcinoma molecular profile because they harbor a significant number of KRAS and BRAF mutations, a profile that is more similar to adenocarcinoma than squamous cell carcinoma. ...
These carcinomas have an adenocarcinoma molecular profile because they harbor a significant number of KRAS and BRAF mutations, a prof …
Parkin-linked Parkinson's disease: From clinical insights to pathogenic mechanisms and novel therapeutic approaches.
Wasner K, Grünewald A, Klein C. Wasner K, et al. Neurosci Res. 2020 Oct;159:34-39. doi: 10.1016/j.neures.2020.09.001. Epub 2020 Sep 17. Neurosci Res. 2020. PMID: 32949666 Review.
In the recent years, however, additional functions of the protein are beginning to come to light, which in turn may influence the way patients harboring Parkin mutations are treated. In the present article, we discuss the clinical and genetic aspects of Parkin-linked PD. . …
In the recent years, however, additional functions of the protein are beginning to come to light, which in turn may influence the way patien …
78 results