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Ultrasmall iron-gallic acid coordination polymer nanodots with antioxidative neuroprotection for PET/MR imaging-guided ischemia stroke therapy.
Du Y, Huo Y, Yang Q, Han Z, Hou L, Cui B, Fan K, Qiu Y, Chen Z, Huang W, Lu J, Cheng L, Cai W, Kang L. Du Y, et al. Among authors: cheng l. Exploration (Beijing). 2023 Jan 17;3(1):20220041. doi: 10.1002/EXP.20220041. eCollection 2023 Feb. Exploration (Beijing). 2023. PMID: 37323619 Free PMC article.
Furthermore, immunohistochemistry staining indicated that Fe-GA CPNs inhibited apoptosis through protein kinase B (Akt) restoration, whereas western blot and immunofluorescence indicated the activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 …
Furthermore, immunohistochemistry staining indicated that Fe-GA CPNs inhibited apoptosis through protein kinase B (Akt) restoration, whereas …
The efficacy of a multimodal analgesia protocol in preventing heterotopic ossification after acetabular fractures surgery.
Cheng L, Long HT, Sun BH, Zhao SS, Zhu Y. Cheng L, et al. Int J Clin Pharm. 2017 Aug;39(4):826-830. doi: 10.1007/s11096-017-0476-9. Epub 2017 May 12. Int J Clin Pharm. 2017. PMID: 28500436
Background Heterotopic ossification (HO) after joint surgery is always a disturbing problem for patients and surgeons. ...Main outcome measure The differences in HO incidence and severity between the two groups. Results 49 patients (30.0%) developed HO in the …
Background Heterotopic ossification (HO) after joint surgery is always a disturbing problem for patients and surgeons. ...Main outcom …
MiR-19b-3p regulates osteogenic differentiation of PDGFRα+ muscle cells by specifically targeting PTEN.
Zhu Y, Long HT, Zeng L, Tang YF, Zhao RB, Lin ZY, Zhao SS, Cheng L. Zhu Y, et al. Among authors: cheng l. Cell Biol Int. 2019 May;43(5):565-573. doi: 10.1002/cbin.11133. Epub 2019 Apr 25. Cell Biol Int. 2019. PMID: 30958604
Heterotopic ossification (HO) is a common disturbing complication of intra-articular fractures. ...In conclusion, our results suggested that miR-19b-3p may be a promising target in inhibiting PDGFRalpha(+) muscle cell osteogenic differentiation and treatment of HO.. …
Heterotopic ossification (HO) is a common disturbing complication of intra-articular fractures. ...In conclusion, our results suggest …
α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway.
Deng C, Sun Z, Tong G, Yi W, Ma L, Zhao B, Cheng L, Zhang J, Cao F, Yi D. Deng C, et al. Among authors: cheng l. PLoS One. 2013;8(3):e58371. doi: 10.1371/journal.pone.0058371. Epub 2013 Mar 7. PLoS One. 2013. PMID: 23505496 Free PMC article.
Western blot analysis showed that LA pretreatment up-regulated Akt phosphorylation and Nrf2 nuclear translocation while producing no impact on p38MAPK activation or nitric oxide (NO) production. LA pretreatment also increased expression of HO-1, a major target of Nrf2. LA …
Western blot analysis showed that LA pretreatment up-regulated Akt phosphorylation and Nrf2 nuclear translocation while producing no impact …