DNA damage-free iPS cells exhibit potential to yield competent cardiomyocytes.
Miller JM, Mardhekar NM, Pretorius D, Krishnamurthy P, Rajasekaran NS, Zhang J, Kannappan R.
Miller JM, et al.
Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H801-H815. doi: 10.1152/ajpheart.00658.2019. Epub 2020 Feb 14.
Am J Physiol Heart Circ Physiol. 2020.
PMID: 32057252
Free PMC article.
Additionally, DdF-CMs were able to retain the improved molecular, cellular, and physiological functions after differentiation from iPSCs, and, interestingly, cardiac development network was prominent compared with Ctrl-CMs. Enhanced expression of various ion channel transc …
Additionally, DdF-CMs were able to retain the improved molecular, cellular, and physiological functions after differentiation from iPSCs, an …