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1991 1
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16 results

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Page 1
Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants.
Egbuna O, Zimmerman B, Manos G, Fortier A, Chirieac MC, Dakin LA, Friedman DJ, Bramham K, Campbell K, Knebelmann B, Barisoni L, Falk RJ, Gipson DS, Lipkowitz MS, Ojo A, Bunnage ME, Pollak MR, Altshuler D, Chertow GM; VX19-147-101 Study Group. Egbuna O, et al. N Engl J Med. 2023 Mar 16;388(11):969-979. doi: 10.1056/NEJMoa2202396. N Engl J Med. 2023. PMID: 36920755 Clinical Trial.
RESULTS: In preclinical studies, inaxaplin selectively inhibited APOL1 channel function in vitro and reduced proteinuria in the mouse model. ...Adverse events were mild or moderate in severity; none led to study discontinuation. CONCLUSIONS: Targeted inhibition of APOL1 …
RESULTS: In preclinical studies, inaxaplin selectively inhibited APOL1 channel function in vitro and reduced proteinuria in the mouse …
Targeting Calcium Release-activated Calcium Channel Is Not Sufficient to Prevent Rejection in Nonhuman Primate Kidney Transplantation.
Kwun J, Ezekian B, Manook M, Park J, Yoon J, Freischlag K, Song M, Farris AB, Sloan-Lancaster J, Fortier C, Rao PE, Knechtle SJ. Kwun J, et al. Transplantation. 2020 May;104(5):970-980. doi: 10.1097/TP.0000000000003078. Transplantation. 2020. PMID: 32317615 Free PMC article.
This study, using a rhesus monkey renal transplantation model, sought to determine the applicability of a new immunomodulatory drug inhibiting the store-operated calcium release-activated calcium channel of lymphocytes to control transplant rejection without nephrotoxicity …
This study, using a rhesus monkey renal transplantation model, sought to determine the applicability of a new immunomodulatory drug inhibiti …
Capacity of UWB wireless channel for neural recording systems.
El Khaled M, Bahrami H, Fortier P, Gosselin B, Rusch LA. El Khaled M, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:3965-8. doi: 10.1109/EMBC.2014.6944492. Annu Int Conf IEEE Eng Med Biol Soc. 2014. PMID: 25570860
In this work, we are interested in the evaluation of the capacity of the ultra wide-band (UWB) channel that we could exploit using a realistic model of the biological channel. The channel characteristics are examined under two scenarios that are related to TX …
In this work, we are interested in the evaluation of the capacity of the ultra wide-band (UWB) channel that we could exploit using a …
Subjective feeling of control during fNIRS-based neurofeedback targeting the DL-PFC is related to neural activation determined with short-channel correction.
Godet A, Serrand Y, Fortier A, Léger B, Bannier E, Val-Laillet D, Coquery N. Godet A, et al. PLoS One. 2023 Aug 16;18(8):e0290005. doi: 10.1371/journal.pone.0290005. eCollection 2023. PLoS One. 2023. PMID: 37585456 Free PMC article. Clinical Trial.
Here, we examined the feasibility of a NF training targeting the DL-PFC and its specificity by assessing the impact of physiological confounds on NF success via short-channel offline correction under different signal filtering conditions. ...This number dropped to 13 (43%) …
Here, we examined the feasibility of a NF training targeting the DL-PFC and its specificity by assessing the impact of physiological confoun …
Novel Wearable HD-EMG Sensor With Shift-Robust Gesture Recognition Using Deep Learning.
Chamberland F, Buteau E, Tam S, Campbell E, Mortazavi A, Scheme E, Fortier P, Boukadoum M, Campeau-Lecours A, Gosselin B. Chamberland F, et al. IEEE Trans Biomed Circuits Syst. 2023 Oct;17(5):968-984. doi: 10.1109/TBCAS.2023.3314053. Epub 2023 Nov 21. IEEE Trans Biomed Circuits Syst. 2023. PMID: 37695958
The solution includes a novel, full-circumference, flexible, 64-channel high-density electromyography (HD-EMG) sensor called EMaGer. ...
The solution includes a novel, full-circumference, flexible, 64-channel high-density electromyography (HD-EMG) sensor called EMaGer. …
EMaGer: A Wearable Full-Circumference HD-EMG Sensor and Data Augmentation Method for Robust Hand Gesture Recognition.
Chamberland F, Buteau E, Tam S, Fortier P, Boukadoum M, Campeau-Lecours A, Gosselin B. Chamberland F, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-5. doi: 10.1109/EMBC40787.2023.10340612. Annu Int Conf IEEE Eng Med Biol Soc. 2023. PMID: 38083603
This work presents EMaGer, a new 360 64-channel high-density electromyography (HD-EMG) bracelet combined with an original data augmentation method for improved robustness in gesture recognition. ...
This work presents EMaGer, a new 360 64-channel high-density electromyography (HD-EMG) bracelet combined with an original data augmen …
A Wireless Optogenetic Headstage with Multichannel Electrophysiological Recording Capability.
Gagnon-Turcotte G, Kisomi AA, Ameli R, Camaro CO, LeChasseur Y, Néron JL, Bareil PB, Fortier P, Bories C, de Koninck Y, Gosselin B. Gagnon-Turcotte G, et al. Sensors (Basel). 2015 Sep 9;15(9):22776-97. doi: 10.3390/s150922776. Sensors (Basel). 2015. PMID: 26371006 Free PMC article.
The headstage is suitable for conducting experiments with small transgenic rodents, and features two implantable fiber-coupled light-emitting diode (LED) and two electrophysiological recording channels. This system is powered by a small lithium-ion battery and is entirely …
The headstage is suitable for conducting experiments with small transgenic rodents, and features two implantable fiber-coupled light-emittin …
The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention.
Dummer TJB, Awadalla P, Boileau C, Craig C, Fortier I, Goel V, Hicks JMT, Jacquemont S, Knoppers BM, Le N, McDonald T, McLaughlin J, Mes-Masson AM, Nuyt AM, Palmer LJ, Parker L, Purdue M, Robson PJ, Spinelli JJ, Thompson D, Vena J, Zawati M; with the CPTP Regional Cohort Consortium. Dummer TJB, et al. CMAJ. 2018 Jun 11;190(23):E710-E717. doi: 10.1503/cmaj.170292. CMAJ. 2018. PMID: 29891475 Free PMC article.
Integrated microfluidic devices with enhanced separation performance: application to phosphoproteome analyses of differentiated cell model systems.
Ghitun M, Bonneil E, Fortier MH, Yin H, Killeen K, Thibault P. Ghitun M, et al. J Sep Sci. 2006 Jul;29(11):1539-49. doi: 10.1002/jssc.200500407. J Sep Sci. 2006. PMID: 16922269
RP adsorbant media with different alkyl chains and particle size packed in both trapping and separation channels were investigated to improve the chromatographic performance of this system. A two-fold improvement in chromatographic peak capacity was achieved using microflu …
RP adsorbant media with different alkyl chains and particle size packed in both trapping and separation channels were investigated to …
Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations.
Fortier LA, Nixon AJ. Fortier LA, et al. J Rheumatol. 1997 Mar;24(3):524-30. J Rheumatol. 1997. PMID: 9058660
SP nerve fibers were evident in the articular capsule and periosteum, and their appearance and frequency were similar to nonarthritic MCP articulations. Abnormal cartilage structures such as erosion channels and osteophytes on the dorsal proximal phalangeal perimeter conta …
SP nerve fibers were evident in the articular capsule and periosteum, and their appearance and frequency were similar to nonarthritic MCP ar …
16 results